Evaluating pleural effusion response to Xalkori

Portal Forums Lung/Thoracic Cancer Lung Cancer Complications Pleural Effusions Evaluating pleural effusion response to Xalkori

This topic contains 30 replies, has 10 voices, and was last updated by  catdander forum moderator 1 year, 4 months ago.

Viewing 11 posts - 21 through 31 (of 31 total)
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February 11, 2013 at 8:38 pm  #1253683    

Dr West

That’s really good to hear. It’s not uncommon to have a hard time getting a good read on the response from imaging, but if things aren’t progressing, it’s possible that you will continue to do well and feel pretty well for a long time. Here’s to more good news in the future.

-Dr. West


Howard (Jack) West, MD
Medical Oncologist

Views expressed here represent my opinion, not those of GRACE or Swedish Cancer Institute. This information does not constitute medical advice and is intended to supplement and not replace medical information provided by your doctor.

February 13, 2013 at 8:04 am  #1253724    

aunttootsie001

Okay is this just making me feel better or will it actually do some good? I’ve decided to take my Morning Xalkori on more of an empty stomach. Yesterday I just took one spoonful of Yogurt and then took my pill with some warm Coffee. Then I waited over and hour to eat the rest of the Yogurt. I’ve been on the 200mg’s of Xalkori twice a day since a week today. Had labs this past Monday and no word from the Center so I’m assuming I am in range with my Liver enzymes so that’akes me happy! But I’m anxious to start seeing more results with riding the Wheezing as it makes it difficult to sleep at night. Drives me crazy. I think I look tired. So do you think I’m being silly by doing this? By the way no upset tummy, no nausea either. I usually wait two hours before having cereal. Silly Me= Lorrie.


DX June 2011, Non smoker. Lobectomy August. 2011. Two TX Carbo/Taxol. 31 TX Radiation 2012. Break no treatment 8mo. Malignant Pleural Effusion discovered Oct. 2012. Xalkori started Nov. 2012. Pleurodisis done April 2013. Last CT still NED.

February 13, 2013 at 8:34 pm  #1253738    

Dr West

I think as long as you’re able to keep it down well and your liver function tests are doing well, whatever you’re doing is great.

-Dr. West


Howard (Jack) West, MD
Medical Oncologist

Views expressed here represent my opinion, not those of GRACE or Swedish Cancer Institute. This information does not constitute medical advice and is intended to supplement and not replace medical information provided by your doctor.

February 14, 2013 at 6:58 am  #1253744    

aunttootsie001

But am I getting the full affect of the meds this way apposed to taking it with food which I heard reduces the effectiveness to 85%? Thanks Dr. West?


DX June 2011, Non smoker. Lobectomy August. 2011. Two TX Carbo/Taxol. 31 TX Radiation 2012. Break no treatment 8mo. Malignant Pleural Effusion discovered Oct. 2012. Xalkori started Nov. 2012. Pleurodisis done April 2013. Last CT still NED.

February 14, 2013 at 10:22 am  #1253751    

Dr West

A high fat meal can reduce absorption by about 15%, but otherwise, food hasn’t been demonstrated to exert a significant effect on absorption of XALKORI, except for grapefruit juice, which should be avoided while on XALKORI and many other orally absorbed cancer medications.

-Dr. West


Howard (Jack) West, MD
Medical Oncologist

Views expressed here represent my opinion, not those of GRACE or Swedish Cancer Institute. This information does not constitute medical advice and is intended to supplement and not replace medical information provided by your doctor.

February 14, 2013 at 10:26 am  #1253753    

catdander forum moderator

Lorrie, I’m wondering if the last 4 posts would be better served to the public on the ALK/ROS user group thread. What do you think?
Janine
forum moderator


My husband, 53 @ dx of stage 3 squam nsclc R. pancoast tumor 8/09 caused destruction of 3 ribs, touching brachial plexus. 2 core and 1 VATS undx biopsies. Open thoracotomy for 1 positive biopsy (unresectable). Chemorads, 9/09. MRI by pancoast specialty surgeon 11/09 spine met found, stage IV, Rad to spine, Chemo changed from cis/etop to navelbine/carbo. 6 cycles total. Tarceva 2/10-11/10. 3cm tumor L lung, biopsy undx w/collapsed lung. Gemzar, 12/10 through 7/12. NED 3/12, stop tx 7/12. Remains NED as of 2/14.

