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	<title>GRACE :: Treatments &#38; Symptom Management</title>
	<atom:link href="http://cancergrace.org/cancer-treatments/feed/" rel="self" type="application/rss+xml" />
	<link>http://cancergrace.org/cancer-treatments</link>
	<description>Expert-mediated discussion of cancer management</description>
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	<itunes:summary>Expert-mediated discussion of cancer management</itunes:summary>
	<itunes:author>GRACE :: Treatments &amp; Symptom Management</itunes:author>
	<itunes:explicit>no</itunes:explicit>
	<itunes:image href="http://cancergrace.org/cancer-treatments/wp-content/plugins/powerpress/itunes_default.jpg" />
	<itunes:subtitle>Expert-mediated discussion of cancer management</itunes:subtitle>
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		<title>GRACE :: Treatments &amp; Symptom Management</title>
		<url>http://cancergrace.org/cancer-treatments/wp-content/plugins/powerpress/rss_default.jpg</url>
		<link>http://cancergrace.org/cancer-treatments</link>
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		<item>
		<title>Can You Get &#8220;Chemo-Brain&#8221; Without Getting Chemo?</title>
		<link>http://cancergrace.org/cancer-treatments/2012/04/30/can-you-get-chemo-brain-without-getting-chemo/</link>
		<comments>http://cancergrace.org/cancer-treatments/2012/04/30/can-you-get-chemo-brain-without-getting-chemo/#comments</comments>
		<pubDate>Mon, 30 Apr 2012 16:26:59 +0000</pubDate>
		<dc:creator>Dr Cianfrocca</dc:creator>
				<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Chemo-Brain]]></category>
		<category><![CDATA[chemobrain]]></category>
		<category><![CDATA[cognitive dysfunction]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=2145</guid>
		<description><![CDATA[Cognitive dysfunction among cancer survivors, particularly breast cancer survivors has received increased attention in recent years and is frequently referred to as “chemobrain” as patients view it as a side effect of their chemotherapy. This term became popular after women with breast cancer began noticing mental “fogginess”, concentration issues and memory difficulties beginning around the [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2012/04/30/can-you-get-chemo-brain-without-getting-chemo/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>The Biology of Aspirin</title>
		<link>http://cancergrace.org/cancer-treatments/2012/04/18/the-biology-of-aspirin/</link>
		<comments>http://cancergrace.org/cancer-treatments/2012/04/18/the-biology-of-aspirin/#comments</comments>
		<pubDate>Wed, 18 Apr 2012 18:01:16 +0000</pubDate>
		<dc:creator>Dr Quesnelle</dc:creator>
				<category><![CDATA[Cancer 101]]></category>
		<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Novel Targeted Therapies]]></category>
		<category><![CDATA[aspirin]]></category>
		<category><![CDATA[cancer biology]]></category>
		<category><![CDATA[COX-2]]></category>
		<category><![CDATA[cyclooxygenase]]></category>
		<category><![CDATA[NOSH aspirin]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=2056</guid>
		<description><![CDATA[There is newfound excitement in the world of cancer over the role of aspirin, thanks to a recent study in the journal Lancet on the chemopreventive effects of aspirin.  This article was published on the heels of a media frenzy surrounding the invention of a new “super aspirin” called NOSH-aspirin.   Because of all the renewed interest [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2012/04/18/the-biology-of-aspirin/feed/</wfw:commentRss>
		<slash:comments>9</slash:comments>
		</item>
		<item>
		<title>Hematopoiesis (Creating New Blood Cells) and Growth Factors</title>
		<link>http://cancergrace.org/cancer-treatments/2012/04/13/hematopoiesis-and-growth-factors/</link>
		<comments>http://cancergrace.org/cancer-treatments/2012/04/13/hematopoiesis-and-growth-factors/#comments</comments>
		<pubDate>Fri, 13 Apr 2012 18:29:22 +0000</pubDate>
		<dc:creator>Dr Walko</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[anemia]]></category>
		<category><![CDATA[blood cells]]></category>
		<category><![CDATA[Darbepoeitin]]></category>
		<category><![CDATA[eltrombopag]]></category>
		<category><![CDATA[EPO]]></category>
		<category><![CDATA[Epogen]]></category>
		<category><![CDATA[erythrocytes]]></category>
		<category><![CDATA[erythropoietin]]></category>
		<category><![CDATA[G-CSF]]></category>
		<category><![CDATA[growth factors]]></category>
		<category><![CDATA[hematopoiesis]]></category>
		<category><![CDATA[Neulasta]]></category>
		<category><![CDATA[neutrophil]]></category>
		<category><![CDATA[Nplate]]></category>
		<category><![CDATA[Pegfilgrastim]]></category>
		<category><![CDATA[Procrit]]></category>
		<category><![CDATA[Promacta]]></category>
		<category><![CDATA[RBCs]]></category>
		<category><![CDATA[red blood cells]]></category>
		<category><![CDATA[romiplostim]]></category>
		<category><![CDATA[thrombopoietin]]></category>
		<category><![CDATA[WBCs]]></category>
		<category><![CDATA[white blood cells]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=2023</guid>
		<description><![CDATA[There are numerous types of cells that make up the bone marrow, each with their own specific function.  I’m going to focus on the three most commonly affected by chemotherapy: neutrophils (white blood cells), erythrocytes (red blood cells, measured by hemoglobin or hematocrit) and platelets (blood clotting cells).  These cells are born primarily in the [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2012/04/13/hematopoiesis-and-growth-factors/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Next Webinar: Let&#8217;s Talk About Pain, Nausea, and Vomiting with Dr. Harman on a Friday Afternoon!</title>
		<link>http://cancergrace.org/cancer-treatments/2012/04/04/harmanwebinar/</link>
		<comments>http://cancergrace.org/cancer-treatments/2012/04/04/harmanwebinar/#comments</comments>
		<pubDate>Thu, 05 Apr 2012 00:09:02 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[General]]></category>
		<category><![CDATA[Supportive care]]></category>
		<category><![CDATA[cancer pain]]></category>
		<category><![CDATA[Cancer-Related Fatigue]]></category>
		<category><![CDATA[Depression]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[nausea]]></category>
		<category><![CDATA[opioid]]></category>
		<category><![CDATA[Palliative care]]></category>
		<category><![CDATA[vomiting]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1978</guid>
		<description><![CDATA[OK, it&#8217;s not as glamorous as a new molecular marker or treatment, but topics like pain control, nausea and vomiting, depression, and fatigue are absolutely important in the lives of cancer patients and caregivers.  Dr. Stephanie Harman, faculty member at Stanford University (and GRACE), is an expert in helping people live better and more comfortably, [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2012/04/04/harmanwebinar/feed/</wfw:commentRss>
		<slash:comments>1</slash:comments>
		</item>
		<item>
		<title>Drug Development Update: MEK Inhibitors</title>
		<link>http://cancergrace.org/cancer-treatments/2012/03/07/drug-development-update-mek-inhibitors/</link>
		<comments>http://cancergrace.org/cancer-treatments/2012/03/07/drug-development-update-mek-inhibitors/#comments</comments>
		<pubDate>Wed, 07 Mar 2012 17:38:58 +0000</pubDate>
		<dc:creator>Dr Quesnelle</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Novel Targeted Therapies]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[downstream target]]></category>
		<category><![CDATA[MAPK/ERK kinase]]></category>
		<category><![CDATA[MEK]]></category>
		<category><![CDATA[Raf]]></category>
		<category><![CDATA[Ras]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1861</guid>
		<description><![CDATA[Growth factor receptors are well-known targets for cancer drugs like Tarceva (erlotinib), Tykerb (lapatinib), and Avastin (bevacizumab), among others.  These receptors activate cell growth by initiating a chain of events that results in progression of the cell cycle which leads to cell division.  You have probably heard about the growth factor receptors EGFR, HER2, and [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2012/03/07/drug-development-update-mek-inhibitors/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>Cancer Drug Shortages: Why, and What Can Be Done?</title>
		<link>http://cancergrace.org/cancer-treatments/2012/02/28/cancer-drug-shortages/</link>
		<comments>http://cancergrace.org/cancer-treatments/2012/02/28/cancer-drug-shortages/#comments</comments>
		<pubDate>Tue, 28 Feb 2012 19:47:32 +0000</pubDate>
		<dc:creator>Dr Cianfrocca</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[drug shortages]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1800</guid>
		<description><![CDATA[It seems as if every day brings a new shortage of an essential drug. In recent years, drug shortages have become increasingly common and put patients at risk as there are often no good alternatives to the affected drug. Oncology patients have been particularly impacted by these shortages as most chemotherapy agents as well as [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2012/02/28/cancer-drug-shortages/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>Catching Your Breath</title>
		<link>http://cancergrace.org/cancer-treatments/2012/02/17/dyspnea/</link>
		<comments>http://cancergrace.org/cancer-treatments/2012/02/17/dyspnea/#comments</comments>
		<pubDate>Fri, 17 Feb 2012 18:50:51 +0000</pubDate>
		<dc:creator>Dr Harman</dc:creator>
				<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[air hunger]]></category>
		<category><![CDATA[dyspnea]]></category>
		<category><![CDATA[shortness of breath]]></category>
		<category><![CDATA[SOB]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1720</guid>
		<description><![CDATA[Shortness of breath, air hunger, breathlessness, or the medical term dyspnea—all terms trying to capture one of the most unsettling feelings that a person can have.  That feeling that you are under water and need a snorkel.  The sensation of tightness in the chest and anxiety all wrapped up together.  That feeling of being “too [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2012/02/17/dyspnea/feed/</wfw:commentRss>
		<slash:comments>12</slash:comments>
		</item>
		<item>
		<title>Why Not Palliative Care?  Some thoughts on resistance…</title>
		<link>http://cancergrace.org/cancer-treatments/2011/10/26/why-not-palliative-care-some-thoughts-on-resistance%e2%80%a6/</link>
		<comments>http://cancergrace.org/cancer-treatments/2011/10/26/why-not-palliative-care-some-thoughts-on-resistance%e2%80%a6/#comments</comments>
		<pubDate>Wed, 26 Oct 2011 18:36:23 +0000</pubDate>
		<dc:creator>Dr Harman</dc:creator>
				<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Death and dying]]></category>
		<category><![CDATA[Hospice]]></category>
		<category><![CDATA[Palliative care]]></category>
		<category><![CDATA[terminal care]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1642</guid>
		<description><![CDATA[I consider GRACErs a very enlightened bunch regarding of palliative care, but outside of GRACE, there remains a lot of resistance to palliative care amongst patients, families, and oncologists (medical, surgical, radiation). Why? Why do people resist even the discussion of palliative care, even in the absence of end-of-life issues? Before I launch into further [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2011/10/26/why-not-palliative-care-some-thoughts-on-resistance%e2%80%a6/feed/</wfw:commentRss>
		<slash:comments>14</slash:comments>
		</item>
		<item>
		<title>The Black Box: Early Palliative Care in Metastatic NSCLC</title>
		<link>http://cancergrace.org/cancer-treatments/2011/10/12/the-black-box-early-palliative-care-in-metastatic-nsclc/</link>
		<comments>http://cancergrace.org/cancer-treatments/2011/10/12/the-black-box-early-palliative-care-in-metastatic-nsclc/#comments</comments>
		<pubDate>Wed, 12 Oct 2011 16:03:37 +0000</pubDate>
		<dc:creator>Dr Harman</dc:creator>
				<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Palliative care]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1638</guid>
		<description><![CDATA[In 2010, the world of lung cancer, and cancer in general, was abuzz with an intervention that improved quality of life and mood, and extended survival in patients with metastatic NSCLC. It was not a new chemotherapy or molecular biological agent. It was “early palliative care.” The original New England Journal of Medicine article several [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2011/10/12/the-black-box-early-palliative-care-in-metastatic-nsclc/feed/</wfw:commentRss>
		<slash:comments>5</slash:comments>
		</item>
		<item>
		<title>Q&amp;A Session with Dr. Mario Lacouture on Dermatologic Problems with Cancer Therapies</title>
		<link>http://cancergrace.org/cancer-treatments/2011/09/23/qa-mario-lacouture/</link>
		<comments>http://cancergrace.org/cancer-treatments/2011/09/23/qa-mario-lacouture/#comments</comments>
		<pubDate>Sat, 24 Sep 2011 00:06:57 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[dermatology]]></category>
		<category><![CDATA[Hair]]></category>
		<category><![CDATA[Nails]]></category>
		<category><![CDATA[Rash]]></category>
		<category><![CDATA[Skin]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1634</guid>
		<description><![CDATA[Following Dr. Lacouture&#8217;s presentation on management of skin, hair, and nail side effects of cancer treatments, we had a Q&#38;A session from the audience. This covered a lot of ground on a range of practical questions. Here&#8217;s the audio podcast from that program, along with the transcript: qa-dr-lacouture-on-skin-hair-nail-side-effects-of-treatment-transcript This was really all audio without associated [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2011/09/23/qa-mario-lacouture/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
<enclosure url="http://traffic.libsyn.com/cancergrace/GRACEcast-081_CA-Rx-Audio_Lacouture_Skin_QnA.mp3" length="17567859" type="audio/mpeg" />
			<itunes:keywords>dermatology,Hair,Nails,Rash,Skin</itunes:keywords>
	<itunes:subtitle>Following Dr. Lacouture&#039;s presentation on management of skin, hair, and nail side effects of cancer treatments, we had a Q&amp;A session from the audience.  This covered a lot of ground on a range of practical questions.</itunes:subtitle>
		<itunes:summary>Following Dr. Lacouture&#039;s presentation on management of skin, hair, and nail side effects of cancer treatments, we had a Q&amp;A session from the audience.  This covered a lot of ground on a range of practical questions.  Here&#039;s the audio podcast from that program, along with the transcript:

qa-dr-lacouture-on-skin-hair-nail-side-effects-of-treatment-transcript

This was really all audio without associated slides, so no figures or video version for this one.

