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Going back to Tarceva from Tagrisso?

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General NSCLC

March 18, 2018 at 1:24 am #1294108

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Tarceva and ammonia levels

Forums
General NSCLC

Has there been any correlation between taking Tarceva and increased in blood ammonia levels? I have a sister, age 61 who has vulvar cancer stage IV and she recently started taking Tarceva as of January 21st. She was sent to the ER for possible stroke but that has been ruled out. Only abnormal was her ammonia level.

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Translation of Molecular Genetics in Lung Cancer into Treatment Decision

Article
  1. Christine M. Walko, Pharm.D., discusses how advancements in technology have improved the quality, cost and turnaround time for assessing genetic mutations in tumor tissue, and how this has helped to translate precision medicine into standard clinical practice.
  • Read more about Translation of Molecular Genetics in Lung Cancer into Treatment Decision

Maintenance Therapy for Advanced NSCLC

Video

Dr. Jack West, Swedish Cancer Institute, defines maintenance therapy in advanced NSCLC and discusses maintenance treatment strategies.

  • Read more about Maintenance Therapy for Advanced NSCLC

Combinations and Other Options for Acquired Resistance in EGFR Mutation-Positive NSCLC

Video

Dr. Nathan Pennell, Cleveland Clinic, describes other options for treatment of acquired resistance, including chemotherapy, ablation with SBRT and a combination of Gilotrif and Erbitux.

  • Read more about Combinations and Other Options for Acquired Resistance in EGFR Mutation-Positive NSCLC

Third Generation EGFR TKIs for Acquired Resistance

Video

Dr. Nathan Pennell, Cleveland Clinic, discusses the concept of acquired resistance and new agents designed to address it, including Rociletinib and Merelitinib.

  • Read more about Third Generation EGFR TKIs for Acquired Resistance

Targeted Therapies in a Post-Operative/Adjuvant Setting

Video

Dr. Nathan Pennell, Cleveland Clinic, reviews the available trial evidence for the use of targeted therapies in the post-operative/adjuvant setting.

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Emerging Options for T790M-Positive Acquired Resistance

Video

Acquired resistance in EGFR patients is often driven by the T790M mutation. T790M-positive tumors respond differently to treatments than T790M-negative tumors. Dr. Greg Riely details how each status can predict patients' responses to current treatments.

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Does the Specific EGFR Mutation (Including "Rare" Mutations) Matter When Choosing an Oral EGFR Inhibitor?

Article

Drs. Leora Horn, Ben Solomon, & Jack West discuss the open question of whether there are clinically significant differences among leading EGFR tyrosine kinases based on the specific EGFR mutation to be treated.

  • Read more about Does the Specific EGFR Mutation (Including "Rare" Mutations) Matter When Choosing an Oral EGFR Inhibitor?

First Line Treatment of EGFR Mutation-Positive NSCLC

Article

MSKCC medical oncologist Dr. Greg Riely reviews the optimal first line treatment of patients with an EGFR mutation-positive advanced lung cancer.

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      • Head and Neck Cancer News and Updates ASCO / ESMO
      • Lung Cancer Video Library - English
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  • PARTICIPATE
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      • Bladder Cancer
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      • Our Supporters 2020
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      • GRACE and Clinical Care Options Patient Tools
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      • Takeda Oncology Partnership Page 2020
      • Lilly Oncology Partner Page
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