Thu, 03/13/2014 - 04:00
The evidence on "rechallenge" suggests that a small minority of patients will demonstrate a significant response (tumor shrinkage) -- under 10% -- but a much more sizable proportion will demonstrate stable disease or perhaps a small amount of tumor shinkage. This doesn't tend to be a long lasting response the second time around (most typically 3-5 months), but it's potentially valuable.
Thu, 03/13/2014 - 06:55
I restarted 5 weeks ago and have my first scan in 3 weeks time. We are hoping it will either kick in again, or put me on track to join the CO 1686 trial.
Please let us know how you go.
Fri, 03/14/2014 - 22:50
Good luck on your upcoming scan and the whole treatment plan, Gail!
Thanks Dr. West on your response and March 10 post on new drugs to be watched that may successfully deal with Tarceva resistance . I'm sure we'll all be watching and waiting for the latest and hope for great news.
Please keep on keeping on for us fighters all over the world.
God bless us all always and forever.
Sat, 03/15/2014 - 08:58
Yes, these are exciting times, and I'm very gratified to finally see light breaking through cracks in the walls of acquired resistance for patients with an EGFR mutation. I will relay new information as it becomes available.