Thanks again to LUNGevity Foundation for their partnership with GRACE in this program and the podcast. I hope it&#039;s helpful.</itunes:summary>
		<itunes:author>GRACE :: Treatments &amp; Symptom Management</itunes:author>
		<itunes:explicit>no</itunes:explicit>
		<itunes:duration>18:15</itunes:duration>
	</item>
		<item>
		<title>Dr. Mario Lacouture on Dermatologic Cancer Symptoms, and Side Effects of Treatment: Podcast Now Available</title>
		<link>http://cancergrace.org/cancer-treatments/2011/09/08/dr-mario-lacouture-on-dermatologic-cancer-symptoms-and-side-effects-of-treatment-podcast-now-available/</link>
		<comments>http://cancergrace.org/cancer-treatments/2011/09/08/dr-mario-lacouture-on-dermatologic-cancer-symptoms-and-side-effects-of-treatment-podcast-now-available/#comments</comments>
		<pubDate>Fri, 09 Sep 2011 02:43:58 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Rash and other side effects]]></category>
		<category><![CDATA[Supportive care]]></category>
		<category><![CDATA[dermatology]]></category>
		<category><![CDATA[Hair]]></category>
		<category><![CDATA[Nails]]></category>
		<category><![CDATA[Rash]]></category>
		<category><![CDATA[Skin]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1629</guid>
		<description><![CDATA[Several weeks ago, Dr. Mario Lacouture, a dermatologist now on faculty and running a busy clinic at Memorial Sloan-Kettering Cancer Center, joined us to do a webinar on Healthy Skin for People Living with Lung Cancer: Managing Dermatologic Symptoms and Side Effects&#8221;. I&#8217;m happy to now have the podcast from his presentation available, which is [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2011/09/08/dr-mario-lacouture-on-dermatologic-cancer-symptoms-and-side-effects-of-treatment-podcast-now-available/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
<enclosure url="http://traffic.libsyn.com/cancergrace/GRACEcast-080_CA-Rx-Video_Lacouture_on_Skin_Side_Effects.m4v" length="96782004" type="video/x-m4v" />
			<itunes:keywords>dermatology,Hair,Nails,Rash,Skin</itunes:keywords>
	<itunes:subtitle>Several weeks ago, Dr. Mario Lacouture, a dermatologist now on faculty and running a busy clinic at Memorial Sloan-Kettering Cancer Center, joined us to do a webinar on Healthy Skin for People Living with Lung Cancer: Managing Dermatologic Symptoms and...</itunes:subtitle>
		<itunes:summary>Several weeks ago, Dr. Mario Lacouture, a dermatologist now on faculty and running a busy clinic at Memorial Sloan-Kettering Cancer Center, joined us to do a webinar on Healthy Skin for People Living with Lung Cancer: Managing Dermatologic Symptoms and Side Effects&quot;.  I&#039;m happy to now have the podcast from his presentation available, which is actually modified from the original one, since some of the slides and the overall presentation wasn&#039;t as he wanted it to be, so he redid the recording and slides for the purposes of the podcast.  Therefore, for those who missed it, and even for those who attended, there should be new, practical information in there for you.  It covers prevention and treatment of problems involving skin, hair, and nails in cancer patients.

Below you&#039;ll find the audio and video versions of the podcast, as well as a pdf file of the transcript and figures that go with it.

dr-lacouture-on-skin-hair-nail-side-effects-of-treatment-audio-podcast

dr-lacouture-on-skin-hair-nail-side-effects-of-treatment-transcript

dr-lacouture-on-skin-hair-nail-side-effects-of-treatment-figures

 The live podcast was followed by a lively question and answer session, and we&#039;ll have that podcast available shortly.

