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Dr West

Is it safe to give Tarceva with whole brain radiation for lung cancer patients with brain metastases?

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This question of the safety of giving Tarceva (erlotinib) along with brain radiation comes up in our clinics.  In general, cancer docs tend to be conservative about giving anti-cancer therapies concurrent with brain radiation unless we have a good sense of its safety.  This video talks about the question and the findings from a series of 40 patients from MD Anderson who provide an answer that can help guide us in the future.


Dr West

Brief Video: Systemic Therapy Alternative to Radiation for Multiple Brain Metastases?

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In most situations where a patient is diagnosed with multiple brain metastases in the setting of a new lung cancer, the recommended treatment will be radiation, often whole brain radiation (WBR).  But even if that’s the general rule, there are sometimes cases in which there’s good reason to consider making an exception.  Here’s my brief discussion of a case scenario in which I consider it a strong option to try systemic therapy before initiating brain radiation, and why I consider it to be an exception:

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Dr West

Dr. Mehta on New Technologies in Radiation for Lung Cancer

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Somehow I posted the last podcast from Dr. Mehta’s presentation on New Developments in Radiation Oncology for Lung Cancer but overlooked part 5 that should have preceded it. Here’s that longer portion that covers several new advances in the technologies now being incorporated into radiation therapy for lung cancer.

Here’s the video and audio versions of his podcast, along with the associated transcript and figures.

Mehta Refining RT for LC Pt 5 New Technologies Audio Podcast

Mehta Refining RT for LC Pt 5 New Technologies Transcript

Mehta Refining RT for LC Pt 5 New Technologies Figures

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Dr West

Dr. Mehta on Moving Radiation Developments into Metastatic Lung Cancer

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Finishing his presentation on new techniques in radiation oncology being applied to lung cancer, Dr. Vivek Mehta turns to the setting of metastatic lung cancer and the potential though still debatable utility of focused radiation to treat oligometastatic disease (metastatic, but with very limited spread of the cancer). Here’s the last podcast from his presentation, in both video and audio formats, along with the associated transcript and figures.

Mehta Refining RT for LC Pt 6 Moving Developments into Metastatic LC Audio Podcast

Mehta Refining RT for LC Pt 6 Moving Developments into Metastatic LC Transcript

Mehta Refining RT for LC Pt 6 Moving Developments into Metastatic LC Figs

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Dr West

Defining a Role for Sterotactic Radiosurgery in Lung Cancer: Podcast 4 by Dr. Mehta

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Here’s part 4 of the presentation by Swedish Cancer Institute radiation oncologist Dr. Vivek Mehta, in which he provides additional data supporting a growing role for stereotactic radiosurgery, also referred to as stereotactic body radiation therapy (SBRT) in lung cancer.  There is discussion of the data supporting its role in medically inoperable patients and also consideration of extending its use to patients able to tolerate surgery, so now asking whether SBRT can substitute for the historical “gold standard” of surgery in patients who would otherwise undergo resection. 

Below you’ll find the video and audio versions of the podcast, along with the transcript and figures.

Mehta Refining RT for LC Pt 4 Defining Role for SBRT Audio Podcast

Mehta Refining RT for LC Pt 4 Defining Role for SBRT Transcript

Mehta Refining RT for LC Pt 4 Defining Role for SBRT Figures

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