GRACE :: Radiation Oncology


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Dr West

Is it safe to give Tarceva with whole brain radiation for lung cancer patients with brain metastases?


This question of the safety of giving Tarceva (erlotinib) along with brain radiation comes up in our clinics.  In general, cancer docs tend to be conservative about giving anti-cancer therapies concurrent with brain radiation unless we have a good sense of its safety.  This video talks about the question and the findings from a series of 40 patients from MD Anderson who provide an answer that can help guide us in the future.

Dr West

Brief Video: Systemic Therapy Alternative to Radiation for Multiple Brain Metastases?


In most situations where a patient is diagnosed with multiple brain metastases in the setting of a new lung cancer, the recommended treatment will be radiation, often whole brain radiation (WBR).  But even if that’s the general rule, there are sometimes cases in which there’s good reason to consider making an exception.  Here’s my brief discussion of a case scenario in which I consider it a strong option to try systemic therapy before initiating brain radiation, and why I consider it to be an exception:

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