My wife and I just got back from our visit to a Lung Cancer at U of Penn in Philadelphia. They have the Merck Anti PD1 trial going on there and he agreed with us that the trial is the best bet for my wife who is Stage IV with Spindle Cell (sarcomatoid) carcinoma and whose scans showed progression after 6 months of induction chemo with carbo/taxol/avastin. The problem is that they need to do a biopsy in the next week or so to see if she tests PDL1 positive. If not, she can NOT enter the trial, although the trial did previously include PDL1 negative patients.
So I'm doing contingency planning and am wondering if anyone knows of a Anti PD1 trial that is OPEN to PDL1 negative volunteers. I'd consider the Merck, BMS or Roche drug if necessary. I'm on the east coast outside of Philadelphia. Thanks.