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Dr West

Brief Video: Systemic Therapy Alternative to Radiation for Multiple Brain Metastases?

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In most situations where a patient is diagnosed with multiple brain metastases in the setting of a new lung cancer, the recommended treatment will be radiation, often whole brain radiation (WBR).  But even if that’s the general rule, there are sometimes cases in which there’s good reason to consider making an exception.  Here’s my brief discussion of a case scenario in which I consider it a strong option to try systemic therapy before initiating brain radiation, and why I consider it to be an exception:

I’d be very interested in your comments and questions.  Would you want to try systemic therapy first or favor the default option of brain radiation as initial treatment?


One Response to Brief Video: Systemic Therapy Alternative to Radiation for Multiple Brain Metastases?

  • katiejolove says:

    Dr. West this was a great video. I wish my Dad could have had a systemic therapy proven to cross bbb at his diagnosis and then we could have saved the wbr for future treatment. Unfortunately because he isn’t EGFR or ALK positive, there aren’t many options for him. For the last two years he’s had zero chemo and NED outside the brain, but for some reason keeps getting a handful of brain mets about every ten months on average. The only other chemo I know of that seems to be somewhat effective in getting across the bbb could be Alimta. I hope if we reach the point where the number of brain mets surpasses the max SRS can treat we have something systemic to work. Thanks again for the post.

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