GRACE :: Treatments & Symptom Management

Dr Zucker

Easing the Strain of Cancer-Related Fatigue and “Chemo-Brain”

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In recent years, more people are cured or living with cancer as a chronic illness because cancer treatments have improved. As a result, treatment after effects and the challenges they present are becoming increasingly apparent. Two common after effects are cancer-related fatigue (CRF) and cognitive impairment, also known as “chemo-brain.” The National Comprehensive Cancer Network defines CRF as “a persistent sense of tiredness related to cancer or cancer treatment that interferes with usual functioning.” It is different from the every-day tiredness that can affect anyone, and is not readily relieved by rest or sleep.

“Chemo-brain” may occur after chemotherapy and can include difficulties with memory, concentration, language, attention, reaction time, organizational skills and other mental functions. It’s becoming increasingly recognized as a very real and significant medical problem. Many patients experience excessive fatigue or cognitive difficulties following their cancer treatments, which can be very distressing. Fatigue is the most common side effect of cancer and cancer treatment. And we know that cancer-related fatigue can compound the effect of chemo-brain and, likewise, that chemo-brain can increase cancer-related fatigue.

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