Interview with Lung Cancer Pathologist Matthew Horton, Pt 1: Intro to NSCLC Subtypes


I had the opportunity to sit down with Dr. Matthew Horton, a pathologist who works with my own group at Swedish Cancer Institute in Seattle, at a pathology company called CellNetix.  He did subspecialty training in lung pathology and is a terrific resource for my colleagues and me, and now for a wider audience.

The first part of our discussion focused on the major subtypes (called histologies) of NSCLC, including adenocarcinomas, squamous cell carcinomas, large cell carcinomas, and the related large cell neuroendocrine carcinomas, along with a significant fraction of NSCLC tumors that can’t be classified despite our efforts.  So check out the links below for the audio and video versions of our discussion (the video with a few images of what we’re talking about), and the associated transcript and figures.

dr-horton-intro-to-lc-path-nsclc-subtypes-audio-podcast

dr-horton-intro-to-lc-path-nsclc-subtypes-transcript

dr-horton-intro-to-lc-path-nsclc-subtypes-figures

In subsequent parts of this discussion, we’ll cover the neuroendocrine family that ranges from carcinoids to small cell lung cancer and large cell neuroendocrine carcinomas, the different subtypes of adenocarcinomas, and other aspects of lung cancer pathology.

Related posts:

    Challenging Cases in Lung Cancer Podcast Series: Adjuvant Chemo for a Small NSCLC Tumor with a Satellite Lesion This is the first of a series of podcasts we’ve done, developed in partnershi...

    Dr. Lecia Sequist on the Value of Repeat Biopsies with Ongoing Treatment of Lung Cancer Here’s a continuation of the webinar content by Dr. Lecia Sequist, who i...

    Challenging Cases in Lung Cancer: Acquired Resistance to an EGFR Inhibitor in a Patient with Advanced NSCLC and EGFR Mutation It’s been a while since we released another podcast from the recording I di...

    ASCO Highlights in Lung Cancer Q&A Session ALERT: The links for the podcasts are now fixed. Here’s the question and answe...

    Podcast on Tobacco, Smoking Patterns, and the Association with Lung Cancer Several weeks ago we did a webinar, co-sponsored with LUNGevity Foundation, wit...

Posted in: Lung Cancer, Pathology/Lung Cancer Subtypes

3 Comments  

Rita
Posted on January 25, 2010 at 8:59 pm

Thank you for this! When my husband was diagnosed with “adenocarcinoma of the lung with BAC features,” also stated as “adenocarcinoma of the lung compatible with BAC,” my husband and I were terribly confused. Initially, we were under the impression that BAC was a cancer separate from adenocarcinoma, and when we were then told he had “both,” or a “mixed type,” we got terribly confused. This presentation has clarified a lot of this for us.


LovesLife
Posted on January 26, 2010 at 7:08 am

Very interesting read! Thanks Dr. Horton - looking forward to the rest of the series.

Linda


Catharine
Posted on February 1, 2010 at 3:51 pm

Dr. Horton and Dr. West:

Thank you for an interesting presentation.