Tarceva and ammonia levels

Portal Forums Lung/Thoracic Cancer EGFR Inhibitors Tarceva and ammonia levels

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February 5, 2018 at 10:22 am  #1293921    

nancycarol

Has there been any correlation between taking Tarceva and increased in blood ammonia levels? I have a sister, age 61 who has vulvar cancer stage IV and she recently started taking Tarceva as of January 21st. She was sent to the ER for possible stroke but that has been ruled out. Only abnormal was her ammonia level.

February 6, 2018 at 6:24 am  #1293925    
JimC Forum Moderator
JimC Forum Moderator

Hi nancycarol,

Welcome to GRACE. I am sorry to hear of your sister’s diagnosis. I have not seen any scholarly discussion of Tarceva and elevated ammonia levels, here on GRACE or elsewhere.

I hope that your sister responds well to Tarceva for a long time.

JimC
Forum moderator


Jul 2008 Wife Liz (51/never smoker) Dx Stage IV NSCLC EGFR exon 19
4 cycles Carbo/alimta, 65% shrinkage
Tarceva maintenance
Mar 2010 progression, added Alimta, stable
Sep 2010 multiple brain mets, WBR
Oct 2010 large pericardial effusion, tamponade
Jan 2011 progression, start abraxane
Jun 2011-New liver, brain mets, add Tarceva
Oct 2011-Dx Leptomeningeal carcinomatosis; pulsed Tarceva
At rest Nov 4 2011
Since then: http://cancergrace.org/blog/jim-and-lisa

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