Cascade Primed Immune Cells ( CAPRI)

Portal Forums Cancer Treatments / Symptom Management Other Novel Therapies Cascade Primed Immune Cells ( CAPRI)

This topic contains 4 replies, has 4 voices, and was last updated by JimC Forum Moderator JimC Forum Moderator 4 years, 1 month ago.

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May 14, 2013 at 7:28 pm  #1256458    


My father is a adeno lung cancer patient, and I recently visited him in China. While I was there, the hospital where my father is receiving his treatment offered a treatment called “Cascade Primed Immune Cells” (CAPRI ). The brochure said this treatment is invented by Dr.Rudolf Wank from Munich Center of Immunotherapy Germany.

I found very limited information on internet regarding its efficacy in treating lung cancer. I am wonder if anyone has heard of it ? experienced it ? and how you think of it ?

May 14, 2013 at 8:35 pm  #1256467    
Dr West
Dr West

I have never heard of it. I would venture to say that it is not an established or widely recommended treatment at this point.

-Dr. West

May 15, 2013 at 8:47 am  #1256473    


Thank you for the feedback

May 5, 2014 at 5:00 am  #1263606    


I’ve just read about it here:

It seems very promising (but of course, I’m no doctor). A person with Pancoast’s survived for 10+ years after surgery on this therapy. The authors suggests immune cells need to be isolated from blood before chemo for best results.

I wish it was available in my country. But it’s probably very expensive.

May 5, 2014 at 5:31 am  #1263608    
JimC Forum Moderator
JimC Forum Moderator

Hi andrius,

Anecdotal evidence from four patients is not especially helpful to determine whether a particular treatment has been successful, especially when those patients were also treated with either surgery, radiation or chemotherapy, or some combination of those therapies. Only a clinical trial, in which a number of patients with similar situations are randomized to receive either the trial therapy or an alternate (or placebo), can provide solid evidence of that treatment’s efficacy.

I should also point out that the first sentence of the report (“Despite newer treatment modalities, few patients with non-small cell lung cancer in stages IIIB and IV survive the median of one year.”) is not at all accurate – the median survival for stage IV patients is near a year, and that means that half survive longer than a year, a fact that should be well known to the authors of the study.

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Jul 2008 Wife Liz (51/never smoker) Dx Stage IV NSCLC EGFR exon 19
4 cycles Carbo/alimta, 65% shrinkage
Tarceva maintenance
Mar 2010 progression, added Alimta, stable
Sep 2010 multiple brain mets, WBR
Oct 2010 large pericardial effusion, tamponade
Jan 2011 progression, start abraxane
Jun 2011-New liver, brain mets, add Tarceva
Oct 2011-Dx Leptomeningeal carcinomatosis; pulsed Tarceva
At rest Nov 4 2011
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