GRACE :: Lung Cancer

EGFR

AZD9291 for Acquired Resistance in EGFR Positive Lung Cancer

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EGFR positive lung cancer patients who had seen cancer progression responded well to a new drug in an early clinical trial.

AZD9291: Response rate in T790M+ (central test)


Does Gilotrif Help EGFR Positive Lung Cancer Patients?

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An analysis of two large studies of EGFR lung cancer patients tried to determine if Gilotrif helped patients live longer.

Combined OS analysis: mutation categories


Does Adding Avastin to Tarceva Help EGFR Positive Lung Cancer Patients?

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Drs. Nasser Hanna, Melissa Johnson and Jack West discuss results of a phase 2 trial presented at ASCO 2014 that studied if adding Avastin (bevicizumab) to Tarceva helped EGFR positive lung cancer patients increase progression-free survival. June 2014.

Primary endpoint: PFS by independent review


How Do We Make EGFR Inhibitors Work Better for Patients

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Dr. Geoffrey Oxnard of Dana-Farber Cancer Institute describes what research indicates may be more successful treatments for EGFR lung cancer patients.


Why Are Non-Mutated EGFR Genes Called “Wild Type?”

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When it comes to EGFR and lung cancer, is a mutation good or bad? Dr. Joel Neal of Stanford University Medical Center explains why non-mutated genes are called “wild type.” February 2014.


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