GRACE :: Lung Cancer

Interview with Lung Cancer Pathologist Matthew Horton, Pt 1: Intro to NSCLC Subtypes

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I had the opportunity to sit down with Dr. Matthew Horton, a pathologist who works with my own group at Swedish Cancer Institute in Seattle, at a pathology company called CellNetix. He did subspecialty training in lung pathology and is a terrific resource for my colleagues and me, and now for a wider audience.

The first part of our discussion focused on the major subtypes (called histologies) of NSCLC, including adenocarcinomas, squamous cell carcinomas, large cell carcinomas, and the related large cell neuroendocrine carcinomas, along with a significant fraction of NSCLC tumors that can’t be classified despite our efforts. So check out the links below for the audio and video versions of our discussion (the video with a few images of what we’re talking about), and the associated transcript and figures.

dr-horton-intro-to-lc-path-nsclc-subtypes-audio-podcast

dr-horton-intro-to-lc-path-nsclc-subtypes-transcript

dr-horton-intro-to-lc-path-nsclc-subtypes-figures

In subsequent parts of this discussion, we’ll cover the neuroendocrine family that ranges from carcinoids to small cell lung cancer and large cell neuroendocrine carcinomas, the different subtypes of adenocarcinomas, and other aspects of lung cancer pathology.

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3 Responses to Interview with Lung Cancer Pathologist Matthew Horton, Pt 1: Intro to NSCLC Subtypes

  • Rita says:

    Thank you for this! When my husband was diagnosed with “adenocarcinoma of the lung with BAC features,” also stated as “adenocarcinoma of the lung compatible with BAC,” my husband and I were terribly confused. Initially, we were under the impression that BAC was a cancer separate from adenocarcinoma, and when we were then told he had “both,” or a “mixed type,” we got terribly confused. This presentation has clarified a lot of this for us.

  • LovesLife says:

    Very interesting read! Thanks Dr. Horton – looking forward to the rest of the series.

    Linda

  • Catharine says:

    Dr. Horton and Dr. West:

    Thank you for an interesting presentation.

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