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1. ADL

activities of daily living

2. ANC

absolute neutrophil count, the absolute number of bacterial infection fighting blood cells low means notably higher risk for infection

3. Atalectasis

incomplete expansion of a portion of the lung or the whole lung

4. BAC

bronchioloalveolar carcinoma, a unique and uncommon subtype of lung cancer

5. CR

complete response (after treatment), leading to no evidence of disease (NED)

6. CT

computerized tomography, "cat scan", a detailed look at the body at varying levels internally, "slice by slice"

7. CT/PET

a combined scan that does a simultaneous CT, which measures the shape and size of body structures, with PET, which measures metabolic activity. The images can then

8. CTC

circulating tumor cells, in blood

9. CTCs

circulating tumor cells

10. CXR

chest x-ray

11. DCR

disease control rate, the combination of response rate and proportion of patients achieving stable disease

12. DNI

"do not intubate", an order to not place an endotracheal ("breathing") tube down the trachea (windpipe) in order to be placed on a mechanical ventilation machine

13. DNR

"do not resuscitate", an order to not perform chest compressions, defibrillation, etc., in the event that a person is unresponsive and has no pulse, etc.

14. Dx

diagnosis

15. EGFR

epidermal growth factor receptor, a key target that modulates growth and division of cancer cells

16. FISH

fluorescence in situ hybridization, a method for detecting the number of copies of a gene in tumor cells, "positive" being higher than expected for a normal cell

17. Gy

Gray, the units of radiation dosing

18. HCT

the percentage of blood that is comprised of red blood cells, normally approximately 38-45%, but commonly below that in patients receiving cancer treatment

19. Hematocrit

the percentage of blood that is comprised of red blood cells, normally approximately 38-45%, but commonly below that in patients receiving cancer treatment

20. IHC

immunohistochemistry, a method for detecting levels of specific proteins on tumor cells

21. INR

international normalized ratio, a measurement of the degree of blood thinning, compared to an international standard, in which an INR of 2 corresponds to blood requiring twice as long as normal blood to develop a clot

22. IV

intravenous

23. LAN

lymphadenopathy, abnormally enlarged lymph nodesmedian the number within a population for which half of the values are above and half are below it; this reflects the general trend of how a population does but discounts the "pull" of the extremes on either side

24. MRI

magnetic resonance imaging, a type of scan particularly good at evaluating brain, muscle, bone, nerves

25. N/V

nausea and vomiting

26. NED

no evidence of disease, a nice report to get

27. NSCLC

non-small cell lung cancer, main subtypes including adenocarcinoma, squamous cell carcinoma, and large cell carcinoma

28. ORR

objective response rate

29. OS

overall survival

30. p value

the probability that an observed occurrence would occur by chance alone; convention is that something is considered "statistically significant" if the "p-value" is less than 0.05, translating to a less than 5% chance of the event occurring by chance.

31. PCR

polymerase chain reaction, a sensitive method for detecting gene mutations in cancer cells

32. PD

progressive disease

33. PEG

percutaneous endoscopic gastrostromy tube, or G-tube tube placed endoscopically that is anchored in the stomach and passes out through the abdominal wall, through which "tube feedings" of nutrition and fluids, as well as medicines, can be administered

34. PET

positron-emission tomography, a type of scan that measures metabolic activity, which tends to highlight areas of cancer

35. PFS

progression-free survival, the time before a patient demonstrates progression

36. platelets

blood cells that contribute to the clotting process, normally in the 150,000 450,000 range, although commonly below that in patients receiving cancer treatment

37. PLT

platelets

38. PO

oral, by mouth

39. PR

partial response (generally defined as ~50% tumor shrinkage, or greater)

40. PRN

as needed

41. PS

performance status, commonly measured on a scale from 0 (asymptomatic, unrestricted) to 5 (dead)

42. Pt

patient

43. Px

prognosis

44. QOL

quality of life

45. RBC

red blood cells, the oxygen carrying blood cells (anemia means low RBC levels)

46. RR

response rate

47. RT

Radiation therapy

48. Rx

treatment

49. SCLC

small cell lung cancer staged as LD and ED for limited disease and extensive disease, respectively (often written as SCLC-ED, for instance)

50. SD

stable disease

51. SUV

standard uptake value, the unit of measuring metabolic activity on a PET scan

52. Tx

treatment

53. VEGF

vascular endothelial growth factor, the most important modulator of new blood vessel formation, and the target for "anti-angiogenic" agents

54. WBC

white blood cells, infection fighting blood cells, of which there are a few types

55. XRT

external beam radiation therapy (basically, standard radiation)