Tarceva and Green Tea Extract - 1268940

Dr. Walko a faculty member on Grace and Oncology Pharmacologist had this to say about the interaction, "I will say that green tea is known to block the common enzyme (CYP3A4) that breaks down gefitinib and so use of green tea can increase the amount of gefinitib in the body and lead to more side effects. A logical question is “how much” green tea and this is something that is not well known since different green tea extracts contain differing amounts of the substances that can block enzymes." http://cancergrace.org/topic/pleas-advise-me-thank-you-very-much/#post-…

I hope this helps,
Janine