Thanks to Dr. Lacouture for not only doing the live presentation but for taking the time to re-record a version he was happier with to offer to people as a resource.  And thanks, as always, to LUNGevity Foundation for partnering with us to make this series of live programs and podcasts possible.</itunes:summary>
		<itunes:author>GRACE :: Treatments &amp; Symptom Management</itunes:author>
		<itunes:explicit>no</itunes:explicit>
		<rawvoice:embed>&lt;iframe width=&quot;640&quot; height=&quot;480&quot; src=&quot;http://cancergrace.org/cancer-treatments/?powerpress_embed=1629-podcast&amp;amp;powerpress_player=html5video&quot; frameborder=&quot;0&quot; scrolling=&quot;no&quot;&gt;&lt;/iframe&gt;</rawvoice:embed>
	</item>
		<item>
		<title>Blood clots in Cancer: VTE and PE</title>
		<link>http://cancergrace.org/cancer-treatments/2011/05/29/blood-clots-in-cancer-vte-and-pe/</link>
		<comments>http://cancergrace.org/cancer-treatments/2011/05/29/blood-clots-in-cancer-vte-and-pe/#comments</comments>
		<pubDate>Sun, 29 May 2011 20:11:06 +0000</pubDate>
		<dc:creator>Dr. Weiss</dc:creator>
				<category><![CDATA[Supportive care]]></category>
		<category><![CDATA[clot]]></category>
		<category><![CDATA[PE]]></category>
		<category><![CDATA[pulmonary embolus]]></category>
		<category><![CDATA[VTE]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1607</guid>
		<description><![CDATA[What is a DVT and what is a PE? DVT stands for deep vein thrombosis. “Thrombosis” is the doctorly word for, “clot,” and the deep veins are the larger veins of the legs and arms. DVTs can disrupt the flow of blood from an extremity (arm or leg) causing swelling and pain. This is most [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2011/05/29/blood-clots-in-cancer-vte-and-pe/feed/</wfw:commentRss>
		<slash:comments>11</slash:comments>
		</item>
		<item>
		<title>Slim Chance vs. No Chance: Why the Hero Jumps off a Cliff</title>
		<link>http://cancergrace.org/cancer-treatments/2011/05/22/jumping-off-a-cliff/</link>
		<comments>http://cancergrace.org/cancer-treatments/2011/05/22/jumping-off-a-cliff/#comments</comments>
		<pubDate>Sun, 22 May 2011 21:25:14 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[coping with cancer]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1603</guid>
		<description><![CDATA[Sometimes we find ourselves in a situation in cancer treatment where the choice of treatment options is almost the lesser of two evils. For instance, a few months ago, a patient with locally advanced non-small cell lung cancer (NSCLC) showed little or no response to treatment with chemo and concurrent chest radiation that was intended [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2011/05/22/jumping-off-a-cliff/feed/</wfw:commentRss>
		<slash:comments>12</slash:comments>
		</item>
		<item>
		<title>Febrile Neutropenia, Part II: Prevention and Treatment</title>
		<link>http://cancergrace.org/cancer-treatments/2011/05/13/f-and-n-part-i/</link>
		<comments>http://cancergrace.org/cancer-treatments/2011/05/13/f-and-n-part-i/#comments</comments>
		<pubDate>Fri, 13 May 2011 18:41:40 +0000</pubDate>
		<dc:creator>Dr. Weiss</dc:creator>
				<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Supportive care]]></category>
		<category><![CDATA[febrile neutropenia]]></category>
		<category><![CDATA[fever]]></category>
		<category><![CDATA[fever and neutropenia]]></category>
		<category><![CDATA[neutropenia]]></category>
		<category><![CDATA[neutrophil]]></category>
		<category><![CDATA[weiss]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1591</guid>
		<description><![CDATA[Preventing F &#38; N There are three basic ways to prevent febrile neutropenia. When appropriate, a regimen with a smaller chance of causing F &#38; N can be chosen. There are two other options: the use of drugs to bring the neutrophil count up, and prophylactic (preventative) antibiotics. There are two drugs in common usage [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2011/05/13/f-and-n-part-i/feed/</wfw:commentRss>
		<slash:comments>7</slash:comments>
		</item>
		<item>
		<title>Febrile Neutropenia, Part I: The side effect of chemotherapy your doctor (probably) worries about the most</title>
		<link>http://cancergrace.org/cancer-treatments/2011/05/11/f-n-the-side-effect-of-chemotherapy-your-doctor-probably-worries-about-the-most%e2%80%94part-1/</link>
		<comments>http://cancergrace.org/cancer-treatments/2011/05/11/f-n-the-side-effect-of-chemotherapy-your-doctor-probably-worries-about-the-most%e2%80%94part-1/#comments</comments>
		<pubDate>Wed, 11 May 2011 14:40:48 +0000</pubDate>
		<dc:creator>Dr. Weiss</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Supportive care]]></category>
		<category><![CDATA[F&N]]></category>
		<category><![CDATA[febrile neutropenia]]></category>
		<category><![CDATA[fever and neutropenia]]></category>
		<category><![CDATA[infection]]></category>
		<category><![CDATA[neutropenia]]></category>
		<category><![CDATA[neutrophil]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1535</guid>
		<description><![CDATA[Introduction I have asked many patients what side effect of chemotherapy they fear the most. The most common answer is nausea, very closely followed by fatigue (or its cousins such as feeling, “blah,” or the consequences of fatigue such as not being able to do things). I’ve never asked the question of another oncologist, but [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2011/05/11/f-n-the-side-effect-of-chemotherapy-your-doctor-probably-worries-about-the-most%e2%80%94part-1/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>FAQ: What might I expect to happen when someone I&#8217;m caring for is dying?</title>
		<link>http://cancergrace.org/cancer-treatments/2011/05/06/faq-dying-process/</link>
		<comments>http://cancergrace.org/cancer-treatments/2011/05/06/faq-dying-process/#comments</comments>
		<pubDate>Fri, 06 May 2011 23:36:02 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Death and dying]]></category>
		<category><![CDATA[Hospice]]></category>
		<category><![CDATA[Palliative care]]></category>
		<category><![CDATA[terminal care]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1532</guid>
		<description><![CDATA[This is a difficult topic for many people to think about, and especially to bring up in a public forum, but people still want and need to know what they might expect as they or someone they care for are declining. It is understandable to fear the unknown, and to fear suffering. I would say [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2011/05/06/faq-dying-process/feed/</wfw:commentRss>
		<slash:comments>13</slash:comments>
		</item>
		<item>
		<title>Hoarseness</title>
		<link>http://cancergrace.org/cancer-treatments/2011/04/16/hoarseness/</link>
		<comments>http://cancergrace.org/cancer-treatments/2011/04/16/hoarseness/#comments</comments>
		<pubDate>Sat, 16 Apr 2011 15:05:33 +0000</pubDate>
		<dc:creator>Dr. Weiss</dc:creator>
				<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Supportive care]]></category>
		<category><![CDATA[Dr. Weiss]]></category>
		<category><![CDATA[hoarse]]></category>
		<category><![CDATA[hoarseness]]></category>
		<category><![CDATA[medialization]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1470</guid>
		<description><![CDATA[Hoarseness Introduction Thank you to cross-bearer for asking about hoarseness. Hoarseness is any change in voice quality. Most commonly, it is experienced as decreased volume with increased strain. It’s a common problem in lung cancer patients, so common that we’ve discussed it over 40 times in the forums and so I think that it may [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2011/04/16/hoarseness/feed/</wfw:commentRss>
		<slash:comments>7</slash:comments>
		</item>
		<item>
		<title>Glamorous Topics in Cancer Symptoms: Diarrhea</title>
		<link>http://cancergrace.org/cancer-treatments/2011/04/08/glamorous-topics-in-cancer-symptoms-diarrhea/</link>
		<comments>http://cancergrace.org/cancer-treatments/2011/04/08/glamorous-topics-in-cancer-symptoms-diarrhea/#comments</comments>
		<pubDate>Fri, 08 Apr 2011 18:20:36 +0000</pubDate>
		<dc:creator>Dr Harman</dc:creator>
				<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Diarrhea]]></category>
		<category><![CDATA[Symptom Management]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1456</guid>
		<description><![CDATA[Somehow, I have done a quite a few posts on glamorous topics, like nausea/vomiting and constipation. Less common than constipation but still very troublesome is constipation’s bedfellow, diarrhea. For patients who have cancer, diarrhea can arise due to multiple reasons, both due to the disease itself and treatment. Sometimes diarrhea and constipation end up being [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2011/04/08/glamorous-topics-in-cancer-symptoms-diarrhea/feed/</wfw:commentRss>
		<slash:comments>5</slash:comments>
		</item>
		<item>
		<title>Is Palliative Care Right for You?</title>
		<link>http://cancergrace.org/cancer-treatments/2011/03/28/is-palliative-care-right-for-you/</link>
		<comments>http://cancergrace.org/cancer-treatments/2011/03/28/is-palliative-care-right-for-you/#comments</comments>
		<pubDate>Tue, 29 Mar 2011 02:35:24 +0000</pubDate>
		<dc:creator>Dr Ramchandran</dc:creator>
				<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Palliative care]]></category>
		<category><![CDATA[Supportive care]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1446</guid>
		<description><![CDATA[In August of 2010, Jennifer Temel and colleagues published an article in the NEJM that showed that palliative care improves quality of life, symptoms, end of life care, and &#8212; lo and behold &#8212; overall survival. The survival benefit seen with the early intervention of palliative care for metastatic NSCLC patients was approximately 2 months, [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2011/03/28/is-palliative-care-right-for-you/feed/</wfw:commentRss>
		<slash:comments>5</slash:comments>
		</item>
		<item>
		<title>What is Hospice: Fact and Fiction</title>
		<link>http://cancergrace.org/cancer-treatments/2011/03/10/what-is-hospice-fact-and-fiction/</link>
		<comments>http://cancergrace.org/cancer-treatments/2011/03/10/what-is-hospice-fact-and-fiction/#comments</comments>
		<pubDate>Fri, 11 Mar 2011 02:20:35 +0000</pubDate>
		<dc:creator>Dr Ramchandran</dc:creator>
				<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Hospice]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1442</guid>
		<description><![CDATA[Hospice is both an organization and a philosophy of care. It was first conceptualized in the United Kingdom in 1967 by Dame Cicely Saunders who was a nurse, physician and social worker. She advocated for a multidisciplinary approach to the care of people with advanced illness with a focus not only on the physical, but [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2011/03/10/what-is-hospice-fact-and-fiction/feed/</wfw:commentRss>
		<slash:comments>6</slash:comments>
		</item>
		<item>
		<title>Mucositis: New therapies for an old complication?</title>
		<link>http://cancergrace.org/cancer-treatments/2011/03/04/mucositis-rx/</link>
		<comments>http://cancergrace.org/cancer-treatments/2011/03/04/mucositis-rx/#comments</comments>
		<pubDate>Fri, 04 Mar 2011 22:59:04 +0000</pubDate>
		<dc:creator>Dr Ramchandran</dc:creator>
				<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Mucositis]]></category>
		<category><![CDATA[Side Effects]]></category>
		<category><![CDATA[Stomatitis]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1432</guid>
		<description><![CDATA[Mucositis is commonly seen in high dose chemotherapy protocols for hematologic malignancies (ie conditioning or induction regimens for leukemia), or aggressive chemo-radiation for head and neck cancers. It is a term physicians use to describe a wide range of oral complications related to cancer treatment.This may include redness, pain, ulceration, swelling and surface lesions (pseudomembrane, [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2011/03/04/mucositis-rx/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>Why do we fall so short with hospice care in the US?</title>
		<link>http://cancergrace.org/cancer-treatments/2011/01/19/why-do-we-fall-so-short-with-hospice-care-in-the-us/</link>
		<comments>http://cancergrace.org/cancer-treatments/2011/01/19/why-do-we-fall-so-short-with-hospice-care-in-the-us/#comments</comments>
		<pubDate>Wed, 19 Jan 2011 20:08:33 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Hospice]]></category>
		<category><![CDATA[Palliative care]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1422</guid>
		<description><![CDATA[I am a great fan of hospice services and feel that it&#8217;s a terrible shortcoming of the US health care system, and particularly our management of cancer care, that hospice is so underutilized and typically delayed until a terminally ill patient is within their last few days of life. Hospice care is meant to be [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2011/01/19/why-do-we-fall-so-short-with-hospice-care-in-the-us/feed/</wfw:commentRss>
		<slash:comments>7</slash:comments>
		</item>
		<item>
		<title>Is there a harm in discontinuing Avastin (bevacizumab)? The evidence says no.</title>
		<link>http://cancergrace.org/cancer-treatments/2010/12/05/is-there-a-harm-in-discontinuing-avastin-bevacizumab-the-evidence-says-no/</link>
		<comments>http://cancergrace.org/cancer-treatments/2010/12/05/is-there-a-harm-in-discontinuing-avastin-bevacizumab-the-evidence-says-no/#comments</comments>
		<pubDate>Mon, 06 Dec 2010 02:21:35 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Anti-angiogenic agents]]></category>
		<category><![CDATA[Targeted therapies]]></category>
		<category><![CDATA[Angi-angiogenic therapy]]></category>
		<category><![CDATA[Angiogensis]]></category>
		<category><![CDATA[Avastin]]></category>
		<category><![CDATA[Bevacizumab]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1412</guid>
		<description><![CDATA[One question that has emerged with the increasing use of anti-angiogenic (blood vessel-inhibiting) therapy like Avastin (bevacizumab) for many different kinds of cancer is whether, as some lab-based research has suggested, the removal of the anti-angiogenic effect when the agent is discontinued leads to a rebound increase in pro-angiogenic signaling. If that happens, perhaps it [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2010/12/05/is-there-a-harm-in-discontinuing-avastin-bevacizumab-the-evidence-says-no/feed/</wfw:commentRss>
		<slash:comments>1</slash:comments>
		</item>
		<item>
		<title>XGEVA (Denosumab) Approved as Treatment for Preventing Skeletal-Related Complications</title>
		<link>http://cancergrace.org/cancer-treatments/2010/11/29/xgeva-denosumab-for-sres/</link>
		<comments>http://cancergrace.org/cancer-treatments/2010/11/29/xgeva-denosumab-for-sres/#comments</comments>
		<pubDate>Tue, 30 Nov 2010 05:19:57 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Management of Bone Metastases]]></category>
		<category><![CDATA[Bone Metastases]]></category>
		<category><![CDATA[Denosumab]]></category>
		<category><![CDATA[Skeletal Metastases]]></category>
		<category><![CDATA[SREs. Skeletal-Related Events]]></category>
		<category><![CDATA[XGEVA]]></category>
		<category><![CDATA[zoledronic acid]]></category>
		<category><![CDATA[zometa]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1402</guid>
		<description><![CDATA[The FDA just recently approved a new drug, denosumab (now christened with the marketed name XGEVA) as a treatment for patients with bone metastases from solid tumors such as lung cancer, breast cancer, and prostate cancer (in fact about three quarters of bone metastases are in these three cancer types). Dr. Sanborn previously described preliminary [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2010/11/29/xgeva-denosumab-for-sres/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>Major Report on End of Life Care in US Highlights Shortfalls vs. Optimal Care</title>
		<link>http://cancergrace.org/cancer-treatments/2010/11/17/dartmouth-atlas-report-on-end-of-life-care/</link>
		<comments>http://cancergrace.org/cancer-treatments/2010/11/17/dartmouth-atlas-report-on-end-of-life-care/#comments</comments>
		<pubDate>Thu, 18 Nov 2010 01:53:48 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[General]]></category>
		<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[End of Life Care]]></category>
		<category><![CDATA[Hospice]]></category>
		<category><![CDATA[Palliative care]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1392</guid>
		<description><![CDATA[The Dartmouth Atlas Project is a nonprofit organization that studies patterns of medical care and use of resources in the US. Yesterday, they released the report of a large study of end of life care for cancer patients in the US, and it highlighted some rather striking findings (many pages, but largely graphics, and a [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2010/11/17/dartmouth-atlas-report-on-end-of-life-care/feed/</wfw:commentRss>
		<slash:comments>5</slash:comments>
		</item>
		<item>
		<title>Is Palliative Care &#8220;Giving Up&#8221;? No, It Can Actually Improve Both Quality of Life AND Survival</title>
		<link>http://cancergrace.org/cancer-treatments/2010/07/30/is-palliative-care-giving-up/</link>
		<comments>http://cancergrace.org/cancer-treatments/2010/07/30/is-palliative-care-giving-up/#comments</comments>
		<pubDate>Fri, 30 Jul 2010 23:26:48 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[DNR/DNI]]></category>
		<category><![CDATA[End of Life Care]]></category>
		<category><![CDATA[Hospice]]></category>
		<category><![CDATA[Palliative care]]></category>
		<category><![CDATA[Supportive care]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1356</guid>
		<description><![CDATA[GRACE member and forum moderator Catharine started a forum thread and conversation that followed a great link to a difficult but thought-provoking article written by Dr. Atul Gawande in the New Yorker on the subject of the transition from aggressive anti-cancer therapy to a focus on palliating symptoms and focusing on quality of life. This [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2010/07/30/is-palliative-care-giving-up/feed/</wfw:commentRss>
		<slash:comments>13</slash:comments>
		</item>
		<item>
		<title>Cancer Treatments with Big Benefits for Small Populations</title>
		<link>http://cancergrace.org/cancer-treatments/2010/06/13/big-benefits-in-small-populations/</link>
		<comments>http://cancergrace.org/cancer-treatments/2010/06/13/big-benefits-in-small-populations/#comments</comments>
		<pubDate>Sun, 13 Jun 2010 19:34:14 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Cancer 101]]></category>
		<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[General]]></category>
		<category><![CDATA[ALK Rearrangement]]></category>
		<category><![CDATA[Avastin]]></category>
		<category><![CDATA[Bevacizumab]]></category>
		<category><![CDATA[crizotinib]]></category>
		<category><![CDATA[PF-02341066]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1344</guid>
		<description><![CDATA[Earlier this week, I wrote about the very promising early work with the novel, still investigational agent crizotinib (PF-02341066) in treating the 4-5% of NSCLC patients with a tumor positive for an ALK rearrangement. For this minority of patients, the benefit was of a kind we don&#8217;t see enough in cancer and certainly not in [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2010/06/13/big-benefits-in-small-populations/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>Getting Your Z’s with Cancer</title>
		<link>http://cancergrace.org/cancer-treatments/2010/02/09/getting-your-z%e2%80%99s-with-cancer/</link>
		<comments>http://cancergrace.org/cancer-treatments/2010/02/09/getting-your-z%e2%80%99s-with-cancer/#comments</comments>
		<pubDate>Tue, 09 Feb 2010 07:04:11 +0000</pubDate>
		<dc:creator>Dr Harman</dc:creator>
				<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[insomnia]]></category>
		<category><![CDATA[Sleep]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1330</guid>
		<description><![CDATA[Sleep is a precious commodity. While sleep disturbances in cancer patients include both insomnia as well as other sleep disorders (like sleep apnea), I will focus primarily on insomnia and the lack of sleep in this post, as that is by far the most common problem. Sleep disorders are more prevalent in patients with cancer [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2010/02/09/getting-your-z%e2%80%99s-with-cancer/feed/</wfw:commentRss>
		<slash:comments>5</slash:comments>
		</item>
		<item>
		<title>Anxiety in Cancer: Not Just the Jitters</title>
		<link>http://cancergrace.org/cancer-treatments/2010/01/19/anxiety-in-cancer-not-just-the-jitters/</link>
		<comments>http://cancergrace.org/cancer-treatments/2010/01/19/anxiety-in-cancer-not-just-the-jitters/#comments</comments>
		<pubDate>Tue, 19 Jan 2010 15:12:27 +0000</pubDate>
		<dc:creator>Dr Harman</dc:creator>
				<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Anxiety]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1318</guid>
		<description><![CDATA[Anxiety is common in patients with cancer and can develop as a result of cancer and its treatments. Symptoms of anxiety are seen in up to 48% of all cancer patients, often in the form of a “situational anxiety”—these symptoms include worry as well as physical symptoms like muscle tension, restlessness, palpitations, sweating, and shortness [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2010/01/19/anxiety-in-cancer-not-just-the-jitters/feed/</wfw:commentRss>
		<slash:comments>8</slash:comments>
		</item>
		<item>
		<title>Depression in Cancer: Does it come with the territory?</title>
		<link>http://cancergrace.org/cancer-treatments/2010/01/09/depression-in-cance/</link>
		<comments>http://cancergrace.org/cancer-treatments/2010/01/09/depression-in-cance/#comments</comments>
		<pubDate>Sat, 09 Jan 2010 14:01:03 +0000</pubDate>
		<dc:creator>Dr Harman</dc:creator>
				<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Depression]]></category>
		<category><![CDATA[Symptom Management]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1312</guid>
		<description><![CDATA[People often expect that having cancer would make anyone depressed, that it is “normal,” but clinical depression is anything but normal and is imminently treatable. The challenge is that cancer can often cause the same symptoms that are seen in depression, so that depression is under-recognized and consequently undertreated. What is depression? It is a [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2010/01/09/depression-in-cance/feed/</wfw:commentRss>
		<slash:comments>4</slash:comments>
		</item>
		<item>
		<title>Palliative What?</title>
		<link>http://cancergrace.org/cancer-treatments/2010/01/04/palliative-what/</link>
		<comments>http://cancergrace.org/cancer-treatments/2010/01/04/palliative-what/#comments</comments>
		<pubDate>Mon, 04 Jan 2010 16:52:25 +0000</pubDate>
		<dc:creator>Dr Harman</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Hospice]]></category>
		<category><![CDATA[Palliative care]]></category>
		<category><![CDATA[Supportive care]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1306</guid>
		<description><![CDATA[What is palliative care? I get this question at least once a day, not only from patients and families but also from other clinicians. While many GRACE members are familiar with palliative care, there still exists a lot of confusion out there about what palliative care exactly is. To be honest, back when I started [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2010/01/04/palliative-what/feed/</wfw:commentRss>
		<slash:comments>5</slash:comments>
		</item>
		<item>
		<title>High Blood Pressure and Anti-Angiogenic Therapy: A Beneficial Side Effect?</title>
		<link>http://cancergrace.org/cancer-treatments/2009/10/20/htn-and-antiangiogenic-rx/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/10/20/htn-and-antiangiogenic-rx/#comments</comments>
		<pubDate>Wed, 21 Oct 2009 04:59:06 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Anti-angiogenic agents]]></category>
		<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Avastin]]></category>
		<category><![CDATA[Bevacizumab]]></category>
		<category><![CDATA[Hypertension]]></category>
		<category><![CDATA[Nexavar]]></category>
		<category><![CDATA[Sorafenib]]></category>
		<category><![CDATA[Sunitinib]]></category>
		<category><![CDATA[Sutent]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1294</guid>
		<description><![CDATA[One of the most common side effects of many different anti-angiogenic agents, which are felt to decrease the tumor&#8217;s blood supply, is high blood pressure, also known as hypertension. The cause of this isn&#8217;t really known, but most patients develop some degree of high blood pressure. What is interesting is that there is growing evidence [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/10/20/htn-and-antiangiogenic-rx/feed/</wfw:commentRss>
		<slash:comments>8</slash:comments>
		</item>
		<item>
		<title>Highlights of Attempts at Prevention and Treatment of Chemo-Induced Peripheral Neuropathy</title>
		<link>http://cancergrace.org/cancer-treatments/2009/10/11/prevention-treatment-cip/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/10/11/prevention-treatment-cip/#comments</comments>
		<pubDate>Sun, 11 Oct 2009 23:09:51 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[neuropathic pain]]></category>
		<category><![CDATA[neuropathy]]></category>
		<category><![CDATA[peripheral neuropathy]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1280</guid>
		<description><![CDATA[Chemotherapy is a common contributor to peripheral neuropathy, and because of this, there have been efforts to both prevent and treat chemo-induced peripheral neuropathy (CIPN). However, much of the work in this field has been hampered by difficulty in measuring this, as well as trials that are pretty small. A couple have been the subject [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/10/11/prevention-treatment-cip/feed/</wfw:commentRss>
		<slash:comments>3</slash:comments>
		</item>
		<item>
		<title>Chemotherapy-Induced Peripheral Neuropathy</title>
		<link>http://cancergrace.org/cancer-treatments/2009/10/05/chemotherapy-induced-peripheral-neuropathy/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/10/05/chemotherapy-induced-peripheral-neuropathy/#comments</comments>
		<pubDate>Tue, 06 Oct 2009 05:26:57 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[cisplatin]]></category>
		<category><![CDATA[navelbine]]></category>
		<category><![CDATA[neuropathy]]></category>
		<category><![CDATA[paclitaxel]]></category>
		<category><![CDATA[peripheral neuropathy]]></category>
		<category><![CDATA[taxol]]></category>
		<category><![CDATA[vinorelbine]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1273</guid>
		<description><![CDATA[Peripheral neuropathy is a common complication of multiple widely used chemotherapy agents, and this symptom often limits our ability to have patients continue on the same treatment, even when it&#8217;s effectively treating the cancer. Typically, the symptoms are more sensory than motor, and the leading complaints are numbness and tingling, cold sensitivity, sometimes burning, electric, [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/10/05/chemotherapy-induced-peripheral-neuropathy/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>Neuropathy in Cancer: That Tingling Feeling That Isn&#8217;t Love</title>
		<link>http://cancergrace.org/cancer-treatments/2009/10/03/neuropathy-intr/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/10/03/neuropathy-intr/#comments</comments>
		<pubDate>Sun, 04 Oct 2009 03:48:39 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[neuropathy]]></category>
		<category><![CDATA[peripheral neuropathy]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1265</guid>
		<description><![CDATA[Neuropathy, also known as peripheral neuropathy, is a common medical problem caused by damage and dysfunction to one or more peripheral nerves, which are the nerves connecting the brain and spinal cord to the rest of the body. There are three different types of nerves: sensory, motor, and autonomic (controlling reflexive/automatic body processes like blood [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/10/03/neuropathy-intr/feed/</wfw:commentRss>
		<slash:comments>3</slash:comments>
		</item>
		<item>
		<title>Bone Pain in Cancer</title>
		<link>http://cancergrace.org/cancer-treatments/2009/07/26/bone-pain-in-cancer/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/07/26/bone-pain-in-cancer/#comments</comments>
		<pubDate>Mon, 27 Jul 2009 03:46:07 +0000</pubDate>
		<dc:creator>Dr Harman</dc:creator>
				<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[Supportive care]]></category>
		<category><![CDATA[Bone Metastases]]></category>
		<category><![CDATA[Bone pain]]></category>
		<category><![CDATA[cancer-related pain]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1255</guid>
		<description><![CDATA[Bone pain is a specific cancer pain syndrome that also happens to be the most common cause of cancer pain. Cancer involvement of bone is also something that can be seen with numerous types of cancer. It is a type of somatic pain, which is “body-related” pain, as I mentioned in my Pain 101 post. [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/07/26/bone-pain-in-cancer/feed/</wfw:commentRss>
		<slash:comments>14</slash:comments>
		</item>
		<item>
		<title>Cancer-related Neuropathic Pain</title>
		<link>http://cancergrace.org/cancer-treatments/2009/07/19/cancer-related-neuropathic-pain/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/07/19/cancer-related-neuropathic-pain/#comments</comments>
		<pubDate>Sun, 19 Jul 2009 20:01:15 +0000</pubDate>
		<dc:creator>Dr Harman</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Pain and Symptom Management]]></category>
		<category><![CDATA[cancer-related pain]]></category>
		<category><![CDATA[neuropathic pain]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1243</guid>
		<description><![CDATA[Neuropathic pain is a common pain syndrome for patients with cancer. As I mentioned in my introductory pain post, neuropathic pain is one of the three main types of pain (somatic, visceral, and neuropathic). It is nerve-related and is typically described as an electrical or burning sensation; it can occur both due to damaged peripheral [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/07/19/cancer-related-neuropathic-pain/feed/</wfw:commentRss>
		<slash:comments>7</slash:comments>
		</item>
		<item>
		<title>Opioids 101, And Opioid Myths</title>
		<link>http://cancergrace.org/cancer-treatments/2009/07/11/opioids-101-opioid-myths/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/07/11/opioids-101-opioid-myths/#comments</comments>
		<pubDate>Sat, 11 Jul 2009 16:44:43 +0000</pubDate>
		<dc:creator>Dr Harman</dc:creator>
				<category><![CDATA[Cancer 101]]></category>
		<category><![CDATA[Supportive care]]></category>
		<category><![CDATA[addiction]]></category>
		<category><![CDATA[cancer-related pain]]></category>
		<category><![CDATA[dependence]]></category>
		<category><![CDATA[narcotics]]></category>
		<category><![CDATA[opioids]]></category>
		<category><![CDATA[Pain]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1235</guid>
		<description><![CDATA[Opioids are a class of pain medications that are frequently used for cancer-related pain, and for good reason. They target the opioid receptors, which are found throughout our body and effect pain transmission in the nervous system, from our peripheral nerves all the way to the brain. Of note, our bodies make natural opioids—you may [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/07/11/opioids-101-opioid-myths/feed/</wfw:commentRss>
		<slash:comments>10</slash:comments>
		</item>
		<item>
		<title>Cancer Pain 101</title>
		<link>http://cancergrace.org/cancer-treatments/2009/07/02/cancer-pain-101/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/07/02/cancer-pain-101/#comments</comments>
		<pubDate>Thu, 02 Jul 2009 18:20:11 +0000</pubDate>
		<dc:creator>Dr Harman</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Supportive care]]></category>
		<category><![CDATA[cancer-related pain]]></category>
		<category><![CDATA[neuropathic pain]]></category>
		<category><![CDATA[neuropathy]]></category>
		<category><![CDATA[Pain]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1223</guid>
		<description><![CDATA[In reviewing posts from GRACE, it&#8217;s not surprising to see that pain is major issue for many patients with cancer. Pain is not unique to cancer, but for most patients with cancer, their pain is related to the cancer in some way. In cancer, the causes of pain not only include the disease itself, but [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/07/02/cancer-pain-101/feed/</wfw:commentRss>
		<slash:comments>5</slash:comments>
		</item>
		<item>
		<title>Cancer-Related Constipation</title>
		<link>http://cancergrace.org/cancer-treatments/2009/06/02/cancer-related-constipation/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/06/02/cancer-related-constipation/#comments</comments>
		<pubDate>Wed, 03 Jun 2009 02:37:42 +0000</pubDate>
		<dc:creator>Dr Harman</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Supportive care]]></category>
		<category><![CDATA[bisacodyl]]></category>
		<category><![CDATA[colace]]></category>
		<category><![CDATA[Constipation]]></category>
		<category><![CDATA[docusate]]></category>
		<category><![CDATA[dulcolax]]></category>
		<category><![CDATA[magnesium citrate]]></category>
		<category><![CDATA[metamucil]]></category>
		<category><![CDATA[methylnaltrexone]]></category>
		<category><![CDATA[miralax]]></category>
		<category><![CDATA[Opioid-Induced Constipation]]></category>
		<category><![CDATA[polyethlylene glycol]]></category>
		<category><![CDATA[Relistor]]></category>
		<category><![CDATA[senna]]></category>
		<category><![CDATA[senokot]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/?p=1207</guid>
		<description><![CDATA[Constipation…not the most glamorous topic, but it is downright unpleasant to have and can become severe enough to greatly impact quality of life. It is not a problem unique to patients with cancer, but millions of people suffer from chronic constipation in the U.S. As bowel habits vary from individual to individual, there has been [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/06/02/cancer-related-constipation/feed/</wfw:commentRss>
		<slash:comments>4</slash:comments>
		</item>
		<item>
		<title>Cancer and Nausea, Part II: Non-CINV Nausea and Treatment Strategies</title>
		<link>http://cancergrace.org/cancer-treatments/2009/05/22/cancer-nausea-pt-ii/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/05/22/cancer-nausea-pt-ii/#comments</comments>
		<pubDate>Fri, 22 May 2009 21:45:07 +0000</pubDate>
		<dc:creator>Dr Harman</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Miscellaneous Other Problems from Lung Cancer]]></category>
		<category><![CDATA[Supportive care]]></category>
		<category><![CDATA[5-HT3 antagonist]]></category>
		<category><![CDATA[anzemet]]></category>
		<category><![CDATA[CINV]]></category>
		<category><![CDATA[compazine]]></category>
		<category><![CDATA[dolasetron]]></category>
		<category><![CDATA[emend]]></category>
		<category><![CDATA[granisetron]]></category>
		<category><![CDATA[kytril]]></category>
		<category><![CDATA[marinol]]></category>
		<category><![CDATA[nausea]]></category>
		<category><![CDATA[ondansetron]]></category>
		<category><![CDATA[phenergan]]></category>
		<category><![CDATA[reglan]]></category>
		<category><![CDATA[steroids]]></category>
		<category><![CDATA[vomiting]]></category>
		<category><![CDATA[zofran]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/2009/05/22/cancer-nausea-pt-ii/</guid>
		<description><![CDATA[Nausea is a very complex symptom involving numerous pathways between the brain and the gut, and it can have many different causes. While chemotherapy is a big culprit in causing nausea and vomiting, there are multiple other causes unique to cancer. Here are few that stand out: * Radiation-induced nausea and vomiting occurs when a [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/05/22/cancer-nausea-pt-ii/feed/</wfw:commentRss>
		<slash:comments>4</slash:comments>
		</item>
		<item>
		<title>Cancer and Nausea, Part I: Chemotherapy-Induced Nausea and Vomiting (CINV)</title>
		<link>http://cancergrace.org/cancer-treatments/2009/05/19/cinv/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/05/19/cinv/#comments</comments>
		<pubDate>Tue, 19 May 2009 14:22:35 +0000</pubDate>
		<dc:creator>Dr Harman</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[5-HT3 antagonist]]></category>
		<category><![CDATA[alozi]]></category>
		<category><![CDATA[anzemet]]></category>
		<category><![CDATA[aprepitant]]></category>
		<category><![CDATA[CINV]]></category>
		<category><![CDATA[dolasetron]]></category>
		<category><![CDATA[emend]]></category>
		<category><![CDATA[granisetron]]></category>
		<category><![CDATA[kytril]]></category>
		<category><![CDATA[nausea]]></category>
		<category><![CDATA[NK1 antagonist]]></category>
		<category><![CDATA[ondansetron]]></category>
		<category><![CDATA[palonosetron]]></category>
		<category><![CDATA[vomiting]]></category>
		<category><![CDATA[zofran]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/2009/05/19/cinv/</guid>
		<description><![CDATA[While nausea and vomiting are common symptoms for many patients, patient with cancer often have multiple contributing factors for their nausea, not only from the disease itself but from the treatments. This two-part post will be looking at nausea and vomiting specifically with an eye towards cancer, the first part on chemotherapy-induced nausea and vomiting [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/05/19/cinv/feed/</wfw:commentRss>
		<slash:comments>5</slash:comments>
		</item>
		<item>
		<title>Ginger Root for Nausea</title>
		<link>http://cancergrace.org/cancer-treatments/2009/05/16/ginger-root-for-nausea/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/05/16/ginger-root-for-nausea/#comments</comments>
		<pubDate>Sat, 16 May 2009 15:53:11 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[ASCO]]></category>
		<category><![CDATA[cancer]]></category>
		<category><![CDATA[Chemotherapy]]></category>
		<category><![CDATA[ginger]]></category>
		<category><![CDATA[ginger root]]></category>
		<category><![CDATA[nausea]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/2009/05/16/ginger-root-for-nausea/</guid>
		<description><![CDATA[The details will be presented at the upcoming ASCO annual meeting two weeks from now, but there&#8217;s a preliminary highlight released that ginger root capsules can produce a very significant reduction in chemotherapy-induced nausea. This work validates the general recommendation to take ginger ale for an upset stomach, etc., but it&#8217;s important to note that [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/05/16/ginger-root-for-nausea/feed/</wfw:commentRss>
		<slash:comments>3</slash:comments>
		</item>
		<item>
		<title>Managing Cough: Common and Challenging Problem</title>
		<link>http://cancergrace.org/cancer-treatments/2009/05/09/managing-cough/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/05/09/managing-cough/#comments</comments>
		<pubDate>Sat, 09 May 2009 16:05:53 +0000</pubDate>
		<dc:creator>Dr Harman</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Symptom Management]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/2009/05/09/managing-cough/</guid>
		<description><![CDATA[I’ve noticed some postings on cough and wanted to talk a little more about it. It is certainly a troublesome and common symptom for patients with cancer, but it is also a common symptom reported for any patient going to see their primary care doctor. Cough, believe it or not, is a reflex designed to [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/05/09/managing-cough/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>An Overview of Cancer-Related Fatigue</title>
		<link>http://cancergrace.org/cancer-treatments/2009/05/01/cancer-related-fatigue/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/05/01/cancer-related-fatigue/#comments</comments>
		<pubDate>Fri, 01 May 2009 17:13:39 +0000</pubDate>
		<dc:creator>Dr Harman</dc:creator>
				<category><![CDATA[Cancer 101]]></category>
		<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Cancer-Related Fatigue]]></category>
		<category><![CDATA[Fatigue]]></category>
		<category><![CDATA[methylphenidate]]></category>
		<category><![CDATA[modafanil]]></category>
		<category><![CDATA[provigil]]></category>
		<category><![CDATA[ritalin]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/2009/05/01/cancer-related-fatigue/</guid>
		<description><![CDATA[Fatigue is one of the most common symptoms for patients with cancer, reported in up to 90% of patients undergoing chemotherapy or radiation therapy. Patients who are cancer survivors can still be affected by fatigue months to even years out from their last treatment. Cancer-related fatigue (CRF) specifically refers to the distressing tiredness or decreased [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/05/01/cancer-related-fatigue/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Low Dose Naltrexone (LDN): Miracle Cure or “Why Not” Drug?</title>
		<link>http://cancergrace.org/cancer-treatments/2009/04/04/ldn-miracle-or-no/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/04/04/ldn-miracle-or-no/#comments</comments>
		<pubDate>Sat, 04 Apr 2009 06:52:27 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Bihari]]></category>
		<category><![CDATA[CAM]]></category>
		<category><![CDATA[cancer]]></category>
		<category><![CDATA[DCA]]></category>
		<category><![CDATA[dichloroacetate]]></category>
		<category><![CDATA[LDN]]></category>
		<category><![CDATA[miracle cure]]></category>
		<category><![CDATA[naltrexone]]></category>
		<category><![CDATA[zagon]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/2009/04/04/low-dose-naltrexone-ldn-miracle-cure-or-%e2%80%9cwhy-not%e2%80%9d-drug/</guid>
		<description><![CDATA[Naltrexone is a blocker of opioid receptors and is used in patients who have overdosed on narcotics, but at low doses, there is lab-based work, largely conducted by a single group, that suggests that low dose naltrexone can have immunostimulatory properties and even directly kill cancer cells by a process called apoptosis, a self-destruct program [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/04/04/ldn-miracle-or-no/feed/</wfw:commentRss>
		<slash:comments>8</slash:comments>
		</item>
		<item>
		<title>EGFR Molecular Markers and the Impact of Gene Mutations</title>
		<link>http://cancergrace.org/cancer-treatments/2009/03/04/egfr-molecular-markers/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/03/04/egfr-molecular-markers/#comments</comments>
		<pubDate>Thu, 05 Mar 2009 07:35:50 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Core Concepts]]></category>
		<category><![CDATA[EGFR mutations and other molecular markers]]></category>
		<category><![CDATA[Epidermal growth factor receptor (EGFR)-based therapies]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Molecular Markers]]></category>
		<category><![CDATA[Non-Small Cell Lung Cancer (NSCLC)]]></category>
		<category><![CDATA[Second-line treatment]]></category>
		<category><![CDATA[Targeted therapies]]></category>
		<category><![CDATA[Targeted Therapies, Activity and Side Effects]]></category>
		<category><![CDATA[Third-line therapy and beyond]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Cancer Treatment]]></category>
		<category><![CDATA[EGFR]]></category>
		<category><![CDATA[EGFR Based Therapy]]></category>
		<category><![CDATA[Gene Mutations]]></category>
		<category><![CDATA[NSCLC]]></category>
		<category><![CDATA[Side Effects]]></category>
		<category><![CDATA[Targeted Theraphy]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/2009/03/04/egfr-molecular-markers/</guid>
		<description><![CDATA[We&#8217;ve been talking about the potentially relevant molecular markers for EGFR, and the importance of EGFR as a cancer target (see prior post), without really describing what these markers are. There are three main aspects of EGFR biology that have been studied for their potential predictive value in consideration of EGFR inhibitor therapy, whether the [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/03/04/egfr-molecular-markers/feed/</wfw:commentRss>
		<slash:comments>3</slash:comments>
		</item>
		<item>
		<title>What is EGFR and Why Do We Target It?</title>
		<link>http://cancergrace.org/cancer-treatments/2009/03/02/egfr-basics/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/03/02/egfr-basics/#comments</comments>
		<pubDate>Tue, 03 Mar 2009 05:41:30 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Epidermal growth factor receptor (EGFR)-based therapies]]></category>
		<category><![CDATA[Molecular Markers]]></category>
		<category><![CDATA[Targeted therapies]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[apoptosis]]></category>
		<category><![CDATA[cell signaling]]></category>
		<category><![CDATA[EGFR]]></category>
		<category><![CDATA[EGFR Based Therapy]]></category>
		<category><![CDATA[EGFR mutation]]></category>
		<category><![CDATA[EGFR TKI]]></category>
		<category><![CDATA[epidermal growth factor receptor]]></category>
		<category><![CDATA[HER family]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[TKI]]></category>
		<category><![CDATA[tyrosine kinase inhibitor]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/2009/03/02/egfr-basics/</guid>
		<description><![CDATA[The topic of what is EGFR is one that really deserves to have been covered here from the beginning, but somehow I skipped to the drugs and what they do in cancer patients. It&#8217;s time to take a step back and discuss EGFR and why it&#8217;s been an important target in cancer. EGFR stands for [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/03/02/egfr-basics/feed/</wfw:commentRss>
		<slash:comments>4</slash:comments>
		</item>
		<item>
		<title>Loss of Appetite and Weight Loss: A Very Common and Difficult Problem for Cancer Patients</title>
		<link>http://cancergrace.org/cancer-treatments/2009/02/16/acs-mgmt/</link>
		<comments>http://cancergrace.org/cancer-treatments/2009/02/16/acs-mgmt/#comments</comments>
		<pubDate>Tue, 17 Feb 2009 02:44:51 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Supportive care]]></category>
		<category><![CDATA[Cancer Treatment]]></category>
		<category><![CDATA[Loss of Appetite]]></category>
		<category><![CDATA[Weight Loss]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/2009/02/16/acs-mgmt/</guid>
		<description><![CDATA[Loss of appetite and the weight loss that accompanies it are very common problems, seen in up to 80% of patients with advanced cancers, and this issue certainly appears as an issue on the discussion boards. In many cases, it’s one issue on a list of problems, and indeed we’ve gone far too long without [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2009/02/16/acs-mgmt/feed/</wfw:commentRss>
		<slash:comments>7</slash:comments>
		</item>
		<item>
		<title>Inhibiting the mTOR Pathway as an Anti-Cancer Strategy</title>
		<link>http://cancergrace.org/cancer-treatments/2008/12/14/mtor-moa-intro/</link>
		<comments>http://cancergrace.org/cancer-treatments/2008/12/14/mtor-moa-intro/#comments</comments>
		<pubDate>Mon, 15 Dec 2008 02:55:08 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Cancer Tretament]]></category>
		<category><![CDATA[EGFR]]></category>
		<category><![CDATA[mTOR]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/2008/12/14/mtor-moa-intro/</guid>
		<description><![CDATA[There&#8217;s a class of drugs that are being studied in fighting cancer, known as mTOR inhibitors. mTOR stands for mammalian target of rapamycin, which is an immunosuppressant drug that also has anti-fungal activity, but which was also found to have anti-proliferative activity (keeping cells from growing and dividing), which suggesed that it could have useful [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2008/12/14/mtor-moa-intro/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Easing the Strain of Cancer-Related Fatigue and &#8220;Chemo-Brain&#8221;</title>
		<link>http://cancergrace.org/cancer-treatments/2008/12/02/crf-and-chemobrain-rx-and-bsc/</link>
		<comments>http://cancergrace.org/cancer-treatments/2008/12/02/crf-and-chemobrain-rx-and-bsc/#comments</comments>
		<pubDate>Wed, 03 Dec 2008 01:12:02 +0000</pubDate>
		<dc:creator>Dr Zucker</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Supportive care]]></category>
		<category><![CDATA[Cancer Treatment]]></category>
		<category><![CDATA[Cancer-Related Fatigue]]></category>
		<category><![CDATA[Chemo-Brain]]></category>
		<category><![CDATA[CRF]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/2008/12/02/crf-and-chemobrain-rx-and-bsc/</guid>
		<description><![CDATA[In recent years, more people are cured or living with cancer as a chronic illness because cancer treatments have improved. As a result, treatment after effects and the challenges they present are becoming increasingly apparent. Two common after effects are cancer-related fatigue (CRF) and cognitive impairment, also known as “chemo-brain.” The National Comprehensive Cancer Network [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2008/12/02/crf-and-chemobrain-rx-and-bsc/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>New Effective Treatment for Opioid-Induced Constipation</title>
		<link>http://cancergrace.org/cancer-treatments/2008/08/08/methylnatrexone-nejm-study/</link>
		<comments>http://cancergrace.org/cancer-treatments/2008/08/08/methylnatrexone-nejm-study/#comments</comments>
		<pubDate>Fri, 08 Aug 2008 20:13:59 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Supportive care]]></category>
		<category><![CDATA[Cancer Treatment]]></category>
		<category><![CDATA[Opioid-Induced Constipation]]></category>
		<category><![CDATA[Relistor]]></category>

