My husband has been on Tarceva 150 mg for 4 months. In January he had his first scan since starting it. He had 30% shrinkage of the 4 cm primary tumor (50% previously with traditional chemotherapy). At that visit the oncologist said it looked like a "donut hole" and she showed it to us which it did look like that. Had a scan just this Monday and she said unequivocally that it showed scar tissue. The nurse practitioner called the next day and said that it has "slightly increased but is stable" which is not what the oncologist said.
My question is what does Tarceva actually do to the tumor?