Thanking you in advance for this site!
My husband 's mutation is presently: EGFR L858R (exon 21). He has been stable both brain and chest down. He did have SBRT to primary lung mass and SBRT to a liver met.
Present Treatment: Tagrisso @ 40 mg for brain mets and Alimta Maintenance (Cycle 7). He is also managing side-effects fairly well, just has the fatigue, but still manages to go to the gym 2 x per week except for right after chemo..
TREATMENTS THUS FAR:
Nov. 2013..... 1 x carboplatin/alimta, then started Tarceva
Dec. 2013-June 2015.....Tarceva
June 2015.... Biopsy showed T790M, started Clovis Trial; could not tolerate side-effects
Dec. 2015..... Started Tagrisso
May. 2016..... Started progressing on Tagrisso
Sept. 2016.... Biopsy showed T790M dropped
Sept. 2016.... Started carboplatin/alimta + Tagrisso
Question #1: When current treatment fails are there other treatments available besides immunotherapy?
Question #2: Is it possible to go back on Tarceva?
Question #3: What line of treatment thus far as he had (is it considered 3)?
Thanks again for any input you can provide!