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What's the difference between wild type and non-wild type of the K-RAS mutation? I can't seem to find any info on the non-wild type. Would they be treated the same? Does the non-wild type have a worse prognosis?
Take care, Judy
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Reply # - July 15, 2013, 07:05 PM
Reply To: K-RAS mutation
wild type just means a person doesn't have the mutation.
So a person who's K RAS wild type doesn't have the mutation. I've not heard the term non wild type.
Reply # - July 15, 2013, 07:54 PM
Reply To: K-RAS mutation
Right. Wild type = no mutation. KRAS mutation positive tends to be associated with a worse prognosis in NSCLC, though not every study shows that. Some show no significant difference in prognosis between KRAS mutation positive and KRAS wild type.
-Dr. West
Reply # - July 16, 2013, 11:05 AM
Reply To: K-RAS mutation
So there is no non-wild type? Or is that what you're calling KRAS mutation positive?
Take care, Judy
Reply # - July 16, 2013, 04:05 PM
Reply To: K-RAS mutation
KRAS mutation positive = not wild type.
Reply # - July 16, 2013, 06:05 PM
Reply To: K-RAS mutation
Thanks Dr. West for clarifying. Take care, Judy