68 years old,diagnosis with Brain cancer

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January 11, 2017 at 12:38 am  #1289756    


Reoprt as follows,
Site: Biopsy from left thalamic SOL: Left thalamic SOL ? High grade glioma
Received multiple very small floating bits, greyish white, measuring 0.1 cm, weighing 0.5gm – A/E
Sections studied show, glial tissue with foci of choroid plexus elements with papillary fronds lined by single layer of epithelial cells. Multiple foci of calcification seen. Also seen a tiny fragment of tissue showing papillary architecture with multiple layers of cells showing atypical features. Cells show enlarged, anisocytic nucleus, hyperchromasia,inconspicuous nucleoli and scanty cytoplasm.
1HC :
CK7 – Few tumor cells are positive.
CK20 – Negative.
CD10 – Negative.
TTF1. Positive on tumor cells.
Ki67 – High (10-12%)
Evidence of 4.0 x 3.8 x 3.5 cm mesring T1 hypointense, T2 ‚ÄĘhyperintese lelsion with surrounds
edema noted in the left thalamus
Mass effect seen in thefor of compression of left lateral ventricles.
Midline shift towards right side measuring 4 mm noted.
left uncal hernaiton noted.
Post contrast sudy shows peripheral nodular rim enhancment with heterogeneous enhancement noted
No evidence of diffusion restriction, no evidence of GRE blooming noted.
CT scan brain:
Evidence of ring enhancing mass measuring about 3.7 x 3.4cm seen in left thalamus , surrounding edema noted.
Mass effect over left side ventricular system noted, midline shift to right about 7mm
B rainstem and cerebellum appear normal
B oth orbits and paranasal sinuses appear normal
USG Neck:
Right lobe of thyroid meausres 3.8 x 1.4 x 1.2 cm.Vol.3.5cc
Left lobe of thyroid measures 2.7 x 1.0 x 1.4 cm.Vol.2.1cc
Isthmus measures 1.4mm.
Both lobes of thyroid and Isthmu
appear normal in size and echotexture
Right lobe shows a hypoechoic nodules measuring about 2mm.
Left lobe shows few hypoechoic nodules largest nodule measuring about 6mm
Suggestive of Benign nodules
No significant lymphadenopathy

January 11, 2017 at 6:49 am  #1289757    
JimC Forum Moderator
JimC Forum Moderator

Hi nandhini,

Welcome to GRACE. I’m sorry that you have received these very worrisome scan results. We would like to be able to help, but unfortunately we do not currently have an expert in primary brain cancer on our faculty. In addition it is beyond the scope of this site to provide an interpretation of these reports, especially in the complex situation described here.

I hope that very soon you will be able to meet with your local doctor to discuss the findings. Since the situation is complicated, you may also want to consider a second opinion.

Good luck.

Forum moderator

Jul 2008 Wife Liz (51/never smoker) Dx Stage IV NSCLC EGFR exon 19
4 cycles Carbo/alimta, 65% shrinkage
Tarceva maintenance
Mar 2010 progression, added Alimta, stable
Sep 2010 multiple brain mets, WBR
Oct 2010 large pericardial effusion, tamponade
Jan 2011 progression, start abraxane
Jun 2011-New liver, brain mets, add Tarceva
Oct 2011-Dx Leptomeningeal carcinomatosis; pulsed Tarceva
At rest Nov 4 2011
Since then: http://cancergrace.org/blog/jim-and-lisa

January 11, 2017 at 7:46 am  #1289759    


If you’d like to join a support group, the American Brain Tumor Association has one on inspire.com.
Just go to the site and join and you can post, search or just read. Wishing you the best.
Take care, Judy

Stage IIIA adeno, dx 7/2010. SRS then chemo carbo/alimta 4x. NED as of 10/2011.
Local recurrence, surgery to remove LRL 8/29/13. 5.2cm involved pleura. Chemo carbo/alimta x3. NED

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