		<guid isPermaLink="false">http://cancergrace.org/cancer-treatments/2008/08/08/methylnatrexone-nejm-study/</guid>
		<description><![CDATA[It&#8217;s not a glamourous topic, but severe constipation due to opioid (narcotic) medications is a major issue in managing pain from cancer. Opioid medications like morphine, oxycodone, dilaudid, and fentanyl are often needed to manage cancer-related pain effectively, but they come with some baggage. Although I strongly encourage my patients who need narcotics to not [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2008/08/08/methylnatrexone-nejm-study/feed/</wfw:commentRss>
		<slash:comments>5</slash:comments>
		</item>
		<item>
		<title>New Treatment Being Developed for EGFR Inhibitor Skin Rash</title>
		<link>http://cancergrace.org/cancer-treatments/2008/04/13/menadione-for-egfr-rash/</link>
		<comments>http://cancergrace.org/cancer-treatments/2008/04/13/menadione-for-egfr-rash/#comments</comments>
		<pubDate>Mon, 14 Apr 2008 05:42:39 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Epidermal growth factor receptor (EGFR)-based therapies]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Rash and other side effects]]></category>
		<category><![CDATA[Cancer Treatment]]></category>
		<category><![CDATA[EGFR]]></category>
		<category><![CDATA[EGFR Based Therapy]]></category>
		<category><![CDATA[Side Effects]]></category>

