Prostate Cancer – Liver Metastasis

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July 30, 2017 at 3:22 am  #1291145    


Hello Everyone,

My father was diagnosed with prostate cancer in August 2016. The gleason score at that time was 4+3=7.

Further tests showed that there was no activity in his bones. However, a liver CT scan showed that there were numerous hypodense lesions in the both lobes of his liver.The doctor who performed the CT concluded that there has been metastasis to his liver. As there were no other options doctors performed a surgery to remove his testes and told us that he could live for a few more years without much issues and asked us to test his PSA levels every month. So far PSA levels are normal.

However, I have a few questions now – after going through a lot of reports online, i understand it’s very rare to have liver metastasis without any affect on the bones. Can you please confirm that?

Can there be lesions in the liver because of something else? Without further tests, can the doctors conclude that there is liver metastasis?

Please let me know.


July 30, 2017 at 8:42 am  #1291148    
JimC Forum Moderator
JimC Forum Moderator

Hi Peter,

Welcome to GRACE. I’m sorry to hear of your father’s diagnosis. Currently, we don’t have a prostate cancer expert available on this site, but my research does confirm that isolated liver metastases are rare; usually the cancer has spread to other sites as well.

As with any cancer, the presence of lesions in another organ, in the context of an existing cancer diagnosis, raises high suspicions that the lesions are metastases from the identified cancer. On the other hand, the only way to be certain that the lesions represent metastatic prostate cancer is to obtain a tissue biopsy from the liver lesions and test for prostate cancer cells. Other cancers, such as lung cancer, can metastasize to the liver, or the lesions could be benign, described here.

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Jul 2008 Wife Liz (51/never smoker) Dx Stage IV NSCLC EGFR exon 19
4 cycles Carbo/alimta, 65% shrinkage
Tarceva maintenance
Mar 2010 progression, added Alimta, stable
Sep 2010 multiple brain mets, WBR
Oct 2010 large pericardial effusion, tamponade
Jan 2011 progression, start abraxane
Jun 2011-New liver, brain mets, add Tarceva
Oct 2011-Dx Leptomeningeal carcinomatosis; pulsed Tarceva
At rest Nov 4 2011
Since then:

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