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Dana Farber Cancer Institute

GRACE Video

Liquid Biopsies: Faster Results, Easier on Patients

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ASCO 2015 Highlights 13

 

Liquid biopsies (also called serum testing) is a practice already approved in Europe for EGFR lung cancer patients. Drawing blood to test for acquired resistance is easier and quicker than needle biopsies. How long until it is standard practice in the US?

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GRACE Video

BRAF: A New Target to Treat in Lung Cancer

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ASCO 2015 Highlights 12

 

A study released at ASCO 2015 showed that the BRAF V600E mutation had a high response rate to combination therapy Tafinlar (dabrafenib) plus Mekinist (trametinib), which led the doctors to agree that BRAF testing in lung cancer should become commonplace.

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GRACE Video

Improved Survival in Malignant Pleural Mesothelioma with Avastin Added to Chemotherapy

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ASCO 2015 Highlights 11

 

A French study presented at ASCO 2015 showed a survival benefit with Avastin (bevacizumab) added to standard chemo, unlike a prior US study. The doctors discuss the influence of this trial and future potential benefits from immunotherapy in mesothelioma.

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GRACE Video

Which Patients with Lung Cancer Should Receive Whole Brain Radiation Therapy?

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ASCO 2015 Highlights 10

 

Managing brain metastases is a big concern for lung cancer patients. The doctors discuss the drawbacks of whole brain radiotherapy and the fact that there are still unknowns regarding more targeted stereotactic radiosurgery.

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GRACE Video

Can We Do Better with a New Chemotherapy for Squamous Cell NSCLC?

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ASCO 2015 Highlights 09

 

A Japanese study of squamous cell carcinoma showed value in nedaplatin vs cisplatin/Taxotere (docetaxel). But with differences in how Asian versus Caucasian patients metabolize chemotherapy, can we presume this benefit would exist for everyone?

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