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Surgery for Small Cell Lung Cancer?

June 29, 2008 - 1:19 pm

   One topic that is rarely considered in the management of SCLC is the role of surgery.  The main reason is that the vast majority of patients presenting with SCLC either have extensive disease that has spread throughout the body (2/3 of SCLC presentations) or at least already have rather bulky nodal disease that would […]

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Treating Elderly and Poorer Performance Status Patients with Small Cell Lung Cancer

August 28, 2007 - 9:18 pm

  The fact is that lung cancer, like many others, is a disease disproportionately affecting older populations, with the median age now in the 69-70 range.
 (Click to enlarge)
But our trials in lung cancer only rarely involve patients over 70.  This leaves us with serious questions about the best way to treat older and poor performance […]

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Prophylactic Cranial Irradiation for SCLC

December 2, 2006 - 4:12 pm

   Prophylactic cranial irradiation, or PCI, for SCLC, usually limited disease (LD-SCLC), remains a controversial issue, although this is generally recommended for patients with LD-SCLC who have a complete response to treatment (no evidence of disease).   However, the idea of radiating the brain of someone who has no evidence of cancer there and may never […]

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Current Standards of Care for Limited Disease SCLC

December 1, 2006 - 4:32 pm

  While SCLC accounts for only about 13% of lung cancer, and only approximately one third of patients with SCLC have limited disease SCLC (LD-SCLC), this remains a high stakes area with the potential for being cured, so it needs to be treated as optimally as possible.  I’m going to give a brief history and highlight […]

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Small Cell Lung Cancer 101: An Introduction

November 24, 2006 - 3:25 pm

   After several weeks of posts on other aspects of lung cancer, I am long overdue to write on small cell lung cancer (SCLC).  Although it is good to see the number of SCLC cases decreasing over time, and becoming a smaller and smaller percentage of lung cancer cases overall (only about 13% in the […]

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