Portal Forums Lung/Thoracic Cancer Lung Cancer Member Updates ADENOCARCINOMA STAGE 2b

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January 15, 2017 at 2:29 pm  #1289805    


Hello! My dad was diagnosed with lung adenocarcinoma ( a 3 cm single nodule on the left lobe) on November. A week later he had a VATS lobectomy. The doctors were very optimistic saying it was stage 1a. The biopsy, however, showed it was a poorly differentiated adenocarcinoma which invades the visceral pleura and extends to parietal pleura- no lymph nodes involved (16 resected),resection margins free ( T3N0 M0 tumor, stage 2b?). The surgreon said he did a great job and he insisted that it was stage I, with no need for adjuvant chemotherapy. However, the oncologist said that my father had to do a three cycle cabo- alimta chemo and 20 radiations to try to prevent local recurrence. My father has already had the first chemo with no side effects. I would like your opinion about radiations. What are the chances of recurrence- local or distant failure? Let me say that my father is 70 years old ex smoker with no other health problems cardiologist said that his heart function is excellent, taking into consideration his age). I’m anxiously waiting for your answer. Thank you in advance

January 15, 2017 at 4:03 pm  #1289806    
JimC Forum Moderator
JimC Forum Moderator

Hi nasos,

Welcome to GRACE. I am sorry to hear of your father’s diagnosis, and I hope that the surgeon is correct that it is indeed stage I. That staging dispute might be settled by obtaining a second opinion, but it’s also true that the chances of recurrence are significantly greater at stage II, and the benefit of chemoradiation is much clearer than at stage I. As Dr. West states, the chance of recurrence “depends on a person‚Äôs stage: the recurrence rate is in the range of 25% for patients with stage I NSCLC, 50% for patients with stage II NSCLC, and around 75% for patients with stage III NSCLC.”

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Jul 2008 Wife Liz (51/never smoker) Dx Stage IV NSCLC EGFR exon 19
4 cycles Carbo/alimta, 65% shrinkage
Tarceva maintenance
Mar 2010 progression, added Alimta, stable
Sep 2010 multiple brain mets, WBR
Oct 2010 large pericardial effusion, tamponade
Jan 2011 progression, start abraxane
Jun 2011-New liver, brain mets, add Tarceva
Oct 2011-Dx Leptomeningeal carcinomatosis; pulsed Tarceva
At rest Nov 4 2011
Since then:

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