jarthur
Posts:3

I recently saw the results of a German study of 1100 patients that indicated that the sensitivity of liquid bx for T790M testing for NSCLC patients was approximately 50%, compared with the gold standard of tissue bx. If this is accurate, would it make sense to do a liquid bx for the mutation and then proceed to tissue bx if the liquid bx result is negative? This strategy might avoid an unnecessary tissue biopsy I ask this question in anticipation of the need for Tagrisso ( or the analogous Clovis agent), my wife having developed resistance to Tarvceva after an excellent result for 15 months.
Thanks in advance

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Reply # - December 30, 2015, 03:37 PM

catdander
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Hi Jarthur,

I would absolutely strongly ask for blood testing first. I'm not a doctor however, my husband had 3 core needle biopsies, one ending in a traumatic lung collapse all without even getting cancer cells (surgery got them). So I may be more passionate about it than some. ;)

Here is a new video discussion on the subject, It's at the beginning of the video. http://cancergrace.org/lung/2015/12/20/ar_2015_qa_riely_horn_acquired_r…

Have you seen these? http://cancergrace.org/lung/acquired-resistance-patient-forum-2014-vide…

I hope she does well for a long long time,
Janine

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