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Should EGFR TKI Therapy be Continued Beyond Progression?

Article

Dr. Greg Riely, medical oncologist from MSKCC, discusses the controversial question of whether patients should continue on an oral EGFR tyrosine kinase inhibitor after progression.

  • Read more about Should EGFR TKI Therapy be Continued Beyond Progression?

Patterns of Acquired Resistance to EGFR TKIs in EGFR Mutation-Positive NSCLC

Article

Medical oncologist Dr. Greg Riely, MSKCC, summarizes the development of acquired resistance after a good initial response to EGFR inhibitor therapy and the clinical patterns of progression commonly seen.

  • Read more about Patterns of Acquired Resistance to EGFR TKIs in EGFR Mutation-Positive NSCLC

Are There Distinctions Among Currently Available Oral EGFR Inhibitors for EGFR Mutation-Positive NSCLC?

Article

Dr. Greg Riely, medical oncologist from MSKCC, considers the evidence on whether there are clinically significant differences among the currently available first and second generation oral EGFR inhibitors for patients with an EGFR mutation.

  • Read more about Are There Distinctions Among Currently Available Oral EGFR Inhibitors for EGFR Mutation-Positive NSCLC?

Differences Among Specific EGFR Mutations

Article

Medical oncologist Dr. Greg Riely, MSKCC, discusses evidence for whether there are clinically significant differences among specific EGFR mutations that should lead to differences in management.

  • Read more about Differences Among Specific EGFR Mutations

Should Avastin be Added to EGFR TKI Therapy for EGFR Mutation-Positive NSCLC?

Article

Dr. Jack West, medical oncologist, reviews evidence in favor of adding Avastin (bevacizumab) to the EGFR inhibitor Tarceva (erlotinib) for patients with lung cancer that harbors an activating EGFR mutation.

  • Read more about Should Avastin be Added to EGFR TKI Therapy for EGFR Mutation-Positive NSCLC?

What is Maintenance Therapy for Advanced NSCLC?

Article

The concept of maintenance therapy for advanced lung cancer has emerged over the past few years. Dr. Jack West, medical oncologist, reviews the concepts behind it and treatment options for patients.

  • Read more about What is Maintenance Therapy for Advanced NSCLC?

Join GRACE at the 2015 ALK, ROS1 & EGFR Lung Cancer Patient Forum

Article

WHAT: Acquired Resistance in Lung Cancer Patient Forum
WHEN: Saturday, Oct. 3, 2015
WHERE: Marriott Waterfront San Francisco, 1800 Old Bayshore Hwy, Burlingame, CA 94010
WHO: ALK, ROS1 & EGFR lung cancer patients and their caregivers

REGISTER HERE

  • Read more about Join GRACE at the 2015 ALK, ROS1 & EGFR Lung Cancer Patient Forum
  • 8 comments

RET in Lung Cancer: The Next Big Target?

Article

A trial studying Cometriq (cabozantinib) for RET rearrangements showed a promising response rate, which led the doctors to discuss if they think RET is going to be the next actionable target in lung cancer.

 

Please feel free to offer comments and raise questions in our Discussion Forums.

 

  • Read more about RET in Lung Cancer: The Next Big Target?
  • 1 comment

Adding to Tarceva in a Broad NSCLC Population: Weighing Benefits with Risks

Article

ASCO 2015 Highlights 07

 

A trial comparing Tarceva (erlotinib) to Cometriq (cabozantinib) showed modest benefit for EGFR wild type patients, but the challenging side effect profile should lead us to question if we can identify only patients most likely to benefit from Cometriq.

[powerpress]

  • Read more about Adding to Tarceva in a Broad NSCLC Population: Weighing Benefits with Risks

Debating EGFR Inhibitors for Squamous Cell Lung Cancer Patients

Article

ASCO 2015 Highlights 06

 

Squamous cell carcinoma patients have limited options. Data presented at ASCO 2015 showed positive patient outcomes with Gilotrif (afatinib) vs Tarceva (erlotinib), but some feel that there is little value in a treatment with only modestly better results.

[powerpress]

  • Read more about Debating EGFR Inhibitors for Squamous Cell Lung Cancer Patients

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  • FIGHT
    • Coping with Cancer
      • Just Diagnosed
      • In Treatment
      • In Remission
      • Survivorship
    • Cancer Information
      • Bladder Cancer
      • Blood Cancer
      • Breast Cancer
      • Head and Neck Cancer
      • Lung Cancer
      • Melanoma
      • Other
      • Latest Featured Content
      • The Archives
      • Other Resources
    • Find Clinical Trials
    • Glossary
      • Cancer FAQs
  • EDUCATE
    • Current Patient Education Video Series
      • Coronavirus and Covid 19 in the Cancer Community
      • Cancer Information for the Latino Community
      • 2020-21 Patient Education Ambassador's Program
    • GRACE Podcasts
    • Video Library
      • English
      • Spanish
      • Mandarin
  • PARTICIPATE
    • Community Forum
      • Bladder Cancer
      • Blood Cancer
      • Brain Cancer
      • Breast Cancer
      • Colorectal Cancer
      • Gall Bladder and Bile Duct Cancer (Cholangiocarcinoma)
      • Head and Neck Cancer
      • Kidney Cancer
      • Lung Cancer
      • Melanoma
      • Member Updates
      • General Forums
      • Ask A Question
    • Get Involved
      • Memorials and Tributes
      • Volunteer Opportunities
  • ABOUT CancerGRACE
    • GRACE NEWS AND INFO
      • Contact Us
      • How (and Why) to Use GRACE
      • GRACE Public Disclosure Documentation
    • About GRACE
      • Mission
      • Opportunities
      • Terms of Use
      • Our Supporters 2020
    • Our Team
      • Faculty
      • Staff and Board
    • Partnerships
      • GRACE and Clinical Care Options Patient Tools
      • Varian Partner Page 2020
      • Takeda Oncology Partnership Page 2020
      • Lilly Oncology Partner Page
  • DONATE
    • Why Give to GRACE
      • More Ways to Give
      • Corporate Giving Programs
      • Gifts of Stock or Securities
      • Shop and Search for the Cause
      • Create a Tribute
      • Create Your Own Fundraiser
      • Shop with GRACE