Metastatic Breast Cancer Help

Portal Forums Q&A, Ask Us New Questions Metastatic Breast Cancer Help

This topic contains 3 replies, has 2 voices, and was last updated by catdander forum moderator catdander forum moderator 2 days, 11 hours ago.

Viewing 4 posts - 1 through 4 (of 4 total)
Author Posts   
Author Posts
April 15, 2018 at 10:45 pm  #1294236    
mimianne
mimianne

Original BC Dx 10/2011, (50yrs old) had Bilateral Mx, IDC, grade 1, 6cm (couldn’t feel it, made up of clusters). ER+ PR+ HER2-. Sentinel node appeared ok, but Path came back positive for micro cells. Onc said chemo should take care of them. 4 rounds Taxotere/Cytoxan, put me into menopause, took Tamoxifen 1 1/2yrs, then due to DVT, switched to Anastrozole for 3 1/2yrs. 1yr after Mx, had Thoracic Laminectomy to remove Meningioma Tumor pressing on spinal cord T5 level. I Suffer tremendously from PMPS and Post Laminectomy Pain Syndrome, on ER Morphine 24/7. All treatments are hard on me, I’m already so compromised. I’m obese, scans say sub-optimal.
4/2017 Dx MBC, 1mo after finishing Anastrozole, unrelated CT found enlarged R Axillary Nodes, biopsy confirmed IDC grade2 ER+PR- HER2-. I’d been having soreness there, but figured it was just part of my chronic pain. PET/CT also showed Mediastinal nodes, ParaTracheal node & Scapula lesion. Did 4mo Xeloda, follow up PET/CT showed some slightly better/some slightly worse & new multiple scattered bilateral pulmonary nodules, too small to biopsy. Started on Ibrance and Faslodex. After 6 cycles, PET/CT again showed some slightly better/some slightly worse. For over a yr now have had increasing pain/nerve/numbness issues from R Axillary, shoulder, down to fingers. Unbearable now, so had MRI which showed 4.3 mass adjacent to Brachial Plexus Nerve, and 1.4cm at T1-T2 poss nerve sheath tumor. Drs don’t know why doesn’t show on PET/CT. Just completed radiation to area, hoping for some relief. Also did 1st ever scan on Brain since MBC Dx, MRI showed 1.4cm Met lesion L Frontal Lobe, and 1.2cm L Posterior Cerebellum. Just completed SRS to Brain. No idea how long all these spots have been there! Also having heart issues, SOB, high heartrate. Onc didn’t have a new plan, lightly threw out we could do Gemzar. Or maybe Exemestane, or both. Not confident, very afraid, not sure what to do. What meds cross BBB? Help pls give me options.


11/2011 BC, ER+PR+HER2- Bi-Lat MX, Sentinel Node appeared clean, no more removed, then Path showed Positive for Micro Cancer Cells, 4 Rounds Cytoxan/Taxotere, followed by 1-1/2yrs Tamoxifen, then 3-1/2yrs Arimidex.
5/2017 MBC, ER+PR-HER-, Mets to Axillary, Mediastinal & Pre-Tracheal Nodes, Scapula.
9/2017 Scattered nodules both lungs.
3/2018 1st MRIs found 1.4cm Met lesion L Frontal Lobe, 1.2cm L Posterior Cerebellum, 4.3cm mass@Brachial Plexus, 1.9cm mass@T1-T2.

April 16, 2018 at 12:43 pm  #1294246    
catdander forum moderator
catdander forum moderator

Hi mimianne and welcome to Grace. I’m so sorry you’re suffering so much. I hope you get relief to the pain in your arm. My husband’s tumor involved his bracial plexus too and he still has issues but nothing like it was when found. As for the brain tumors the radiation very possibly killed them so that’s possibly not going to be an issue.

Idon’t know if this will be helpful but does come from a timely and good source. https://am.asco.org/treating-er-positive-her2-negative-metastatic-breast-cancer

I’m sorry but we can’t tell you what you should do or give standard’s of care for such a complicated case but a 2nd opinion at a transition time like this is never a bad idea. A 2nd opinion from a teaching hospital that specializes in breast cancer is a good place to get individualized opinion that can be taken back to your local onc where treatment can be given.

I hope you do well moving forward.
All best,
Janine

April 17, 2018 at 11:27 am  #1294255    
mimianne
mimianne

Thank you for your reply. How did your husband get some relief of the Brachial plexus issues, did he have radiation, or did it shrink from treatments? Also, can you tell me which meds cross the Blood Brain Barrier? And I’m with Kaiser, so I’m not sure if I can get a second opinion outside of them. ~Anne


11/2011 BC, ER+PR+HER2- Bi-Lat MX, Sentinel Node appeared clean, no more removed, then Path showed Positive for Micro Cancer Cells, 4 Rounds Cytoxan/Taxotere, followed by 1-1/2yrs Tamoxifen, then 3-1/2yrs Arimidex.
5/2017 MBC, ER+PR-HER-, Mets to Axillary, Mediastinal & Pre-Tracheal Nodes, Scapula.
9/2017 Scattered nodules both lungs.
3/2018 1st MRIs found 1.4cm Met lesion L Frontal Lobe, 1.2cm L Posterior Cerebellum, 4.3cm mass@Brachial Plexus, 1.9cm mass@T1-T2.

April 18, 2018 at 12:55 pm  #1294257    
catdander forum moderator
catdander forum moderator

Anne,

Don was diagnosed stage III unresectable pancoast tumor. The tumor hadn’t infiltrated the bracial plexus but was pushing on it as well as reaching into a foramen of the spine. He had chemo and chest radiation. It killed the cancer but left an ungodly mess in its place including some muscle atrophy. It was impossible to know what was cancer and what was inflammation or scar tissue. His onc followed with pet scans for a year more before switching to ct alone. His suv stayed quite active in that area for over a year. Today it can be difficult to recover from work and it never doesn’t hurt and we agree it’s a small price to pay to be cancer free.
Technically any chemo drug can but most don’t, I’ll look around.

Viewing 4 posts - 1 through 4 (of 4 total)

You must be logged in to reply to this topic.