GRACE :: Lung Cancer

What’s the Status and Potential Utility of Cabozantinib in Lung Cancer?

Dr. Heather Wakelee of Stanford University Medical Center discusses whether or not cabozantinib – a drug already approved for thyroid cancer – can help patients with lung cancer. February 2014.


MK-3475 and its Efficacy in Lung Cancer

Dr. Edward Garon discusses what researchers are learning about MK-3475, an immune therapy treatment currently in clinical trial. February 2014. 


How Do the Different Immune Checkpoint Inhibitors in Lung Cancer Compare?

Dr. Edward Garon warns that it is still too early to compare which immune therapies will be more effective in treating lung cancer.February 2014.


Core Principles of Managing Locally Advanced (Stage III) NSCLC

Here’s a text-heavy but still brief summary “slidedoc” of what I would consider to be the core principles of managing locally advanced, or stage III, non-small cell lung cancer (NSCLC). This is a heterogeneous population that accounts for about 40% of the patients newly diagnosed with NSCLC, with some having far more extensive and bulky disease than others.  Though individual treatment recommendations should be made by the physicians directly reviewing the details of a patient’s case, the key principles still govern the overall plan.

 

 

The hyperlinks are to this earlier Slidedoc: http://www.slideshare.net/JackWestMD/treating-invisible-disease-grace

And here’s the printable pdf file of the slides: Core Principles of Managing Locally Advanced NSCLC

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Do you see PARP inhibitors as a single drug therapy or more in a combination setting?

Dr. Cathy Pietanza of Memorial Sloan Kettering discusses whether PARP treatments can be taken alone or if they must be taken with other drugs. February 2014.


What is the value of maintenance therapy in advanced NSCLC, and who should get it?

We’ve covered the question of maintenance therapy for lung cancer in many posts over the past 5-6 years as it has evolved from a concept with little evidence to a standard of care, but it is difficult to get a good summary of the big picture. This presentation is my attempt to distill the field into the most important principles.

 

What is the value of maintenance therapy in advanced NSCLC, and who should get it? from H. Jack West

And for those who want to download the slides in an easily printable form, here’s the slide set as a pdf file: Maintenance therapy primer

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ALK Positive Lung Cancer Forum 2014: Repeat Biopsies

Why would an ALK lung cancer patient need a repeat biopsy? The doctors discuss the need for and frequency of repeat biopsies.

(IE/Firefox Users: If you have playback problems, please view on YouTube or try the “Download” button above. Get the latest QuickTime Player.)


ALK Positive Lung Cancer Forum 2014: Next Generation ALK Inhibitors

Several new treatments for ALK positive lung cancer patients are on the horizon. In this video, the doctors discuss them while patients in the audience share some of their experiences with side effects on various treatments.

(IE/Firefox Users: If you have playback problems, please view on YouTube or try the “Download” button above. Get the latest QuickTime Player.)


ALK Positive Lung Cancer Forum 2014: Disease Progression While on Xalkori

New treatments for ALK rearrangements are on the horizon. In this video, the doctors discuss how they determine whether or not they change treatments for their patients once they begin to show progression while on Xalkori (crizotinib).

(IE/Firefox Users: If you have playback problems, please view on YouTube or try the “Download” button above. Get the latest QuickTime Player.)


ALK Positive Lung Cancer Forum 2014: Scanning for Progression

How often should ALK patients receive scans to determine if their disease has progressed in various parts of the body?

(IE/Firefox Users: If you have playback problems, please view on YouTube or try the “Download” button above. Get the latest QuickTime Player.)


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