March 5, 2013 at 9:15 pm  #1254502    

aunttootsie001

Janie I’m sorry if I posted in the wrong area I was just conversing with James. The subject of Pleural Effusion didn’t get talked about in the ALK pages here one thing leads to another? I don’t know how to move them?


DX June 2011, Non smoker. Lobectomy August. 2011. Two TX Carbo/Taxol. 31 TX Radiation 2012. Break no treatment 8mo. Malignant Pleural Effusion discovered Oct. 2012. Xalkori started Nov. 2012. Pleurodisis done April 2013. Last CT still NED.

March 6, 2013 at 6:02 am  #1254504    

huiyuan49

I have a small pleural effusion due to my right low lobe lobectomy. I hope it is gone.

I searched a Chinese web found that the doctors at a medical college hospital in Fujian Province, inject warm physiologic saline into the place, where pleural effusion was. They use warm physiologic saline to wash and circulate there in some cases plus antibiotics locally used getting unbelievable results including in some stage iv patients.

The document is in Chinese published in a medical journal.

I can paste a part of the article here, if interested in it.

March 6, 2013 at 8:03 am  #1254508    

catdander forum moderator

Lorrie, really really not trying to make this difficult or be a tight a… When I read through the threads I look at them as pieces of information that will help a great deal of people. In doing so Dr. West has ask that we keep topics separate so subjects are easily found by readers everywhere not just those writing. I felt your conversation with the doctors about eating prior to taking xalkori warranted its own place. I’ll leave it and add a tag about it so those doing a search will find it.

As a contributing member don’t hesitate to start a new thread or add to a general one like the xalkori user group.

Above all don’t worry too much about it when trying to get your questions out. I’ll just let you know if I split up a conversation if I think it warrants it’s own thread.

I hope that makes sense and thanks for bringing up these subjects they are helpful to so many.
Janine


My husband, 53 @ dx of stage 3 squam nsclc R. pancoast tumor 8/09 caused destruction of 3 ribs, touching brachial plexus. 2 core and 1 VATS undx biopsies. Open thoracotomy for 1 positive biopsy (unresectable). Chemorads, 9/09. MRI by pancoast specialty surgeon 11/09 spine met found, stage IV, Rad to spine, Chemo changed from cis/etop to navelbine/carbo. 6 cycles total. Tarceva 2/10-11/10. 3cm tumor L lung, biopsy undx w/collapsed lung. Gemzar, 12/10 through 7/12. NED 3/12, stop tx 7/12. Remains NED as of 2/14.

March 6, 2013 at 8:13 am  #1254510    

aunttootsie001

Sorry again Janie, I wasn’t upset just remarking I’m not able to transfer my subject but now that you mention it the title of this blog is Evaluating response to Xalkori so maybe we could transfer the whole thread? But really I am fine and will be more observant! Your friend Lorrie


DX June 2011, Non smoker. Lobectomy August. 2011. Two TX Carbo/Taxol. 31 TX Radiation 2012. Break no treatment 8mo. Malignant Pleural Effusion discovered Oct. 2012. Xalkori started Nov. 2012. Pleurodisis done April 2013. Last CT still NED.

March 6, 2013 at 8:47 am  #1254511    

catdander forum moderator

Got it thanks for the reply. I don’t think you are able to move or split threads. That’s why I asked if you minded if I did it. I don’t think there’s anything wrong with making separate threads about xalkori. Especially if it pertains to a particular question. One huge thread could get confusing when looking for something specific like the question here about pleural effusions.
There’s also the forum specific to ALK inhibitors http://cancergrace.org/forum/cancer-treatments-symptom-management/alk-inhibitors
I always try to direct posters of these threads to the xalkori user group.
I know this is a mistake and shouldn’t bother me…but as a child it always when new teachers/adults miss pronounced my name. Janie was the typical mistaken pronunciation to Janine. Now I’m absolutely floored by how many people with my name there are on facebook. Pages of them.
How’s that for getting off topic. :-P


My husband, 53 @ dx of stage 3 squam nsclc R. pancoast tumor 8/09 caused destruction of 3 ribs, touching brachial plexus. 2 core and 1 VATS undx biopsies. Open thoracotomy for 1 positive biopsy (unresectable). Chemorads, 9/09. MRI by pancoast specialty surgeon 11/09 spine met found, stage IV, Rad to spine, Chemo changed from cis/etop to navelbine/carbo. 6 cycles total. Tarceva 2/10-11/10. 3cm tumor L lung, biopsy undx w/collapsed lung. Gemzar, 12/10 through 7/12. NED 3/12, stop tx 7/12. Remains NED as of 2/14.

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