Scared and confused - 1271693

My husband of 27 years was diagnosed May 28th, 2015 with Stage 4 Non small cell lung cancer, adenocarcinoma with numerous metastases to both bone and muscle. In the last 3.5 months we have found out the following: left lung upper lobe 1.7cm (biopsied), L2 and L5 vertebrae (biopsied), left and right adrenal glands (left biopsied), left branchi tube, left and right low anterior neck lymph nodes, numerous retro-peritoneal fat mets, numerous left hylar lymph nodes mets, right posterior paraspinal muscle (biopsied), left infraspinatus muscle (biopsied), right gluteus minimus muscle (biopsied), left supraclavicular lymph nodes, left para-tracheal node, Spleen, right 6th rib, anterior right chest wall, and bilateral renal met. Fortunately no Brain mets. I believe that covers everything. They have done Radiation to the gluteus minimus muscle due to pain and also to the L2 tumor on his spine. He has also had 3 chemo treatments of Pemetrexed and Carboplatin and will have his 4th on Monday. He was on a trial program for MD-3475 but was not chosen to receive the drug, he was then removed from the Trial because of the radiation for his hip. He was in severe pain with his back and radiation on L2 helped with that, the tumor shrunk partially on one side but grew on the other side. The radiation on his hip has relieved his pain there also. He has had severe nausea and vomiting for about 2 months now and has lost almost 40lbs since the end of May. So far the chemo has stabilized or shrunk thing minimally. Because of the extensive places he has cancer he has 4 oncologists at MD Anderson in Houston monitoring all of this. He also has none of the known mutations except TP53. PD1 is negative. How do we have hope when even the doctors don't?