Has anyone had mixed results from chemo/immunotherapy? My uncle was diagnosed with stage iv nsclc (exon 20 mutation). It has spread to the bones, lymph nodes and adrenal glands. He did 6 rounds of chemo with immunotherapy (alimta/keytruda/carbo) and then continued with keytruda/alimta. We just received his first PET and brain MRI results since his initial diagnosis and while some of the cancer shrunk, some grew and there are new lesions not seen in April. The oncologist said not to be alarmed and wants to continue immunotherapy and re-test in three months. Is that a typical response/course of treatment for mixed results from chemo? I'm very concerned about the new growth.