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  3. What to expect - brain mets with stage iv nsclc in 81--year-old mom - 1271692

Translation of Molecular Genetics in Lung Cancer into Treatment Decision

Article
  1. Christine M. Walko, Pharm.D., discusses how advancements in technology have improved the quality, cost and turnaround time for assessing genetic mutations in tumor tissue, and how this has helped to translate precision medicine into standard clinical practice.
  • Read more about Translation of Molecular Genetics in Lung Cancer into Treatment Decision

HER2 Mutation Positive NSCLC

Video

Dr. Nathan Pennell, Cleveland Clinic, describes treatment of NSCLC patients with HER2 mutations using agents such as Gilotrif or Herceptin.

  • Read more about HER2 Mutation Positive NSCLC

Combinations and Other Options for Acquired Resistance in EGFR Mutation-Positive NSCLC

Video

Dr. Nathan Pennell, Cleveland Clinic, describes other options for treatment of acquired resistance, including chemotherapy, ablation with SBRT and a combination of Gilotrif and Erbitux.

  • Read more about Combinations and Other Options for Acquired Resistance in EGFR Mutation-Positive NSCLC

Direct Comparison of 2 EGFR Inhibitors Shows There Are Clinically Significant Differences

Article

Fast forward 1.5 years, and we now have the early results of LUX-Lung-7, and they show that these EGFR TKIs are not completely interchangeable...

  • Read more about Direct Comparison of 2 EGFR Inhibitors Shows There Are Clinically Significant Differences
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Panel Q&A Session on Sequencing EGFR Treatments with Drs. Riely and West

Video

Drs. Jack West and Greg Riely field questions about which treatments should EGFR lung cancer patients consider when their cancers progress.

  • Read more about Panel Q&A Session on Sequencing EGFR Treatments with Drs. Riely and West

Treatment Options for EGFR T790M Negative Acquired Resistance

Video

Dr. Jack West suggests that progression in T790M-negative EGFR lung cancer patients may not require a change in therapy. In this video he details what should go into the decision to modify treatment for those patients.

  • Read more about Treatment Options for EGFR T790M Negative Acquired Resistance

Emerging Options for T790M-Positive Acquired Resistance

Video

Acquired resistance in EGFR patients is often driven by the T790M mutation. T790M-positive tumors respond differently to treatments than T790M-negative tumors. Dr. Greg Riely details how each status can predict patients' responses to current treatments.

  • Read more about Emerging Options for T790M-Positive Acquired Resistance

Does the Specific EGFR Mutation (Including "Rare" Mutations) Matter When Choosing an Oral EGFR Inhibitor?

Article

Drs. Leora Horn, Ben Solomon, & Jack West discuss the open question of whether there are clinically significant differences among leading EGFR tyrosine kinases based on the specific EGFR mutation to be treated.

  • Read more about Does the Specific EGFR Mutation (Including "Rare" Mutations) Matter When Choosing an Oral EGFR Inhibitor?

First Line Treatment of EGFR Mutation-Positive NSCLC

Article

MSKCC medical oncologist Dr. Greg Riely reviews the optimal first line treatment of patients with an EGFR mutation-positive advanced lung cancer.

  • Read more about First Line Treatment of EGFR Mutation-Positive NSCLC

Should EGFR TKI Therapy be Continued Beyond Progression?

Article

Dr. Greg Riely, medical oncologist from MSKCC, discusses the controversial question of whether patients should continue on an oral EGFR tyrosine kinase inhibitor after progression.

  • Read more about Should EGFR TKI Therapy be Continued Beyond Progression?

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  • EDUCATE
    • Current Patient Education Video Series
      • ASCO Lung Roundtable
      • Bladder Cancer Video Library
      • Blood Cancer Video Library
      • Cancer Information for the Latino Community
      • Case Based Panel Discussions
      • Clinical Trials Experiences Through Storytelling
      • Covid-19 and Cancer
      • East Asian Lung Cancer Video Library
      • HPV Advances - A Patient Education Program
      • Head and Neck Cancer News and Updates ASCO / ESMO
      • Lung Cancer Video Library - English
      • Lung Cancer Video Library - Spanish
      • Lung OncTalk
      • Melanoma Video Library
      • Patient Education Ambassador Program
      • Targeted Therapies Patient Forum - English
      • Targeted Therapies Patient Forum - Spanish
      • Testing and Early Diagnosis
    • GRACE Podcasts
    • Video Library
      • English
      • Spanish
      • Mandarin
  • PARTICIPATE
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      • Bladder Cancer
      • Blood Cancer
      • Brain Cancer
      • Breast Cancer
      • Colorectal Cancer
      • Gall Bladder and Bile Duct Cancer (Cholangiocarcinoma)
      • Head and Neck Cancer
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      • Lung Cancer
      • Melanoma
      • Member Updates
      • General Forums
      • Ask A Question
    • Get Involved
      • Memorials and Tributes
      • Volunteer Opportunities
  • ABOUT CancerGRACE
    • GRACE NEWS AND INFO
      • Contact Us
      • How (and Why) to Use GRACE
      • GRACE Public Disclosure Documentation
    • About GRACE
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      • Our Supporters 2020
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      • Staff and Board
    • Partnerships
      • GRACE and Clinical Care Options Patient Tools
      • Varian Partner Page 2020
      • Takeda Oncology Partnership Page 2020
      • Lilly Oncology Partner Page
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      • More Ways to Give
      • Corporate Giving Programs
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      • Shop and Search for the Cause
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