71 year old otherwise healthy female with Stage IVb thymus carcinoma. Carbo/taxol plus mediastinal radiation of 60gy 3 years ago. Healthy since, now with recurrence of mediastinal mass by superior vena cava. Option offered was low dose conventional re-irradiation of mediastinal tumor /area. Would stereotactic radiotherapy be better option for re-irradation of a mediastinal mass? She is asymptomatic to above.
In general, with stereotactic techniques, it is possible to increase dose delivered to the recurrent lesion safely.
How meaningful this is depends on the size/volume of the recurrent lesion. Smaller lesions can be treated to very high doses with stereotactic guidance.
Other variable are important too, in terms of what specific technique is used and how this accounts for variation in location of the recurrent mass with respiration.
With thoracic re-irradiation we usually do use a stereotactic platform.
I hope that helps.
Chris Loiselle, MD
Swedish Cancer Institute
Views expressed here represent my opinion, not those of GRACE or Swedish Cancer Institute. This information does not constitute medical advice and is intended to supplement and not replace medical information provided by your doctor.