My mother-in-law first presented with a small growth on the inner eye-lid. This was removed, and the biopsy showed "Merkel Cell Cancer". At the same time, she was being treated by a Pulmonary specialist for a persistent cough, and he immediately did a chest X-Ray, found something, and the biopsy showed SCLC.
This was all in Summer 2011.
She was treated at Heidelberg Thoraxklinik (The best in Germany?) and had 4x Chemo and a set of brain radiotherapy, which she completed in February 2012. At a check-up in Heidelberg in April, the SCLC was unchanged, (good news) and she was ordered back for late July for another check. She presented two weeks ago with lumps on the neck and in the groin - these have been removed, and confirmed as metastasis in the lymph nodes.
Couple of strange things - Heidelberg re-did the first biopsy of the eye lid growth, because they didn't believe the co-incidence of Merkel Cell and SCLC at the same time. They were right, the growth was a meta from the SCLC, not Merkel Cell.
Second, the new biopsy of the meta in the lymph nodes is showing reaction to SCLC markers, but the tissue is apparently like NSCLC. The pulmonary specialist, who is co-ordinating treatment, describes the case as "Exquisite" and says she should go back to Heidelberg, probably for more Chemo. He talks about a "mixed" NSCLC / SCLC. As I have found no reference to this anywhere, could you tell me if this is possible. If so, what are the treatment options? The SCLC is not operable.
Also, I assume that if the original eye-lid growth was a meta of SCLC; then she was in Extended Disease before the SCLC diagnosis. Is this correct?