Well, results not great but not horrible. Primary tumor no size change except SUV rose from 3.5 on last PET in March 2013 to 3.9.
Big change is 3 measurable nodules over 1cm spread between both lungs that have not been hypermetabolic since I began Gemzar in Oct. 2011. 2 of them have grown a few mm. and have become hypermetablic, one 1.7 SUV, & the other 2.2, not very high. The 3rd nodule remains the same and not hypermetabolic. But change, progression, nevertheless.
In addition, a new growth of 7mm was found in my middle right lung, a new one, but it is not hypermetabolic - yet. No spread anywhere else and all my lymph nodes are normal. When diagnosed, the first PET/CT had every single lymph node in my chest measurable and hypermetabolic, along with hundreds of small tumors in both lungs, many of which were hypermetabolic. The extent of my disease in my chest was why they gave me only 8 months to live. So with clear and normal lymph nodes, Gemzar is still doing something.
I asked my onc if we can just call it Stable, but he said no, this is Progression, but not "clear" progression, what he would need to call a definite halt to Gemzar. So we are doing another cycle, 3 months then another friggin scan.
He wants us to use the time to prepare me for entrance to a PD-L1 trial that Kaiser is hosting - Hoffman/La Roche MPDL3280A. My onc thinks with my low tumor load and excellent health that I would be a prime candidate if I express enough of PD-L1 ligand for a probability of response. That probably will require another biopsy. So we shall see, He sent me home with all the trial materials to read along with consent forms. I am definitely at a turning point and just am happy that at the end of this next cycle, results good or bad, I will then have had 31 months without having suffered from all the noxious side-effects of chemo treatment and still feeling as though I don't even have Stage IV NSCLC
Also, FISH for ROS1 came back Negative. I appreciate my onc's try.