Pegfilgrastim and leucocyte number

Portal Forums Member Updates Breast Cancer Member Updates Pegfilgrastim and leucocyte number

This topic contains 2 replies, has 3 voices, and was last updated by  Dr Cianfrocca 3 years, 1 month ago.

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May 26, 2015 at 2:52 am  #1269950    


I have breast cancer. Up to now I had 2 courses of chemotherapy with FEC. After the first course I had febrile neutropenia (12 days after the chemo, Leu were 0,4), agranulocitosis and afterwards – abscess in the breast aroud the impant. My chemo was delayd with 9 days and doses were reduced with 20-25%. The second chemo was on 21.05.15. 2 days after the second chemo, on 23.05.2015, I was applied Neolasta s.c. On 25.05.2015, my leucocytes were 39,9. Today, 26.05.2015, my leucocytes were 26,7. Is this increase ine Leu number “normal”? Is pegfilgrastim reccommended also for the next courses? May be doses increased again if Neolasta is administered?

  • This topic was modified 3 years, 1 month ago by  elbozhko.
  • This topic was modified 3 years, 1 month ago by  elbozhko.
May 26, 2015 at 8:32 am  #1269958    
catdander forum moderator
catdander forum moderator


We have a blog post on the subject I’ve linked to below and I’ve asked a doctor to comment.

I hope you do well with treatment.


May 26, 2015 at 8:56 am  #1269959    

Dr Cianfrocca

Depending on the timing of the CBC, the WBC can be high after Neulasta. While it is typical for neulasta to be given for all courses of the FEC once it is started, it is really an individual decision that your oncologist will need to make based on your clinical condition and the way you tolerate the drug. The same is true for the decision of whether or not to increase the doses of the chemotherapy.
Dr. Cianfrocca

Mary Cianfrocca, D.O., FACP
Director of Breast Cancer Program

Views expressed here represent my opinion, not those of GRACE or Banner MD Anderson Cancer Center. This information does not constitute medical advice and is intended to supplement and not replace medical information provided by your doctor.

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