		<guid isPermaLink="false">http://onctalk.com/2008/04/13/menadione-for-egfr-rash/</guid>
		<description><![CDATA[The leading side effect of EGFR inhibitors, both the oral tyrosine kinase inhibitors (such as tarceva (erlotinib)) and the IV monoclonal antibodies (such as erbitux (cetuximab)), is rash, dryness, and other skin side effects. While a rash sounds modest to many people compared to many of the leading problems with chemo, many of the members [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2008/04/13/menadione-for-egfr-rash/feed/</wfw:commentRss>
		<slash:comments>4</slash:comments>
		</item>
		<item>
		<title>EGFR Inhibitor Combination Tested in Advanced NSCLC</title>
		<link>http://cancergrace.org/cancer-treatments/2008/03/21/egfr-combo-in-adv-nsclc/</link>
		<comments>http://cancergrace.org/cancer-treatments/2008/03/21/egfr-combo-in-adv-nsclc/#comments</comments>
		<pubDate>Sat, 22 Mar 2008 05:09:13 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Epidermal growth factor receptor (EGFR)-based therapies]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Non-Small Cell Lung Cancer (NSCLC)]]></category>
		<category><![CDATA[Second-line treatment]]></category>
		<category><![CDATA[Stage IV/Advanced/Metastatic NSCLC]]></category>
		<category><![CDATA[Targeted therapies]]></category>
		<category><![CDATA[Third-line therapy and beyond]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Current Clinical Trials]]></category>
		<category><![CDATA[EGFR]]></category>
		<category><![CDATA[EGFR Based Therapy]]></category>
		<category><![CDATA[NSCLC]]></category>
		<category><![CDATA[Targeted Therapy]]></category>

