jane1980
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Posts:5
My father has two muscle mets from squamous NSCLC.
He has had three cycles of carbo+vinorelbine. PET scan shows that the biggest met has enlarged a bit and SUV has changed from 10 to 6. No change in the small met (SUV 4).
Is this considered a response to chemo?
Thank you very much in advance.
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Reply # - March 26, 2015, 04:36 AM
Hi Jane,
Hi Jane,
In the technical sense of the word "response" as used in clinical trials (a reduction of fifty percent in tumor size), this would not be considered a response. But in terms of whether treatment has been effective, it would depend on how much growth "a bit" represents. One met appears to be stable and the other has a reduced SUV. If the increase is size is minimal, that could simply represent the difference between two scans and not real growth. For advanced lung cancer, a finding that tumors/mets are stable means that treatment has been effective.
As Dr. Creelan stated in one of your earlier threads, if your father continues to experience pain from these mets then radiation may be an option.
JImC
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Reply # - March 26, 2015, 04:47 AM
Thank you very much Jim for
Thank you very much Jim for your quick answer.
Our oncologist has suggested a fourth cycle of chemo. Then stop chemo and start radiation to both mets using a curative dose in order to inactivate both mets, if possible.