My wife is taking treatment for EGFR mutant lung cancer that had spread to her brain. She started with tagrisso and later after resistant went thru chemo drugs and they are not helping. We are planning to try erlotinib (tarceva). The recent molecular shows the mutant as EGFR e746_s752 (exon 19 deletion ) and same as it was before 2 years ago except it had formed resistant to egfr c797s so tagrisso did not work.
We would like to know if anybody gone thru treatment with tarceva and how effective it was to the Brain. Please share you experience about that drug and if you had taken it for cancer that spread to brain. Another option is to try trial drug poziotinib. Thanks in advance.