		<guid isPermaLink="false">http://onctalk.com/2008/03/21/egfr-combo-in-adv-nsclc/</guid>
		<description><![CDATA[As I&#8217;ve described in various posts about targeting the epidermal growth factor receptor (EGFR), one of the main signals that is important in many lung cancers, there are agents like gefitinib (iressa) and erlotinib (tarceva) that target the internal switch that triggers activity inside the cell, and there are agents like cetuximab (erbitux) that work [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2008/03/21/egfr-combo-in-adv-nsclc/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>Targeting Insulin-Like Growth Factor 1-Receptor (IGF-1R) in Cancer</title>
		<link>http://cancergrace.org/cancer-treatments/2008/03/09/igf-1r-in-cancer/</link>
		<comments>http://cancergrace.org/cancer-treatments/2008/03/09/igf-1r-in-cancer/#comments</comments>
		<pubDate>Mon, 10 Mar 2008 06:06:42 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Cancer Treatments]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Other targeted therapies]]></category>
		<category><![CDATA[Pathology/Lung Cancer Subtypes]]></category>
		<category><![CDATA[Targeted therapies]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Cancer Treatment]]></category>
		<category><![CDATA[IGF-1R]]></category>
		<category><![CDATA[Targeted Therapy]]></category>

		<guid isPermaLink="false">http://onctalk.com/2008/03/09/igf-1r-in-cancer/</guid>
		<description><![CDATA[In addition to several molecular targets that have been well studied for several years, such as the epidermal growth factor receptor (EGFR) and vascular endothelial growth factor (VEGF), new targets are emerging as potentially fruitful approaches to combating cancer. One of these is the insulin-like growth factor receptor, or IGF-1R. IGF-1R is involved in the [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2008/03/09/igf-1r-in-cancer/feed/</wfw:commentRss>
		<slash:comments>1</slash:comments>
		</item>
		<item>
		<title>Recent Results with Talactoferrin: Reason to Move Forward</title>
		<link>http://cancergrace.org/cancer-treatments/2008/01/27/tlf-single-agent-post-ii/</link>
		<comments>http://cancergrace.org/cancer-treatments/2008/01/27/tlf-single-agent-post-ii/#comments</comments>
		<pubDate>Mon, 28 Jan 2008 01:01:35 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Current Clinical Trials]]></category>
		<category><![CDATA[Immune/Vaccine-based therapies]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Non-Small Cell Lung Cancer (NSCLC)]]></category>
		<category><![CDATA[Second-line treatment]]></category>
		<category><![CDATA[Third-line therapy and beyond]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Talactoferrin]]></category>
		<category><![CDATA[TLF]]></category>
		<category><![CDATA[Vaccine Based Therapy]]></category>

		<guid isPermaLink="false">http://onctalk.com/2008/01/27/tlf-single-agent-post-ii/</guid>
		<description><![CDATA[As I described in part I of this subject (last post here), lactoferrin is an immunostimulatory protein that is found in highest concentrations in breast milk (hence the name), and the recombinant form talactoferrin alfa (TLF) was combined with chemo in a randomized phase II study of front line advanced NSCLC in which the combination [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2008/01/27/tlf-single-agent-post-ii/feed/</wfw:commentRss>
		<slash:comments>15</slash:comments>
		</item>
		<item>
		<title>Talactoferrin Alfa (TLF): Mother&#8217;s Milk Becomes Cancer Treatment</title>
		<link>http://cancergrace.org/cancer-treatments/2008/01/26/tlf-for-nsclc/</link>
		<comments>http://cancergrace.org/cancer-treatments/2008/01/26/tlf-for-nsclc/#comments</comments>
		<pubDate>Sun, 27 Jan 2008 01:29:55 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[First-line treatment]]></category>
		<category><![CDATA[Immune/Vaccine-based therapies]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Non-Small Cell Lung Cancer (NSCLC)]]></category>
		<category><![CDATA[Stage IV/Advanced/Metastatic NSCLC]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Current Clinical Trials]]></category>
		<category><![CDATA[Talactoferrin]]></category>
		<category><![CDATA[TLF]]></category>
		<category><![CDATA[Vaccine Based Therapy]]></category>

