Research conflict of interest

Portal Forums Cancer Basics Oncology Economics/Industry/Policy Research conflict of interest

This topic contains 3 replies, has 3 voices, and was last updated by Dr West Dr West 4 years, 5 months ago.

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June 10, 2013 at 9:14 am  #1257151    

daisy1963

From the bit i’m gathering, looks like all significant research is done by for-profit companies with the end result being of course profit. Can anyone direct me towards information regarding what is the National Cancer Institute ‘not doing’ on our behalf.

Sounds like the wolves watching the henhouse and if that is the case I suspect the general public has no idea of the implications of this arrangement. I’ve been researching cancer for 1.5 years on my mothers behalf and am just scratching the surface of how this giant machine works. If it is an issue of tax dollars being redirected so that objective research is conducted on behalf of the American public, then I’d like to understand what the issues are and start my own campaign of being the ‘squeaky wheel’ and trying to get people educated on the issues;

If anyone can provide direction, I would greatly appreciate it; and if I’ve posted on the wrong thread, please advise as well. Warm regards.


Mom, 77 dx 1/12 nsclc stage 1b, nonsmoker; very healthy; large tumor, right lung; one lobe removed; 4 rounds chemo; cisplatin (and something else – don’t recall); summer ’12 odd symtpoms; to neuro; thinking parkinsons’s scan’s clean mri august 12 clean; end of year, rapid decline in mobility; 1/13 mri; large met to brain; removed surgically; radiated with fraction radiation; 5/13 new onc; body scan and EGFR check; mets to brain, liver and spine; Tarceva to start june 1

June 10, 2013 at 12:08 pm  #1257160    
JimC Forum Moderator
JimC Forum Moderator

Hi daisy,

I think it’s a little more complicated than simply drug companies spending money to make a lot more, although that certainly is what they’re after. But most trials are designed by doctors like the GRACE faculty, as they try to advance the knowledge base of cancer treatment. They submit their proposals to a number of different funding organizations, including drug companies. When the sponsor is a drug company, it’s a balancing act – the doctors are after useful information and the drug companies are looking to sell drugs and make money. It’s by no means a perfect system.

As far as the NCI, it has a page on clinical trials including their role as a sponsor: http://www.cancer.gov/cancertopics/factsheet/clinicaltrials/clinical-trials

There is a good series of podcasts on the clinical trial system starting here:

http://cancergrace.org/cancer-101/2013/01/06/clin-trials-ramalingam-pt-1/

There are links to the subsequent podcasts at the bottom of that page.

JimC
Forum moderator


Jul 2008 Wife Liz (51/never smoker) Dx Stage IV NSCLC EGFR exon 19
4 cycles Carbo/alimta, 65% shrinkage
Tarceva maintenance
Mar 2010 progression, added Alimta, stable
Sep 2010 multiple brain mets, WBR
Oct 2010 large pericardial effusion, tamponade
Jan 2011 progression, start abraxane
Jun 2011-New liver, brain mets, add Tarceva
Oct 2011-Dx Leptomeningeal carcinomatosis; pulsed Tarceva
At rest Nov 4 2011
Since then: http://cancergrace.org/blog/jim-and-lisa

June 10, 2013 at 3:26 pm  #1257163    

daisy1963

thank you jim – needed a place to get started on my research;


Mom, 77 dx 1/12 nsclc stage 1b, nonsmoker; very healthy; large tumor, right lung; one lobe removed; 4 rounds chemo; cisplatin (and something else – don’t recall); summer ’12 odd symtpoms; to neuro; thinking parkinsons’s scan’s clean mri august 12 clean; end of year, rapid decline in mobility; 1/13 mri; large met to brain; removed surgically; radiated with fraction radiation; 5/13 new onc; body scan and EGFR check; mets to brain, liver and spine; Tarceva to start june 1

June 10, 2013 at 6:11 pm  #1257169    
Dr West
Dr West

Part of the issue is that the US government used to spend a significant amount of money on funding cancer research, but now most money is spent on pre-clinical, lab-based work and almost nothing on actual patient-level research. This has coincided with more research being funded by private companies, so essentially cancer research is now nearly completely privatized. You can say that it’s the fox guarding the henhouse, and it’s certainly an imperfect system, but the way things have evolved is partly a product of the government no longer wanting to fund cancer research if drug companies will do it instead.

-Dr. West

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