Is Intrathecal Pump An Exclusion From Clinical Trial NSCLC?

Portal Forums Cancer Basics Clinical Trials and Drug Development Is Intrathecal Pump An Exclusion From Clinical Trial NSCLC?

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July 21, 2016 at 7:35 am  #1274753    


Im asking for my son in law who has stage 4A NSCLC Adenocarcinoma. He is having a very hard time getting his pain under control as the cancer has entered his pleural space. Drs are looking into an intrathecal pump and I wanted to ask if this pump could possibly exclude him from a clinical trail? It will administer pain medication only, not cancer treatment medication.
Original Dx May 2015, original tumor gone from radiations as used as second line. Cancer is now in Pleura and inoperable, has not spread to any other organs. Has received 2 rounds of chemo and 1 attempt at afatinib none of these worked. He is HER2 mutation positive.
Thank you for your help and attention!!

July 21, 2016 at 5:28 pm  #1274758    
JimC Forum Moderator
JimC Forum Moderator

Hi Wendy,

Welcome to GRACE. I’m sorry to hear that your son’s pain has been so difficult to control. I haven’t seen the use of such a pump specifically listed as an exclusion for a clinical trial, but that might be something that would be decided on a trial-by-trial, or patient-by-patient manner.

If there are specific trials in which you might be interested, it might help to contract the trial coordinators of each to discuss whether this would be an exclusionary factor.

Forum moderator

Jul 2008 Wife Liz (51/never smoker) Dx Stage IV NSCLC EGFR exon 19
4 cycles Carbo/alimta, 65% shrinkage
Tarceva maintenance
Mar 2010 progression, added Alimta, stable
Sep 2010 multiple brain mets, WBR
Oct 2010 large pericardial effusion, tamponade
Jan 2011 progression, start abraxane
Jun 2011-New liver, brain mets, add Tarceva
Oct 2011-Dx Leptomeningeal carcinomatosis; pulsed Tarceva
At rest Nov 4 2011
Since then:

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