PDL-1 $50,000 Question - 1270116

stash
Posts:4

If the keytruda study clearly indicates the necessity of Pdl-1 receptors for adequate Pdl-1 response (7 VS 45%), is the genetic testing commercially available "before" enrolling in a clinical trial ? I seriously doubt that the manufacturers conducting the studies would reveal during the trial whether patients were responders or not.Thank you for your response. Stash

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JimC
Posts: 2753

Hi Stash,

Testing for PD-L1 is not really standardized, as each manufacturer has their own methods, so at this point patients are stuck with the test as it is performed for a particular trial. Dr. West has discussed this issue in this post, and there is a good discussion in this thread as well.

JimC
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