Expert Round Table with Drs. Hensing & Jackman: Molecular Markers & Sequence of Therapy for Stage IV Lung Adenocarcinoma


   The second part of my conversation with Drs. Tom Hensing from North Shore Health System in Chicago and David Jackman from Dana Farber Cancer Institute in Boston covered a case of a relatively young, generally healthy woman diagnosed with a lung adenocarcinoma that turned out to be stage IV.  

   Here, we discuss our priorities for molecular testing and how the results of EGFR, KRAS, and EML4-ALK testing would alter our clinical recommendations.  We then discuss the options for this patient, with special focus on how long to continue first line therapy and when and how to transition off of first line treatment into either observation or maintenance therapy.

   Here’s the audio and video podcasts of the discussion, along with the transcript and figures.

drs-hensing-and-jackman-molec-testing-sequence-of-rx-case-2-audio-podcast

drs-hensing-and-jackman-molec-testing-sequence-of-rx-case-2-transcript

drs-hensing-and-jackman-molec-testing-sequence-of-rx-case-2-figures

   This program was sponsored by OSI Pharmaceuticals, who had no input in its content.  We appreciate their support in making this activity possible.

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Posted in: Anti-angiogenic agents, Chemotherapy, Clinical Cases, EGFR mutations and other molecular markers, Epidermal growth factor receptor (EGFR)-based therapies, First-line treatment, GRACEcast, Maintenance therapy, Non-Small Cell Lung Cancer (NSCLC), Stage IV/Advanced/Metastatic NSCLC, Targeted therapies, Treatment, Webinars