Will an abdominal tap/paracentesis scheduled a few days after a keytruda/pembrolizumab infusion (for lung cancer) reduce the effect of the immunotherapy? I’m worried that taking a bunch of fluid out only a few days after the immunotherapy infusion will somehow effect how the immunotherapy is building up in the body. (That will only be keytruda infusion #2.)
Welcome to GRACE. Since treatments such as immunotherapy and chemotherapy are systemic, they are at work against cancer cells throughout the body, wherever they may be found. As a result, removing built-up fluid (or any other portion of the body) should have no impact on the efficacy of that treatment.
I hope you get great, long-lasting results from Keytruda!
Jul 2008 Wife Liz (51/never smoker) Dx Stage IV NSCLC EGFR exon 19
4 cycles Carbo/alimta, 65% shrinkage
Mar 2010 progression, added Alimta, stable
Sep 2010 multiple brain mets, WBR
Oct 2010 large pericardial effusion, tamponade
Jan 2011 progression, start abraxane
Jun 2011-New liver, brain mets, add Tarceva
Oct 2011-Dx Leptomeningeal carcinomatosis; pulsed Tarceva
At rest Nov 4 2011
Since then: http://cancergrace.org/blog/jim-and-lisa