TTField: 4th Modality of Treating Cancer

Portal Forums Cancer Treatments / Symptom Management Other Novel Therapies TTField: 4th Modality of Treating Cancer

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December 4, 2015 at 7:26 pm  #1272020    


This 2011 TED Talk might be of interested to the community: Tumor Treating Field

Learned about this from a business channel. Since 2011, there is a company called Novacure that has treatments approved by FDA for Recurrent Glioblasoma and Newly Diagnosed Glioblastoma (brain cancer) and has phase 1 or 2 trials for a variety of cancers, including Non Small Cell Lung Cancer. One can also easily wonder whether this will work for situations where cancers traveled to brain.

December 5, 2015 at 7:03 am  #1272021    
JimC Forum Moderator
JimC Forum Moderator

Thanks for the link.

This modality was discussed a few years ago here at GRACE and although clinical trials continue, there hasn’t been much of anything on it since.

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Jul 2008 Wife Liz (51/never smoker) Dx Stage IV NSCLC EGFR exon 19
4 cycles Carbo/alimta, 65% shrinkage
Tarceva maintenance
Mar 2010 progression, added Alimta, stable
Sep 2010 multiple brain mets, WBR
Oct 2010 large pericardial effusion, tamponade
Jan 2011 progression, start abraxane
Jun 2011-New liver, brain mets, add Tarceva
Oct 2011-Dx Leptomeningeal carcinomatosis; pulsed Tarceva
At rest Nov 4 2011
Since then:

December 5, 2015 at 8:30 am  #1272022    


The company Novocure now has two treatments approved by FDA and are doing clinical trials on a variety of cancers., with non small cell lung cancer (mestease to the brain) completed phase 2. So hopefully, the modality is now more than just a proof of concept.

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