teddy
Posts:9

Is there any research that relates a mother smoking while pregnant to the development of NSCLC with ROS1 rearrangement at 47 yo?

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Reply # - April 10, 2016, 06:04 AM

JimC
Posts: 2753

Hi teddy,

I don't know of any such research, and it's unlikely that it's been done or will be done, since the ROS1 rearrangement is mainly found in non-smokers. In addition, although smoking during pregnancy can pass toxins to the fetus, that would not be the same as the damage to the lungs caused by smoking itself (leading to the mutations that cause lung cancer). Certainly a child exposed to tobacco smoke has a greater risk of developing lung cancer, but probably not with the ROS1 rearrangement.

JimC
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Reply # - April 11, 2016, 04:17 PM

teddy
Posts: 9

Are there any studies in the scientific literature relating the development of NSCLC adenocarcinoma with ROS1 rearrangement of never smokers around age 50 to predisposition caused either through heredity or exposures during fetal development?

Reply # - April 11, 2016, 07:13 PM

catdander
Posts:

Teddy,

I'm not sure how your 2nd question is different than your first.

Janine

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