The ADAURA clinic trial has proven that patients taking Tagrisso with IB-IIIA NSCLC had a 79% reduction in disease recurrence and the disease free survival rates were 89%. Based on this trial I of course want to get on this medication ASAP. Unfortunately, it hasn't been FDA approved for my group (Stage IIIA) yet and therefore my insurnce will not pay for it. Does anyone have any idea how I can obtain this medicine at a somewhat affordabel cost? Will Beacon Pharma sell Tagrix to me since I live in the US? Does Bonhoa have legitimate medication? All help is appreciated!
Reply # - August 20, 2020, 08:56 PM
Hi UTFight, I'm sorry you're in this worrisome (to say the least) situation. I'm sorry too that I missed it when you posted.
Dr. West and Dr. Sequist discuss the ADAURA trial presented at ASCO this June the exciting possible added benefit and the possible pitfalls of assuming DFS (disease free survival) equates to OS (overall survival). The data as they stand suggest as you'd expect tagrisso at the very least keeps recurrence at bay. But does it cure the cancer or is it just keeping the cancer at bay? If it's just keeping the cancer at bay the OS may not be as good as if you recur. There are just no answers at the moment.
All that to say read the discussion, it's always invaluable to read what West and Sequist have to say. I don't know when you had surgery but one thing they remind us, and I paraphrase, adjuvant therapy works to clean up what surgery didn't get. But if you wait too long that systemic treatment no longer acts in the adjuvant capacity. That usually around 6 to 12 weeks out from surgery that you'd want to start. Otherwise, you're just taking a lot of expensive, toxic drugs.
I don't know the pricing of tagrix or to whom they sell and I don't know anything about Bonhoa.
I hope you are cured with or without osimertinib.
All the best,
I joined GRACE as a caregiver for my husband who had a Pancoast tumor, NSCLC stage III in 2009. He had curative chemo/rads then it was believed he had a recurrence in the spine/oligometastasis that was radiated. He's 10 years out from treatment.