		<guid isPermaLink="false">http://onctalk.com/2008/01/26/tlf-for-nsclc/</guid>
		<description><![CDATA[We&#8217;ve covered several novel agents for treating lung cancer, but a new one that has shown promise in early studies and now is the subject of larger phase III trials is a drug called talactoferrin alfa (TLF), from a small company based in Houston called Agennix. I think it&#8217;s possible that much of the reason [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2008/01/26/tlf-for-nsclc/feed/</wfw:commentRss>
		<slash:comments>1</slash:comments>
		</item>
		<item>
		<title>Heat Shock Protein Inhibition as an Anti-Cancer Treatment</title>
		<link>http://cancergrace.org/cancer-treatments/2007/12/26/hsp-and-ca/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/12/26/hsp-and-ca/#comments</comments>
		<pubDate>Thu, 27 Dec 2007 05:41:30 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Current Clinical Trials]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Other targeted therapies]]></category>
		<category><![CDATA[Targeted therapies]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Cancer Treatment]]></category>
		<category><![CDATA[Heat Shock Protein Inhibition]]></category>
		<category><![CDATA[Targeted Therapy]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/12/26/hsp-and-ca/</guid>
		<description><![CDATA[There&#8217;s a new class of anti-cancer drugs that are being studied, including in lung cancer, known as heat shock proteins, or HSPs. These are sometimes referred to as &#8220;stress proteins&#8221; because they can be induced to be generated in higher concentrations in response to stresses like heat, cold, low oxygen levels, etc. But HSPs are [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/12/26/hsp-and-ca/feed/</wfw:commentRss>
		<slash:comments>8</slash:comments>
		</item>
		<item>
		<title>Vinflunine (Javlor) as Second Line NSCLC Option?</title>
		<link>http://cancergrace.org/cancer-treatments/2007/12/20/vinflunine-2nd-line-nsclc/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/12/20/vinflunine-2nd-line-nsclc/#comments</comments>
		<pubDate>Fri, 21 Dec 2007 06:44:43 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Chemotherapy]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Non-Small Cell Lung Cancer (NSCLC)]]></category>
		<category><![CDATA[Second-line treatment]]></category>
		<category><![CDATA[Stage IV/Advanced/Metastatic NSCLC]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Cheotherapy]]></category>
		<category><![CDATA[Javlor]]></category>
		<category><![CDATA[NSCLC]]></category>
		<category><![CDATA[Vinflunine]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/12/20/vinflunine-2nd-line-nsclc/</guid>
		<description><![CDATA[Although much of our focus has been on targeted therapies, there are still new conventional chemotherapies that are being introduced and may have a meaningful impact on lung cancer. One that has been tested in late clinical trials, including a phase III randomized study, is vinflunine, which is a novel version of a chemo drug [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/12/20/vinflunine-2nd-line-nsclc/feed/</wfw:commentRss>
		<slash:comments>3</slash:comments>
		</item>
		<item>
		<title>Thalidomide in Lung Cancer: Answers from Korea</title>
		<link>http://cancergrace.org/cancer-treatments/2007/09/21/thalidomide-in-lung-cancer/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/09/21/thalidomide-in-lung-cancer/#comments</comments>
		<pubDate>Sat, 22 Sep 2007 04:41:06 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Anti-angiogenic agents]]></category>
		<category><![CDATA[Extensive Disease Small Cell Lung Cancer (ED-SCLC)]]></category>
		<category><![CDATA[First-line treatment]]></category>
		<category><![CDATA[Limited Disease Small Cell Lung Cancer (LD-SCLC)]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Non-Small Cell Lung Cancer (NSCLC)]]></category>
		<category><![CDATA[Other targeted therapies]]></category>
		<category><![CDATA[Small Cell Lung Cancer (SCLC)]]></category>
		<category><![CDATA[Stage IV/Advanced/Metastatic NSCLC]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[ED-SCLC]]></category>
		<category><![CDATA[LD-SCLC]]></category>
		<category><![CDATA[NSCLC]]></category>
		<category><![CDATA[SCLC]]></category>
		<category><![CDATA[Thalidomide]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/09/21/thalidomide-in-lung-cancer/</guid>
		<description><![CDATA[To many outside of oncology, thalidomide is primarily known for causing severe birth defects in women who received it in the 1960s as a sedative and treatment for morning sickness. These birth defects, in which babies were born with no arms or legs but with hands and feet directly attached to their trunks, was likely [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/09/21/thalidomide-in-lung-cancer/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Novel Agents for Lung Cancer: Proteasome Inhibition with Velcade (Bortezomib)</title>
		<link>http://cancergrace.org/cancer-treatments/2007/08/31/proteasome-inhibitionvelcade-in-lung-cancer/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/08/31/proteasome-inhibitionvelcade-in-lung-cancer/#comments</comments>
		<pubDate>Sat, 01 Sep 2007 02:47:03 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Bronchioloalveolar Carcinoma (BAC)]]></category>
		<category><![CDATA[Extensive Disease Small Cell Lung Cancer (ED-SCLC)]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Non-Small Cell Lung Cancer (NSCLC)]]></category>
		<category><![CDATA[Other targeted therapies]]></category>
		<category><![CDATA[Second-line treatment]]></category>
		<category><![CDATA[Small Cell Lung Cancer (SCLC)]]></category>
		<category><![CDATA[Special Populations in Lung Cancer]]></category>
		<category><![CDATA[Stage IV/Advanced/Metastatic NSCLC]]></category>
		<category><![CDATA[Targeted therapies]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Bortezomib]]></category>
		<category><![CDATA[ED-SCLC]]></category>
		<category><![CDATA[NSCLC]]></category>
		<category><![CDATA[Proteasome Inhibition]]></category>
		<category><![CDATA[SCLC]]></category>
		<category><![CDATA[Targeted Therapy]]></category>
		<category><![CDATA[Velcade]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/08/31/proteasome-inhibitionvelcade-in-lung-cancer/</guid>
		<description><![CDATA[Much of the focus on novel agents has been on strategies like inhibition of the epidermal growth factor receptor (EGFR) that can stimulate tumor growth, or anti-angiogenesis, blocking the tumor blood supply. But there are other, novel therapies that are also being tested in lung cancer as well. One of these is proteosome inhibition, with [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/08/31/proteasome-inhibitionvelcade-in-lung-cancer/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Vascular Disrupting Agent AS1404/ ASA404/ DMXAA: A Variant on Anti-Angiogenesis</title>
		<link>http://cancergrace.org/cancer-treatments/2007/08/23/vasc-disrupting-agents-asa404/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/08/23/vasc-disrupting-agents-asa404/#comments</comments>
		<pubDate>Thu, 23 Aug 2007 23:44:43 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Anti-angiogenic agents]]></category>
		<category><![CDATA[Current Clinical Trials]]></category>
		<category><![CDATA[First-line treatment]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Non-Small Cell Lung Cancer (NSCLC)]]></category>
		<category><![CDATA[Other targeted therapies]]></category>
		<category><![CDATA[Stage IV/Advanced/Metastatic NSCLC]]></category>
		<category><![CDATA[Metastatic NSCLC]]></category>
		<category><![CDATA[NSCLC]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/08/23/vasc-disrupting-agents-asa404/</guid>
		<description><![CDATA[First, I want to thank members Jim (dadawg001) and Neil (neilb) for bringing up this topic in the Discussion/Q&#038;A Forum yesterday. Amazingly, yesterday morning I happened to be reviewing slides in my collection on a novel agent and approach that I thought would make a good topic for a post here: the drug DMXAA, which [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/08/23/vasc-disrupting-agents-asa404/feed/</wfw:commentRss>
		<slash:comments>7</slash:comments>
		</item>
		<item>
		<title>DCA Revisited: Is It A Breakthrough Yet?</title>
		<link>http://cancergrace.org/cancer-treatments/2007/07/19/dca-update/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/07/19/dca-update/#comments</comments>
		<pubDate>Fri, 20 Jul 2007 03:27:46 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Current Clinical Trials]]></category>
		<category><![CDATA[General]]></category>
		<category><![CDATA[General Lung Cancer Issues]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Other targeted therapies]]></category>
		<category><![CDATA[DCA]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/07/19/dca-update/</guid>
		<description><![CDATA[I&#8217;m surprised to find that I&#8217;m moving to a topic that may actually be more controversial than a Michael Moore movie, but in fact, I think that&#8217;s where I&#8217;m headed. Several months ago, I wrote a post about dichloroacetate, or DCA, which is a chemical used to treat a childhood disease called congenital lactic acidosis, [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/07/19/dca-update/feed/</wfw:commentRss>
		<slash:comments>24</slash:comments>
		</item>
		<item>
		<title>Vorinostat/SAHA: Another Targeted Therapy Being Tested in Lung Cancer</title>
		<link>http://cancergrace.org/cancer-treatments/2007/07/16/vorinostatsaha-in-lung-cancer/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/07/16/vorinostatsaha-in-lung-cancer/#comments</comments>
		<pubDate>Mon, 16 Jul 2007 23:44:32 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Current Clinical Trials]]></category>
		<category><![CDATA[First-line treatment]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Non-Small Cell Lung Cancer (NSCLC)]]></category>
		<category><![CDATA[Other targeted therapies]]></category>
		<category><![CDATA[Stage IV/Advanced/Metastatic NSCLC]]></category>
		<category><![CDATA[Targeted therapies]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Metastatic NSCLC]]></category>
		<category><![CDATA[NSCLC]]></category>
		<category><![CDATA[SAHA]]></category>
		<category><![CDATA[Targeted Therapy]]></category>
		<category><![CDATA[Vorinostat]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/07/16/vorinostatsaha-in-lung-cancer/</guid>
		<description><![CDATA[I&#8217;ve got a lot of things on my list of things to cover in the near future&#8230;patient sex differences in lung cancer and estrogen, an update I&#8217;m trying to generate on DCA (dichloroacetate), the concept of pharmacodynamic separation of chemo and EGFR inhibitors, more on the trials from ASCO that may be changing our practice [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/07/16/vorinostatsaha-in-lung-cancer/feed/</wfw:commentRss>
		<slash:comments>11</slash:comments>
		</item>
		<item>
		<title>Axitinib: New Drug with Activity in Lung Cancer</title>
		<link>http://cancergrace.org/cancer-treatments/2007/07/01/axitinib-in-lung-cancer/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/07/01/axitinib-in-lung-cancer/#comments</comments>
		<pubDate>Sun, 01 Jul 2007 20:27:54 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Anti-angiogenic agents]]></category>
		<category><![CDATA[Current Clinical Trials]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Multikinase inhibitors]]></category>
		<category><![CDATA[Targeted therapies]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Axitinib]]></category>
		<category><![CDATA[Targeted Therapy]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/07/01/axitinib-in-lung-cancer/</guid>
		<description><![CDATA[A few new agents emerged from the ASCO 2007 meeting as very real potential players in lung cancer. Probably at the lead of that list, in my opinion, was axitinib (AG-013736, now a Pfizer product). Similar to agents like sunitinib and sorafenib, this is an oral agent that blocks a target called the Platelet-Derived Growth [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/07/01/axitinib-in-lung-cancer/feed/</wfw:commentRss>
		<slash:comments>8</slash:comments>
		</item>
		<item>
		<title>Selecting Chemo by Extreme Drug Resistance</title>
		<link>http://cancergrace.org/cancer-treatments/2007/06/23/edr-assay-for-selecting-chemo/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/06/23/edr-assay-for-selecting-chemo/#comments</comments>
		<pubDate>Sun, 24 Jun 2007 05:58:49 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Chemotherapy]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Pathology/Lung Cancer Subtypes]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Cancer Treatment]]></category>
		<category><![CDATA[Drug Resistance]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/06/23/edr-assay-for-selecting-chemo/</guid>
		<description><![CDATA[My recent post about selecting the right treatment for an individual tumor is part of a long history of trying to tailor cancer therapy. Many companies offer such services, and in fact advertise them heavily. However, the oncology community as a whole has not enthusiastically embraced such approaches, as many patients suggesting these tests may [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/06/23/edr-assay-for-selecting-chemo/feed/</wfw:commentRss>
		<slash:comments>1</slash:comments>
		</item>
		<item>
		<title>Temozolomide (Temodar) for Brain Metastases</title>
		<link>http://cancergrace.org/cancer-treatments/2007/04/30/temodar-for-brain-mets/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/04/30/temodar-for-brain-mets/#comments</comments>
		<pubDate>Tue, 01 May 2007 04:21:55 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Chemotherapy]]></category>
		<category><![CDATA[Extensive Disease Small Cell Lung Cancer (ED-SCLC)]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Management of Brain Metastases]]></category>
		<category><![CDATA[Non-Small Cell Lung Cancer (NSCLC)]]></category>
		<category><![CDATA[Radiation therapy]]></category>
		<category><![CDATA[Small Cell Lung Cancer (SCLC)]]></category>
		<category><![CDATA[Stage IV/Advanced/Metastatic NSCLC]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Brain Metastases]]></category>
		<category><![CDATA[ED-SCLC]]></category>
		<category><![CDATA[Metastatic NSCLC]]></category>
		<category><![CDATA[NSCLC]]></category>
		<category><![CDATA[SCLC]]></category>
		<category><![CDATA[Temozolomide]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/04/30/temodar-for-brain-mets/</guid>
		<description><![CDATA[Historically, chemotherapy has had a relatively minor role in the management of brain metastases. Although there is a rather low response rate in the brain from some standard lung cancer chemo regimens, we generally conclude that most of our chemo can&#8217;t be too effective in the brain because of the blood-brain barrier (BBB) that is [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/04/30/temodar-for-brain-mets/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>COX-2/EGFR Inhibitor Therapy: Hope or Hype?</title>
		<link>http://cancergrace.org/cancer-treatments/2007/04/13/cox-2-and-egfr-inhibitors-for-nsclc/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/04/13/cox-2-and-egfr-inhibitors-for-nsclc/#comments</comments>
		<pubDate>Sat, 14 Apr 2007 00:23:55 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Anti-angiogenic agents]]></category>
		<category><![CDATA[Current Clinical Trials]]></category>
		<category><![CDATA[EGFR mutations and other molecular markers]]></category>
		<category><![CDATA[Epidermal growth factor receptor (EGFR)-based therapies]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Never-smokers with lung cancer]]></category>
		<category><![CDATA[Non-Small Cell Lung Cancer (NSCLC)]]></category>
		<category><![CDATA[Other targeted therapies]]></category>
		<category><![CDATA[Second-line treatment]]></category>
		<category><![CDATA[Stage IV/Advanced/Metastatic NSCLC]]></category>
		<category><![CDATA[Targeted therapies]]></category>
		<category><![CDATA[Third-line therapy and beyond]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[EGDR Inhibitor Therapy]]></category>
		<category><![CDATA[EGFR Based Therapy]]></category>
		<category><![CDATA[Metastatic NSCLC]]></category>
		<category><![CDATA[NSCLC]]></category>
		<category><![CDATA[Special Populations in Lung Cancer]]></category>
		<category><![CDATA[Targeted Therapy]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/04/13/cox-2-and-egfr-inhibitors-for-nsclc/</guid>
		<description><![CDATA[While there have been studies of the COX-2 inhibitor celebrex in combination with chemo for treating NSCLC, the palpable buzz about celebrex in treating lung cancer has been from a trial by my friend Karen Reckamp, formerly at UCLA, now recently moved to City of Hope Cancer Center in nearby Duarte, CA. Several studies have [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/04/13/cox-2-and-egfr-inhibitors-for-nsclc/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>Xyotax: A New Taxane Targeted for Women Only</title>
		<link>http://cancergrace.org/cancer-treatments/2007/04/01/xyotax-in-nsclc/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/04/01/xyotax-in-nsclc/#comments</comments>
		<pubDate>Mon, 02 Apr 2007 04:52:37 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Chemotherapy]]></category>
		<category><![CDATA[Current Clinical Trials]]></category>
		<category><![CDATA[First-line treatment]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Non-Small Cell Lung Cancer (NSCLC)]]></category>
		<category><![CDATA[Older and/or frail patients with lung cancer]]></category>
		<category><![CDATA[Sex-based differences in lung cancer]]></category>
		<category><![CDATA[Special Populations in Lung Cancer]]></category>
		<category><![CDATA[Stage IV/Advanced/Metastatic NSCLC]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Metastatic NSCLC]]></category>
		<category><![CDATA[NSCLC]]></category>
		<category><![CDATA[Taxane]]></category>
		<category><![CDATA[Xyotax]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/04/01/xyotax-in-nsclc/</guid>
		<description><![CDATA[Similar in concept to Abraxane, paclitaxel poliglumex (PPX, or Xyotax) is another novel formulation of paclitaxel in which the taxane is bound to a biodegradeable polymer utilizing a polyglutamate drug delivery system. As with Abraxane, this allows administration without solvents over a recommended infusion time of 10-20 minutes and potentially allowing for improved delivery of [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/04/01/xyotax-in-nsclc/feed/</wfw:commentRss>
		<slash:comments>8</slash:comments>
		</item>
		<item>
		<title>Nanoparticle Albumin Bound Paclitaxel for Lung Cancer: New, But is it Improved?</title>
		<link>http://cancergrace.org/cancer-treatments/2007/03/30/abraxane-in-nsclc/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/03/30/abraxane-in-nsclc/#comments</comments>
		<pubDate>Sat, 31 Mar 2007 05:52:04 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Chemotherapy]]></category>
		<category><![CDATA[Current Clinical Trials]]></category>
		<category><![CDATA[First-line treatment]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Non-Small Cell Lung Cancer (NSCLC)]]></category>
		<category><![CDATA[Stage IV/Advanced/Metastatic NSCLC]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Metastatic NSCLC]]></category>
		<category><![CDATA[NSCLC]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/03/30/abraxane-in-nsclc/</guid>
		<description><![CDATA[Paclitaxel, marketed name Taxol, is among the most commonly used drugs in oncology in general, and definitely also for lung cancer, particularly NSCLC. The combination of carboplatin/taxol is the most frequently prescribed combination for advanced NSCLC in the US and is also employed in many other settings for NSCLC as well. However, there are several [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/03/30/abraxane-in-nsclc/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>Aurora Kinase Inhibitors as a Novel Anti-Cancer Approach</title>
		<link>http://cancergrace.org/cancer-treatments/2007/03/08/aurora-kinase-inhibitors/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/03/08/aurora-kinase-inhibitors/#comments</comments>
		<pubDate>Fri, 09 Mar 2007 06:09:26 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Current Clinical Trials]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Other targeted therapies]]></category>
		<category><![CDATA[Targeted therapies]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Aurora Kinase Inhibitors]]></category>
		<category><![CDATA[Targeted Therapy]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/03/08/aurora-kinase-inhibitors/</guid>
		<description><![CDATA[One emerging class of targeted therapy for cancer that is just entering clinical trials is a group of agents called aurora kinases. A kinase is a protein that modifies the structure and function of other proteins by adding a phosphate group to it, which is like flipping an on/off switch. Aurora was discovered by Dr. [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/03/08/aurora-kinase-inhibitors/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>Gene Expression and Refining &#8220;How to Treat&#8221;</title>
		<link>http://cancergrace.org/cancer-treatments/2007/02/25/gene-expression-the-right-drugs-for-the-right-patient/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/02/25/gene-expression-the-right-drugs-for-the-right-patient/#comments</comments>
		<pubDate>Mon, 26 Feb 2007 03:00:31 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Chemotherapy]]></category>
		<category><![CDATA[Gene Profiles/Molecular Signatures]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Targeted therapies]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Gene Expression]]></category>
		<category><![CDATA[Gene Profiles]]></category>
		<category><![CDATA[Molecular Signatures]]></category>
		<category><![CDATA[Targeted Therapy]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/02/25/gene-expression-the-right-drugs-for-the-right-patient/</guid>
		<description><![CDATA[In the Keynote Lecture at the Targeted Therapies in the Treatment of Lung Cancer Conference, Dr. Joseph Nevins from Duke&#8217;s described emerging approaches for how to personalize cancer management, including who to treat, and how to treat. I described in my last posts his efforts to refine our understanding of which patients with early stage, [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/02/25/gene-expression-the-right-drugs-for-the-right-patient/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>Bisphosphonates for Skeletal Metastases in Lung Cancer</title>
		<link>http://cancergrace.org/cancer-treatments/2007/02/23/bisphosphonates-for-lung-cancer/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/02/23/bisphosphonates-for-lung-cancer/#comments</comments>
		<pubDate>Fri, 23 Feb 2007 07:22:29 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[General Lung Cancer Issues]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Management of Bone Metastases]]></category>
		<category><![CDATA[Biophosphonates]]></category>
		<category><![CDATA[Bone Metastases]]></category>
		<category><![CDATA[Skeletal Metastases]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/02/23/bisphosphonates-for-lung-cancer/</guid>
		<description><![CDATA[In addition to local treatments such as surgery or radiation for more immediate and directed therapy for bone metastases, there is a commonly used and FDA-approved approach with Zometa, also known as zoledronate or zoledronic acid. It is one of a class of drugs known as bisphosphonates that can reduce the rate of progression with [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/02/23/bisphosphonates-for-lung-cancer/feed/</wfw:commentRss>
		<slash:comments>5</slash:comments>
		</item>
		<item>
		<title>Targeted Therapies in Lung Cancer Conference</title>
		<link>http://cancergrace.org/cancer-treatments/2007/02/21/targeted-therapies-in-lung-cancer-conference/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/02/21/targeted-therapies-in-lung-cancer-conference/#comments</comments>
		<pubDate>Wed, 21 Feb 2007 17:04:51 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Targeted Therapy]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/02/21/targeted-therapies-in-lung-cancer-conference/</guid>
		<description><![CDATA[I&#8217;ve been covering bone metastases for the past several posts, because it&#8217;s an important topic that affects lots of people with cancer, and because there are many approaches that can potentially be involved. I&#8217;ll finish my coverage of that topic with one more post. In the meantime, I&#8217;m in LA now to speak at and [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/02/21/targeted-therapies-in-lung-cancer-conference/feed/</wfw:commentRss>
		<slash:comments>3</slash:comments>
		</item>
		<item>
		<title>DCA and the Journey from In Vitro Studies to Cancer Treatment</title>
		<link>http://cancergrace.org/cancer-treatments/2007/02/04/dca-and-drug-development-challenges/</link>
		<comments>http://cancergrace.org/cancer-treatments/2007/02/04/dca-and-drug-development-challenges/#comments</comments>
		<pubDate>Mon, 05 Feb 2007 01:47:21 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Current Clinical Trials]]></category>
		<category><![CDATA[General]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Other targeted therapies]]></category>
		<category><![CDATA[Targeted therapies]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Cancer Treatment]]></category>
		<category><![CDATA[DCA]]></category>
		<category><![CDATA[In Vitro Studies]]></category>

