First off, I just wanted to share that this forum has been a tremendous source of inspiration, information and comfort since my dad's lung cancer diagnosis in mid-March. Thank you.
My 83 y/o dad ,who smoked between 9 and 15 pack years (his memory has always been poor:), and quit 50 years ago was originally diagnosed with poorly differentiated squamous cell carcinoma of the lung, with features of adenocarcinoma (the oncologist wasn't confident that his cancer could be considered adenosquamous). The initial IHC report was equivocal; it showed markers for both squamous and adeno carcinoma. However, yesterday, my mom and dad met with Dr. Matthew Gubens at UCSF who has been providing a second opinion (on both treatment and diagnosis) and it appears, according to my mom, that the diagnosis, based on UCSF pathology review, has been changed from squamous to adeno. I am trying to get a hold of the pathology report to confirm this change.
My dad has had two rounds of carboplatin/taxol and it appears that he is having a clinical response (his cough is almost gone, and his experience of cancer-related pain seems to be decreasing). In light of the likely new diagnosis and my dad's (apparent response to chemo), I was wondering the following:
1) If the diagnosis is in fact adenocarcinoma, have we screwed up by not using the other chemo combinations recommended for first-line treatment of adenocarcinoma?
2) Can the adeno specific chemos (I think I'm referring to Alimta / Cisplatin) used as second-line treatments with the same response?