My daughter has Stage 4 adenocarcinoma NSCLC (ROS1+) dx in December 2015. Standard chemo, then Xalkori gave positive results. The Dr wanted to try Opdivo even though she tested negative for PDL1.This resulted in all masses tripling or more. Then the Dr returned to chemo: Carboplatin and Alimta, then Alimta for maintenance now for 5 months. The Dr has recommended a new combination for an unusual growth? around a previously radiated spot in the lung. I am not sure why this combination when the growth (?) is not identified. Is there any evidence that this should be the next course of treatment given the history of results and unknown cause of this smear in the CT scan?
Wed, 07/12/2017 - 09:26#1
PDL1 negative and ROS1+ on Alimta and Keytruda? - 1291053