Tagrix vs Tagrisso

Portal Forums Lung/Thoracic Cancer EGFR Inhibitors Tagrix vs Tagrisso

This topic contains 11 replies, has 6 voices, and was last updated by  daxys 1 week ago.

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December 12, 2017 at 1:11 pm  #1293628    

edina81

Dear,

please for support with aim to check experience with Tagrix in threrapy of NSLC stage IV after Tarceva therapy. I have pointed Tagrix as Tagrisso is not available in my country. Any experience with this drug, know this is generic version.
Thank you.

December 12, 2017 at 2:42 pm  #1293629    
JimC Forum Moderator
JimC Forum Moderator

Hi edina81,

Welcome to GRACE. Tagrisso and Tagrix are two of the brand names under which the drug Osimertinib is marketed in different parts of the world. Since this is a recently developed drug, there is no generic form available, and won’t be for quite a while, until the patent for this medication runs out.

As a result, any information you have seen about the efficacy of Tagrisso will apply to Tagrix. Tagrisso has been shown to be effective for patients who have progressed on treatment with Tarceva if they have developed a T790M mutation. If you search this site for the term “Tagrisso” you will find plenty of information regarding its use and efficacy.

JimC
Forum moderator


Jul 2008 Wife Liz (51/never smoker) Dx Stage IV NSCLC EGFR exon 19
4 cycles Carbo/alimta, 65% shrinkage
Tarceva maintenance
Mar 2010 progression, added Alimta, stable
Sep 2010 multiple brain mets, WBR
Oct 2010 large pericardial effusion, tamponade
Jan 2011 progression, start abraxane
Jun 2011-New liver, brain mets, add Tarceva
Oct 2011-Dx Leptomeningeal carcinomatosis; pulsed Tarceva
At rest Nov 4 2011
Since then: http://cancergrace.org/blog/jim-and-lisa

December 15, 2017 at 1:30 am  #1293638    

edina81

Dear Jim,

thank you for the reply. I was little bit concerned about Tagrix as it is generic medicine, and as I work as MD and for years following clinical trials I was skeptic somehow. Is there anybody on this medicine present in some groups for consultation?

Thank for the support in this difficult period.

BR
edina81

December 15, 2017 at 10:48 am  #1293639    
catdander forum moderator
catdander forum moderator

edina81,

There aren’t many members at this time on Grace who chat on this forum, though it would be great if there were. Forums such as Lungevity that have a large member community that would probably have members who take Osimertinib under the brand name tagrix. As Jim said both tagrix and tagrisso are the same drug, osimertinib so info on tagrix should look exactly like info on tagrisso.

I hope you do very well.
All best,
Janine

January 11, 2018 at 11:32 am  #1293761    

jasonhay

I developed resistance to Erlotinib, which served me well for three years. I now have 4 months with Osimertinib and I feel much better, the side effects of diarrhea and rash are more tolerable and showed improvement to the RX. I can not afford for TAGRISSO, but Tagrix is almost the same as. Hope more people know the cheap Tagrix.

January 11, 2018 at 2:30 pm  #1293765    
catdander forum moderator
catdander forum moderator

I’m sure tagrix isn’t avialable in the US and other countries who follow the same patent laws.
I’m so glad you are getting the drugs you need and know you are thrilled to be rid of the worst of the side effects. Hope you are on this for a long long time.

All best,
Janine

January 11, 2018 at 6:21 pm  #1293767    

jasonhay

Thank you so much for your kindly and detailed reply.
Edit by Janine, “I’m so sorry but I have to edit out the link but I’m sure anyone who doesn’t have access to the brand name can use what has already been given or better yet talk to your doc or one of their team to help you get the treatment you need.”

January 15, 2018 at 5:34 am  #1293793    

edina81

Dear all,
thank you for the support and advises, appreciate it so much. I have investigated a lot among those two medicines, and generic compound is same, so no medical issues to take it. We already ordered generic drug directly from the manufacturer and I will keep you updated on progress.
Hope this will help. God bless all of us! E.

January 15, 2018 at 7:47 am  #1293795    
catdander forum moderator
catdander forum moderator

Thank you for the update edina81 and best of luck on your new treatment.

Janine

July 12, 2018 at 1:22 am  #1294872    

nagraj1970

Hi edina81 – Is there any further update on progress. Thanks

July 12, 2018 at 1:59 am  #1294873    

edina81

Hi, I do not know what to answer. He has been given 4 cycle Alimta+ Cisplatin after Tarceva, started with Tagrix month ago. Hope medicine will work as for now it is too early. I have contacted manufacturer, found some web sites, checked Bangladesh Drug Agency- seems it is legal and OK. Would realy like to know more,and others experience as for us it is too early to share any valuable info. Anybody with additiinal info?

July 12, 2018 at 12:11 pm  #1294875    

daxys

Some people from inspire.com

https://www.inspire.com/groups/american-lung-association-lung-cancer-survivors/discussion/tagrisso-with-out-prescription-from-us-provider/?page=2#replies

are using Tagrix with success – Satsbefast, YunC (whose mum also took generic Irressa with success for 1-2 years, now she has been on Tagrix for 1-2 years) , Brtmnbs (his wife had a really great response on Tagrix, it almost cleared her lungs). I checked with those people before buying Tagrix for my mum. YunC told me that in China most people use generics.
My mum has been on Tagrix just for a couple of days. But unfortunately for her mutation (G719X) osimertinib does not seem that promising. We have to hope for some luck. If osimertinib does not work, I will have to buy generic Afatinib I guess (I will need to get some references for it first)

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