Lung Cancer / Mesothelioma
This work is still early, but it’s been interesting to see a lab-based correlate emerge along with with the observation of women, and particularly older women, doing better in lung cancer studies (several prior posts here). Last year, the folks at Cell Therapeutics, Inc., analyzed results from their trials with Xyotax (post here), which […]
0 Comments I’ve been working with the Lung Cancer Support Community for most of the last year. From the beginning, Katie Brown, who heads that site and a lot of lung cancer advocacy work, has been a great partner as I developed OncTalk, and she’s a tireless champion for the lung cancer community.
I’m planning to do a live […]
Over the past few years, sex-based differences in lung cancer have become increasingly recognized as relevant in prognosis overall and potentially in predicting response to treatment, such as EGFR inhibitors and other targeted therapies. At ASCO 2007, a group led by Dr. Kathy Albain, long committed to learning more about sex differences in lung […]
5 CommentsWe’ve discussed various ways of predicting outcomes with EGFR inhibitors like Tarceva or Iressa using clinical variables like smoking status or BAC subtype, as well as molecular markers like EGFR mutations, or EGFR gene amplification or protein expression. These can all be of value, but we know that the clinical markers are quite inexact, […]
7 CommentsAs a follow-up to my last post and an end to this extended discusison of locally advanced NSCLC before moving to other topics, I’ll just cover some more recent work on the topic of chemo followed by chemo and radiation for stage III NSCLC. In that post, I showed that over the past several […]
0 CommentsThe last topic in our discussion of the evolving field of optimal treatment for locally advanced NSCLC is the potential role for induction chemotherapy before radiation, or, more commonly concurrent chemo/radiation (CT/RT). In my recent post, we covered the new findings from ASCO 2007 that our common practice of giving concurrent CT/RT followed by consolidation chemo, most commonly with taxotere, […]
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