		<guid isPermaLink="false">http://onctalk.com/2007/02/04/dca-and-drug-development-challenges/</guid>
		<description><![CDATA[I received a question on the discussion forum, in the setting of a lot of internet discussion, about an an agent called dichloroacetate, or DCA, as a potential anticancer therapy. This excitement is based on a study out of the University of Alberta in Canada, that appeared in the journal Cancer Cell (article here). This [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2007/02/04/dca-and-drug-development-challenges/feed/</wfw:commentRss>
		<slash:comments>4</slash:comments>
		</item>
		<item>
		<title>Sunitinib/Sutent in NSCLC</title>
		<link>http://cancergrace.org/cancer-treatments/2006/12/24/sutent-in-advanced-nsclc/</link>
		<comments>http://cancergrace.org/cancer-treatments/2006/12/24/sutent-in-advanced-nsclc/#comments</comments>
		<pubDate>Sun, 24 Dec 2006 19:58:05 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Bronchioloalveolar Carcinoma (BAC)]]></category>
		<category><![CDATA[Current Clinical Trials]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Multikinase inhibitors]]></category>
		<category><![CDATA[Never-smokers with lung cancer]]></category>
		<category><![CDATA[Non-Small Cell Lung Cancer (NSCLC)]]></category>
		<category><![CDATA[Second-line treatment]]></category>
		<category><![CDATA[Special Populations in Lung Cancer]]></category>
		<category><![CDATA[Stage IV/Advanced/Metastatic NSCLC]]></category>
		<category><![CDATA[Targeted therapies]]></category>
		<category><![CDATA[Third-line therapy and beyond]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Metastatic NSCLC]]></category>
		<category><![CDATA[NSCLC]]></category>
		<category><![CDATA[Sunitinib]]></category>
		<category><![CDATA[Targeted Therapy]]></category>

		<guid isPermaLink="false">http://onctalk.com/2006/12/24/sutent-in-advanced-nsclc/</guid>
		<description><![CDATA[Sunitinib (SU11248), with the marketing name Sutent, is another multikinase inhibitor, an oral agent that blocks several potentially important anticancer targets in the cell with one drug. This drug is FDA-approved in treating advanced kidney cancer and also a cancer called GastroIntestinal Stromal Tumor (GIST) after progression or intolerance of Gleevec (imatinib). It inhibits the [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2006/12/24/sutent-in-advanced-nsclc/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>Sorafenib/Nexavar in Non-Small Cell Lung Cancer</title>
		<link>http://cancergrace.org/cancer-treatments/2006/11/30/sorafenibnexavar-in-non-small-cell-lung-cancer/</link>
		<comments>http://cancergrace.org/cancer-treatments/2006/11/30/sorafenibnexavar-in-non-small-cell-lung-cancer/#comments</comments>
		<pubDate>Fri, 01 Dec 2006 01:40:16 +0000</pubDate>
		<dc:creator>Dr West</dc:creator>
				<category><![CDATA[Bronchioloalveolar Carcinoma (BAC)]]></category>
		<category><![CDATA[Current Clinical Trials]]></category>
		<category><![CDATA[First-line treatment]]></category>
		<category><![CDATA[Lung Cancer]]></category>
		<category><![CDATA[Multikinase inhibitors]]></category>
		<category><![CDATA[Never-smokers with lung cancer]]></category>
		<category><![CDATA[Non-Small Cell Lung Cancer (NSCLC)]]></category>
		<category><![CDATA[Other targeted therapies]]></category>
		<category><![CDATA[Second-line treatment]]></category>
		<category><![CDATA[Special Populations in Lung Cancer]]></category>
		<category><![CDATA[Stage IV/Advanced/Metastatic NSCLC]]></category>
		<category><![CDATA[Targeted therapies]]></category>
		<category><![CDATA[Third-line therapy and beyond]]></category>
		<category><![CDATA[Treatment]]></category>
		<category><![CDATA[Nexavar]]></category>
		<category><![CDATA[NSCLC]]></category>
		<category><![CDATA[Sorafenib]]></category>

		<guid isPermaLink="false">http://onctalk.com/2006/11/30/sorafenibnexavar-in-non-small-cell-lung-cancer/</guid>
		<description><![CDATA[Sorafenib, or Nexavar, is an oral &#8220;multi-kinase inhibitor&#8221;. Kinases are specialized proteins that coordinate communitcation networks inside the cell and can modulate cancer cell growth as well as angiogenesis, the tumor blood supply. While many of the molecularly targeted agents I have discussed previously have demonstrated activity in lung cancer and sometimes other tumors, I [...]]]></description>
		<wfw:commentRss>http://cancergrace.org/cancer-treatments/2006/11/30/sorafenibnexavar-in-non-small-cell-lung-cancer/feed/</wfw:commentRss>
		<slash:comments>16</slash:comments>
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