Diagnosed September 2011, NSCLC , Adenocarcinoma stage 3B (Pancoast tumor with Horners syndrome). Initial treatment was six weeks of radiation to the lung with chemo – Cisplatin and Etopiside – four cycles. The results were great, did another two cycles of the chemo to mop up any stray cells. Was NED for a short time – from April 2012 to July 2012. A met was found on my rib, causing a fracture (now stage IV). I sought out second and third opinions. We did more chemo – tried two cycles Carboplatin and Alimta. It was not effective, this was roughly September 2012. Then we tried Carboplatin/Taxol/Avastin starting in late November 2012. Cyberknife was done to the rib met in February. I just has a CT with contrast. The results were pretty good, stable (no shrinkage), post radiation changes, etc. One note did say “small areas of nodularity are seen on image 18 series 4 not currently seen on the previous study”. My oncologist wants to start me on another 4 cycles of Carbo/Taxol/Avastin. It seems strange to me to continue with the same chemo, especially the carboplatin. I am faced with making a decision to continue this or not. In my mind there is no proof the chemo is working but there is also no proof it’s not. I have handled the chemo exceptionally well with minimal side effects; hair loss and minimal fatigue. My platelets were an issue, they would drop low and had to postpone chemo for two weeks and then back to normal. I am worried about long term effects of the chemo. I did have mutation testing done and am negative for all mutations.
My question is this: Does this seem like a good plan or is it time to see my second opinion doctor?
Thank you in advance,