My husband (NSLC lV diagnosed in May 2005, radiation and chemo, mets to the brain in Dec. 2005 treated with WBR and stereoactic radiation in Feb. 2006) has been on generic Keppra for about 5 years (before he was on Dilantin). The antiseizure drugs were prescribed because he had a seizure before the WBR and because he has every so often (every one or 2 months) a lack of feeling in the left hand and left side of mouth/eye that goes away after a few minutes. He has started to lean to the right side (he has a mild scoliosis) but today it became very pronounced, to the point that he couldnt quite walk. Before he left for his usual walk, he was leaning a little bit and he could balance for a 10 seconds on each leg. When he came back he could barely walk because of the leaning. After seating for a while, he could walk, buthis leaning was quite pronounced (his spine seemed to bend towards the left). I will make an appointment with the neurologist tomorrow (today being memorial day), but for now I need to know if this could be a result of Keppra (the generics tend to change from time to time) and/or if any of you with WBR or steroactic radiation had had a similar experience. While my husband was in Dilantin, he had a similar experience, that time leaning backwards and it was discovered that he had a high Dilantin level in his system… However, they tell me Keppra doesn\'t accumulate in the same way. He seems normal otherwise, just very tired because of the effort to walk after he started leaning so much.
Thank you so much.